Articles scientifiques

Identification of Acute Myeloid Leukemia Bone Marrow Circulating MicroRNAs.

Auteurs : Moussa Agha D, Rouas R, Najar M, Bouhtit F, Naamane N, Fayyad-Kazan H, Bron D, Meuleman N, Lewalle P, Merimi M
Année : 2020
Journal : Int J Mol Sci
Volume : 21

Importance of Crosstalk Between Chronic Lymphocytic Leukemia Cells and the Stromal Microenvironment: Direct Contact, Soluble Factors, and Extracellular Vesicles.

Auteurs : Dubois N, Crompot E, Meuleman N, Bron D, Lagneaux L, Stamatopoulos B
Année : 2020
Journal : Front Oncol
Volume : 10
Pages : 1422

Impact of Bone Marrow miR-21 Expression on Acute Myeloid Leukemia T Lymphocyte Fragility and Dysfunction.

Auteurs : Moussa Agha D, Rouas R, Najar M, Bouhtit F, Fayyad-Kazan H, Lagneaux L, Bron D, Meuleman N, Lewalle P, Merimi M
Année : 2020
Journal : Cells
Volume : 9

An Improved Sequencing-Based Bioinformatics Pipeline to Track the Distribution and Clonal Architecture of Proviral Integration Sites.

Auteurs : Rosewick N, Hahaut V, Durkin K, Artesi M, Karpe S, Wayet J, Griebel P, Arsic N, Marçais A, Hermine O, Burny A, Georges M, Van den Broeke A
Année : 2020
Journal : Front Microbiol
Volume : 11
Pages : 587306

Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells.

Auteurs : Gómez-Aleza C, Nguyen B, Yoldi G, Ciscar M, Barranco A, Hernández-Jiménez E, Maetens M, Salgado R, Zafeiroglou M, Pellegrini P, Venet D, Garaud S, Trinidad EM, Benítez S, Vuylsteke P, Polastro L, Wildiers H, Simon P, Lindeman G, Larsimont D, Van den Eynden G, Velghe C, Rothé F, Willard-Gallo K, Michiels S, Muñoz P, Walzer T, Planelles L, Penninger J, Azim HA Jr, Loi S, Piccart-Gebhart M, Sotiriou C, González-Suárez E
Année : 2020
Journal : Nat Commun
Volume : 11
Pages : 6335

Chimeric antigen receptor T-cell lymphoma immunotherapy: the next questions.

Auteurs : Salaroli A, Spilleboudt C, Bron D, Lewalle P
Année : 2020
Journal : Curr Opin Oncol
Volume : 32
Pages : 434-441

COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus.

Auteurs : Scarfò L, Chatzikonstantinou T, Rigolin GM, Quaresmini G, Motta M, Vitale C, Garcia-Marco JA, Hernández-Rivas JÁ, Mirás F, Baile M, Marquet J, Niemann CU, Reda G, Munir T, Gimeno E, Marchetti M, Quaglia FM, Varettoni M, Delgado J, Iyengar S, Janssens A, Marasca R, Ferrari A, Cuéllar-García C, Itchaki G, Špaček M, De Paoli L, Laurenti L, Levin MD, Lista E, Mauro FR, Šimkovič M, Van Der Spek E, Vandenberghe E, Trentin L, Wasik-Szczepanek E, Ruchlemer R, Bron D, De Paolis MR, Del Poeta G, Farina L, Foglietta M, Gentile M, Herishanu Y, Herold T, Jaksic O, Kater AP, Kersting S, Malerba L, Orsucci L, Popov VM, Sportoletti P, Yassin M, Pocali B, Barna G, Chiarenza A, Dos Santos G, Nikitin E, Andres M, Dimou M, Doubek M, Enrico A, Hakobyan Y, Kalashnikova O, Ortiz Pareja M, Papaioannou M, Rossi D, Shah N, Shrestha A, Stanca O, Stavroyianni N, Strugov V, Tam C, Zdrenghea M, Coscia M, Stamatopoulos K, Rossi G, Rambaldi A, Montserrat E, Foà R, Cuneo A, Ghia P
Année : 2020
Journal : Leukemia
Volume : 34
Pages : 2354-2363

Aging of Bone Marrow Mesenchymal Stromal Cells: Hematopoiesis Disturbances and Potential Role in the Development of Hematologic Cancers.

Auteurs : Massaro F, Corrillon F, Stamatopoulos B, Meuleman N, Lagneaux L, Bron D
Année : 2020
Journal : Cancers (Basel)
Volume : 13

Long-term follow-up of a trial comparing post-remission treatment with autologous or allogeneic bone marrow transplantation or intensive chemotherapy in younger acute myeloid leukemia patients.

Auteurs : Baron F, Efficace F, Cannella L, Willemze R, Vignetti M, Muus P, Marie JP, Ferrero D, Fazi P, La Sala E, Bourhis JH, Fabbiano F, Bosi A, Sborgia M, Martinelli G, Wittnebel S, Trisolini S, Petti MC, Halkes CJM, van der Velden WJFM, de Witte T, Amadori S, Zittoun RA, Suciu S
Année : 2020
Journal : Haematologica
Volume : 105
Pages : e13-e16

COVID-19, impact on myeloma patients.

