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 Related scientific articles (all)

Genomic aberrations in young and elderly  breast cancer patients.

Authors : Azim HA, Nguyen B, Brohée S, Zoppoli G, Sotiriou C
Year : 2015
Journal : BMC Med
Volume : 13
Pages : 266

Evolving paradigms in multifocal breast cancer.

Authors : Salgado R, Aftimos P, Sotiriou C, Desmedt C
Year : 2015
Journal : Semin. Cancer Biol.
Volume : 31C
Pages : 111-118

Integrative proteomic and gene expression analysis identify potential biomarkers for adjuvant trastuzumab resistance: analysis from the Fin-her phase III randomized trial.

Authors : Sonnenblick A, Brohée S, Fumagalli D, Rothé F, Vincent D, Ignatiadis M, Desmedt C, Salgado R, Sirtaine N, Loi S, Neven P, Loibl S, Denkert C, Joensuu H, Piccart-Gebhart M, Sotiriou C
Year : 2015
Journal : Oncotarget
Volume : 6
Pages : 30306-16

Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome.

Authors : Fumagalli D, Gacquer D, Rothé F, Lefort A, Libert F, Brown D, Kheddoumi N, Shlien A, Konopka T, Salgado R, Larsimont D, Polyak K, Willard-Gallo K, Desmedt C, Piccart-Gebhart M, Abramowicz M, Campbell PJ, Sotiriou C, Detours V
Year : 2015
Journal : Cell Rep
Volume : 13
Pages : 277-89

Immunology and breast cancer: toward a new way of understanding breast cancer and developing novel therapeutic strategies.

Authors : Gingras I, Azim HA Jr, Ignatiadis M, Sotiriou C
Year : 2015
Journal : Clin Adv Hematol Oncol
Volume : 13
Pages : 372-82

St Gallen International Expert Consensus on the primary therapy of early breast cancer: an invaluable tool for physicians and scientists.

Authors : Ignatiadis M, Buyse M, Sotiriou C
Year : 2015
Journal : Ann Oncol
Volume : 26(8)
Pages : 1519-20

Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity.

Authors : Van Keymeulen A, Lee MY, Ousset M, Brohée S, Rorive S, Giraddi RR, Wuidart A, Bouvencourt G, Dubois C, Salmon I, Sotiriou C, Phillips WA, Blanpain C
Year : 2015
Journal : Nature
Volume : 525(7567
Pages : 119-23

Constitutive phosphorylated STAT3-associated gene signature is predictive for trastuzumab resistance in primary HER2-positive breast cancer.

Authors : Sonnenblick A, Brohée S, Fumagalli D, Vincent D, Venet D, Ignatiadis M, Salgado R, Van den Eynden G, Rothé F, Desmedt C, Neven P, Loibl S, Denkert C, Joensuu H, Loi S, Sirtaine N, Kellokumpu-Lehtinen PL, Piccart-Gebhart M, Sotiriou C
Year : 2015
Journal : BMC Med
Volume : 13(1)
Pages : 177

Subclonal diversification of primary breast cancer revealed by multiregion sequencing.

Authors : Yates LR, Gerstung M, Knappskog S, Desmedt C, Gundem G, Van Loo P, Aas T, Alexandrov LB, Larsimont D, Davies H, Li Y, Ju YS, Ramakrishna M, Haugland HK, Lilleng PK, Nik-Zainal S, McLaren S, Butler A, Martin S, Glodzik D, Menzies A, Raine K, Hinton J, Jones D, Mudie LJ, Jiang B, Vincent D, Greene-Colozzi A, Adnet PY, Fatima A, Maetens M, Ignatiadis M, Stratton MR, Sotiriou C, Richardson AL, Lønning PE, Wedge DC, Campbell PJ
Year : 2015
Journal : Nat. Med.
Volume : 21(7)
Pages : 751-9

Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab: A Secondary Analysis of the NeoALTTO Trial.

Authors : Salgado R, Denkert C, Campbell C, Savas P, Nucifero P, Aura C, de Azambuja E, Eidtmann H, Ellis CE, Baselga J, Piccart-Gebhart M, Michiels S, Bradbury I, Sotiriou C, Loi S
Year : 2015
Journal : JAMA Oncol
Volume : 1(4)
Pages : 448-54

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells.

Authors : Ju YS, Tubio JM, Mifsud W, Fu B, Davies HR, Ramakrishna M, Li Y, Yates L, Gundem G, Tarpey PS, Behjati S, Papaemmanuil E, Martin S, Fullam A, Gerstung M, Nangalia J, Green AR, Caldas C, Borg Å, Tutt A, Lee MT, van t Veer LJ, Tan BK, Aparicio S, Span PN, Martens JW, Knappskog S, Vincent-Salomon A, Borresen-Dale AL, Eyfjord JE, Flanagan AM, Foster C, Neal DE, Cooper C, Eeles R, Lakhani SR, Desmedt C, Thomas G, Richardson AL, Purdie CA, Thompson AM, McDermott U, Yang F, Nik-Zainal S, Campbell PJ, Stratton MR
Year : 2015
Journal : Genome Res
Volume : 25(6)
Pages : 814-24

Transfer of clinically relevant gene expression signatures in breast cancer: from Affymetrix microarray to Illumina RNA-Sequencing technology.

