Articles scientifiques

Copy Number Aberration Analysis to Predict Response to Neoadjuvant Anti-HER2 Therapy: Results from the NeoALTTO Phase III Clinical Trial.

Auteurs : Venet D, Rediti M, Maetens M, Fumagalli D, Brown DN, Majjaj S, Salgado R, Pusztai L, Harbeck N, El-Abed S, Wang Y, Saura C, Gomez H, Semiglazov VF, de Azambuja E, Huober J, Nuciforo P, Di Cosimo S, Piccart-Gebhart M, Loi S, Rothé F, Sotiriou C
Année : 2021
Journal : Clin Cancer Res
Volume : 27
Pages : 5607-5618

Phylogenetic reconstruction of breast cancer reveals two routes of metastatic dissemination associated with distinct clinical outcome.

Auteurs : Venet D, Fimereli D, Rothé F, Boeckx B, Maetens M, Majjaj S, Rouas G, Capra M, Bonizzi G, Contaldo F, Galant C, Piccart-Gebhart M, Pruneri G, Larsimont D, Lambrechts D, Desmedt C, Sotiriou C
Année : 2020
Journal : EBioMedicine
Volume : 56
Pages : 102793

Digital analysis of distant and cancer-associated mammary adipocytes.

Auteurs : Isnaldi E, Richard F, De Schepper M, Vincent D, Leduc S, Maetens M, Geukens T, Floris G, Rouas G, Cardoso F, Sotiriou C, Zoppoli G, Larsimont D, Biganzoli E, Desmedt C
Année : 2020
Journal : Breast
Volume : 54
Pages : 179-186

Tumor sequencing is useful to refine the analysis of germline variants in unexplained high-risk breast cancer families.

Auteurs : Van Marcke C, Helaers R, De Leener A, Merhi A, Schoonjans CA, Ambroise J, Galant C, Delrée P, Rothé F, Bar I, Khoury E, Brouillard P, Canon JL, Vuylsteke P, Machiels JP, Berlière M, Limaye N, Vikkula M, Duhoux FP
Année : 2020
Journal : Breast Cancer Res
Volume : 22
Pages : 36

Reply to S. A. Narod et al.

Auteurs : Azim HA Jr, Ameye L, Paesmans M, Lambertini M
Année : 2020
Journal : J Clin Oncol
Volume : 38
Pages : 4352-4354

Computed tomography-based analyses of baseline body composition parameters and changes in breast cancer patients under treatment with CDK 4/6 inhibitors.

Auteurs : Franzoi MA, Vandeputte C, Eiger D, Caparica R, Brandão M, de Angelis C, Hendlisz A, Awada A, Piccart-Gebhart M, de Azambuja E
Année : 2020
Journal : Breast Cancer Res Treat
Volume : 181
Pages : 199-209

Prognostic and Predictive Impact of Beta-2 Adrenergic Receptor Expression in HER2-Positive Breast Cancer.

Auteurs : Caparica R, Richard F, Brandão M, Awada A, Sotiriou C, de Azambuja E
Année : 2020
Journal : Clin Breast Cancer
Volume : 20
Pages : 262-273.e7

Lessons learned at SABCS 2019 and to-dos from immunotherapy in breast cancer.

Auteurs : Eiger D, Brandão M, de Azambuja E
Année : 2020
Journal : ESMO Open
Volume : 5

PD-1 protein and gene expression as prognostic factors in early breast cancer.

Auteurs : Matikas A, Zerdes I, Lövrot J, Sifakis E, Richard F, Sotiriou C, Rassidakis G, Bergh J, Valachis A, Foukakis T
Année : 2020
Journal : ESMO Open
Volume : 5

The core spliceosomal factor U2AF1 controls cell-fate determination via the modulation of transcriptional networks.

Auteurs : Laaref AM, Manchon L, Bareche Y, Lapasset L, Tazi J
Année : 2020
Journal : RNA Biol
Volume : 17
Pages : 857-871

Healthcare use and costs in early breast cancer: a patient-level data analysis according to stage and breast cancer subtype.

Auteurs : Brandão M, Morais S, Lopes-Conceição L, Fontes F, Araújo N, Dias T, Pereira D, Borges M, Pereira S, Lunet N
Année : 2020
Journal : ESMO Open
Volume : 5

Cardiotoxicity of trastuzumab given for 12 months compared to shorter treatment periods: a systematic review and meta-analysis of six clinical trials.

Auteurs : Eiger D, Franzoi MA, Pondé N, Brandão M, de Angelis C, Schmitt Nogueira M, de Hemptinne Q, de Azambuja E
Année : 2020
Journal : ESMO Open
Volume : 5

The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice.