Authors : Fumagalli D, Blanchet-Cohen A, Brown D, Desmedt C, Gacquer D, Michiels S, Rothé F, Majjaj S, Salgado R, Larsimont D, Ignatiadis M, Maetens M, Piccart-Gebhart M, Detours V, Sotiriou C, Haibe-Kains B
Year : 2014
Journal : BMC Genomics
Volume : 15(1)
Pages : 1008

Deciphering clonality in aneuploid tumors using SNP array and sequencing data.

Authors : Lönnstedt IM, Caramia F, Li J, Fumagalli D, Salgado R, Rowan A, Salm M, Kanu N, Savas P, Horswell S, Gade S, Loibl S, Neven P, Sotiriou C, Swanton C, Loi S, Speed TP
Year : 2014
Journal : Genome Biol.
Volume : 15(9)
Pages : 470

Is the differentiation into molecular subtypes of breast cancer important for staging, local and systemic therapy, and follow up?

Authors : Sonnenblick A, Fumagalli D, Sotiriou C, Piccart-Gebhart M
Year : 2014
Journal : Cancer Treat Rev
Volume : 40(9)
Pages : 1089-95

PIK3CA mutations are associated with lower rates of pathologic complete response to anti-human epidermal growth factor receptor 2 (her2) therapy in primary HER2-overexpressing breast cancer.

Authors : Loibl S, Von Minckwitz G, Schneeweiss A, Paepke S, Lehmann A, Rezai M, Zahm DM, Sinn P, Khandan F, Eidtmann H, Dohnal K, Heinrichs C, Huober J, Pfitzner B, Fasching PA, Andre F, Lindner JL, Sotiriou C, Dykgers A, Guo S, Gade S, Nekljudova V, Loi S, Untch M, Denkert C
Year : 2014
Journal : J. Clin. Oncol.
Volume : 32(29)
Pages : 3212-20

New Strategies in Breast Cancer: The Significance of Molecular Subtypes in Systemic Adjuvant Treatment for Small T1a,bN0M0 Tumors.

Authors : Sonnenblick A, Fumagalli D, Azim HA, Sotiriou C, Piccart-Gebhart M
Year : 2014
Journal : Clin Cancer Res
Volume : 20(24)
Pages : 6242-6

The AURORA initiative for metastatic breast cancer.

Authors : Zardavas D, Maetens M, Irrthum A, Goulioti T, Engelen K, Fumagalli D, Salgado R, Aftimos P, Saini KS, Sotiriou C, Campbell P, Dinh P, Von Minckwitz G, Gelber Rd, Dowsett M, Di Leo A, Cameron D, Baselga J, Gnant M, Goldhirsch A, Norton L, Piccart-Gebhart M
Year : 2014
Journal : Br J Cancer
Volume : 111(10)
Pages : 1881-7

Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancer.

Authors : Rothé F, Laes JF, Lambrechts D, Smeets D, Vincent D, Maetens M, Fumagalli D, Michiels S, Drisis S, Moerman C, Detiffe JP, Larsimont D, Awada A, Piccart-Gebhart M, Sotiriou C, Ignatiadis M
Year : 2014
Journal : Ann Oncol
Volume : 25(10)
Pages : 1959-65

Regulation of DNA Methylation Patterns by CK2-Mediated Phosphorylation of Dnmt3a.

Authors : Deplus R, Blanchon L, Rajavelu A, Boukaba A, Defrance M, Luciani J, Rothé F, Dedeurwaerder S, Denis H, Brinkman AB, Simmer F, Müller F, Bertin B, Berdasco M, Putmans P, Calonne E, Litchfield DW, de Launoit Y, Jurkowski TP, Stunnenberg HG, Bock C, Sotiriou C, Fraga MF, Esteller M, Jeltsch A, Fuks F
Year : 2014
Journal : Cell Rep
Volume : 8(3)
Pages : 743-753

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

Authors : Tubio JM, Li Y, Ju YS, Martincorena I, Cooke SL, Tojo M, Gundem G, Pipinikas CP, Zamora J, Raine K, Menzies A, Roman-Garcia P, Fullam A, Gerstung M, Shlien A, Tarpey PS, Papaemmanuil E, Knappskog S, Van Loo P, Ramakrishna M, Davies HR, Wedge DC, Teague JW, Butler AP, Nik-Zainal S, Alexandrov L, Behjati S, Yates LR, Bolli N, Mudie L, Hardy C, Martin S, McLaren S, + collaborators (among others :, Larsimont D, Desmedt C, Sotiriou C, Campbell PJ
Year : 2014
Journal : Science
Volume : 345(6196)
Pages : 1251343