Auteurs : Gonzalez-Ericsson PI, Stovgaard ES, Sua LF, Reisenbichler E, Kos Z, Carter JM, Michiels S, Le Quesne J, Nielsen TO, Lænkholm AV, Fox SB, Adam J, Bartlett JM, Rimm DL, Quinn C, Peeters D, Dieci MV, Vincent-Salomon A, Cree I, Hida AI, Balko JM, Haynes HR, Frahm I, Acosta-Haab G, Balancin M, Bellolio E, Yang W, Kirtani P, Sugie T, Ehinger A, Castaneda CA, Kok M, McArthur H, Siziopikou K, Badve S, Fineberg S, Gown A, Viale G, Schnitt SJ, Pruneri G, Penault-Llorca F, Hewitt S, Thompson EA, Allison KH, Symmans WF, Bellizzi AM, Brogi E, Moore DA, Larsimont D, Dillon DA, Lazar A, Lien H, Goetz MP, Broeckx G, El Bairi K, Harbeck N, Cimino-Mathews A, Sotiriou C, Adams S, Liu SW, Loibl S, Chen IC, Lakhani SR, Juco JW, Denkert C, Blackley EF, Demaria S, Leon-Ferre R, Gluz O, Zardavas D, Emancipator K, Ely S, Loi S, Salgado R, Sanders M
Année : 2020
Journal : J Pathol
Volume : 250
Pages : 667-684

Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells.

Auteurs : Gómez-Aleza C, Nguyen B, Yoldi G, Ciscar M, Barranco A, Hernández-Jiménez E, Maetens M, Salgado R, Zafeiroglou M, Pellegrini P, Venet D, Garaud S, Trinidad EM, Benítez S, Vuylsteke P, Polastro L, Wildiers H, Simon P, Lindeman G, Larsimont D, Van den Eynden G, Velghe C, Rothé F, Willard-Gallo K, Michiels S, Muñoz P, Walzer T, Planelles L, Penninger J, Azim HA Jr, Loi S, Piccart-Gebhart M, Sotiriou C, González-Suárez E
Année : 2020
Journal : Nat Commun
Volume : 11
Pages : 6335

The 2019 World Health Organization classification of tumours of the breast.

Auteurs : Tan PH, Ellis I, Allison K, Brogi E, Fox SB, Lakhani S, Lazar AJ, Morris EA, Sahin A, Salgado R, Sapino A, Sasano H, Schnitt S, Sotiriou C, van Diest P, White VA, Lokuhetty D, Cree IA
Année : 2020
Journal : Histopathology
Volume : 77
Pages : 181-185

Association between the histopathological growth patterns of liver metastases and survival after hepatic surgery in breast cancer patients.

Auteurs : Bohlok A, Vermeulen P, Leduc S, Latacz E, Botzenhart L, Richard F, De Schepper M, Geukens T, Lucidi V, Ignatiadis M, Aftimos P, Sotiriou C, Piccart-Gebhart M, Hendlisz A, Van Laere S, Dirix L, Noël JC, Biganzoli E, Larsimont D, Desmedt C, Donckier V
Année : 2020
Journal : NPJ Breast Cancer
Volume : 6
Pages : 64

What Is the Real Impact of Estrogen Receptor Status on the Prognosis and Treatment of HER2-Positive Early Breast Cancer?

Auteurs : Brandão M, Caparica R, Malorni L, Prat A, Carey LA, Piccart-Gebhart M
Année : 2020
Journal : Clin Cancer Res
Volume : 26
Pages : 2783-2788

Treatment and Other Healthcare Use of Breast Cancer Patients With a Previous Cancer Diagnosis.

Auteurs : Morais S, Costa AR, Lopes-Conceicao L, Brandão M, Borges M, Araujo N, Dias T, Fontes F, Pereira S, Lunet N
Année : 2020
Journal : Anticancer Res
Volume : 40
Pages : 1041-1048

Pan-cancer analysis of whole genomes.

Auteurs : Campbell PJ, Sotiriou C, Larsimont D, et al.
Année : 2020
Journal : Nature
Volume : 578
Pages : 82-93

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer.

Auteurs : Kos Z, Roblin E, Kim RS, Michiels S, Gallas BD, Chen W, van de Vijver KK, Goel S, Adams S, Demaria S, Viale G, Nielsen TO, Badve SS, Symmans WF, Sotiriou C, Rimm DL, Hewitt S, Denkert C, Loibl S, Luen SJ, Bartlett JMS, Savas P, Pruneri G, Dillon DA, Cheang MCU, Tutt A, Hall JA, Kok M, Horlings HM, Madabhushi A, van der Laak J, Ciompi F, Lænkholm AV, Bellolio E, Gruosso T, Fox SB, Araya JC, Floris G, Hudecek J, Voorwerk L, Beck AH, Kerner J, Larsimont D, Declercq S, Van den Eynden G, Pusztai L, Ehinger A, Yang W, AbdulJabbar K, Yuan Y, Singh R, Hiley C, Bakir MA, Lazar AJ, Naber S, Wienert S, Castillo M, Curigliano G, Dieci MV, André F, Swanton C, Reis-Filho J, Sparano J, Balslev E, Chen IC, Stovgaard EIS, Pogue-Geile K, Blenman KRM, Penault-Llorca F, Schnitt S, Lakhani SR, Vincent-Salomon A, Rojo F, Braybrooke JP, Hanna MG, Soler-Monsó MT, Bethmann D, Castaneda CA, Willard-Gallo K, Sharma A, Lien HC, Fineberg S, Thagaard J, Comerma L, Gonzalez-Ericsson P, Brogi E, Loi S, Saltz J, Klaushen F, Cooper L, Amgad M, Moore DA, Salgado R
Année : 2020
Journal : NPJ Breast Cancer
Volume : 6
Pages : 17