Auteurs : Dufour I, Raedemaeker J, Andreozzi F, Verstraete G, Bailly S, Delforge M, Storms P, Jacquy C, Van de Velde A, Mineur P, Lejeune M, Bauwens D, Van Obbergh F, Kentos A, Nguyen J, Fostier K, De Weweire A, Meuleman N, Vekemans MC
Année : 2020
Journal : Ann Hematol
Volume : 99
Pages : 1947-1949

Selinexor in patients with relapsed or refractory diffuse large B-cell lymphoma (SADAL): a single-arm, multinational, multicentre, open-label, phase 2 trial.

Auteurs : Kalakonda N, Maerevoet M, Cavallo F, Follows G, Goy A, Vermaat JSP, Casasnovas O, Hamad N, Zijlstra JM, Bakhshi S, Bouabdallah R, Choquet S, Gurion R, Hill B, Jaeger U, Sancho JM, Schuster M, Thieblemont C, De la Cruz F, Egyed M, Mishra S, Offner F, Vassilakopoulos TP, Warzocha K, McCarthy D, Ma X, Corona K, Saint-Martin JR, Chang H, Landesman Y, Joshi A, Wang H, Shah J, Shacham S, Kauffman M, Van Den Neste E, Canales MA
Année : 2020
Journal : Lancet Haematol
Volume : 7
Pages : e511-e522

Mesenchymal Stem/Stromal Cells in Immunity and Disease: A Better Understanding for an Improved Use.

Auteurs : Merimi M, Lagneaux L, Moussa Agha D, Lewalle P, Meuleman N, Burny A, Fahmi H, Najar M
Année : 2020
Journal : J Clin Med
Volume : 9

Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials.

Auteurs : Hudecek J, Voorwerk L, van Seijen M, Nederlof I, de Maaker M, van den Berg J, van de Vijver KK, Sikorska K, Adams S, Demaria S, Viale G, Nielsen TO, Badve SS, Michiels S, Symmans WF, Sotiriou C, Rimm DL, Hewitt SM, Denkert C, Loibl S, Loi S, Bartlett JMS, Pruneri G, Dillon DA, Cheang MCU, Tutt A, Hall JA, Kos Z, Salgado R, Kok M, Horlings HM, + collaborators (among others :, Larsimont D
Année : 2020
Journal : NPJ Breast Cancer
Volume : 6
Pages : 15

Human CD8+ CD25+ CD127 low regulatory T cells: microRNA signature and impact on TGF-ß and IL-10 expression.

Auteurs : Rouas R, Merimi M, Najar M, El Zein N, Fayyad-Kazan M, Berehab M, Agha D, Bron D, Burny A, Rachidi W, Badran B, Lewalle P, Fayyad-Kazan H
Année : 2019
Journal : J Cell Physiol
Volume : 234
Pages : 17459-17472

Immunotherapy Associated Pulmonary Toxicity: Biology Behind Clinical and Radiological Features.

Auteurs : Porcu M, De Silva P, Solinas C, Battaglia A, Schena M, Scartozzi M, Bron D, Suri JS, Willard-Gallo K, Sangiolo D, Saba L
Année : 2019
Journal : Cancers (Basel)
Volume : 11

Pooled CRISPR Inverse PCR sequencing (PCIP-seq): simultaneous sequencing of retroviral insertion points and the associated provirus in thousands of cells with long reads.

Auteurs : Artesi M, Hahaut V, Cole B, Lambrechts L, Ashrafi F, Marcais A, Hermine O, Griebel P, Arsic N, van der Meer L, Burny A, Bron D, Bianchi F, Delvenne P, Bours V, Charlier C, Georges M, Vandekerckhove L, Van den Broeke A, Durkin K
Année : 2019
Journal : bioRxiv
Volume : _
Pages : 558130

The clinical use of circulating tumor cells (CTCs) enumeration for staging of metastatic breast cancer (MBC): International expert consensus paper.

Auteurs : Cristofanilli M, Pierga JY, Reuben J, Rademaker A, Davis AA, Peeters DJ, Fehm T, Nolé F, Gisbert-Criado R, Mavroudis D, Grisanti S, Giuliano M, Garcia-Saenz JA, Stebbing J, Caldas C, Gazzaniga P, Manso L, Zamarchi R, de Lascoiti AF, De Mattos-Arruda L, Ignatiadis M, Cabel L, Van Laere SJ, Meier-Stiegen F, Sandri MT, Vidal-Martinez J, Politaki E, Consoli F, Generali D, Cappelletti MR, Diaz-Rubio E, Krell J, Dawson SJ, Raimondi C, Rutten A, Janni W, Munzone E, Carañana V, Agelaki S, Almici C, Dirix L, Solomayer EF, Zorzino L, Darrigues L, Reis-Filho JS, Gerratana L, Michiels S, Bidard FC, Pantel K
Année : 2019
Journal : Crit Rev Oncol Hematol
Volume : 134
Pages : 39-45

Adult T-cell leukaemia-lymphoma: Pathogeny and clinical recommendations.

Auteurs : Vercruyssen M, Van den Broeke A, Salaroli A, Nguyen P, de Wind A, Meuleman N, Bron D
Année : 2019
Journal : Belgian J Hematology
Volume : 10
Pages : 277-284

Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients.

Auteurs : Chi VLD, Garaud S, De Silva P, Thibaud V, Stamatopoulos B, Berehad M, Gu-Trantien C, Krayem M, Duvillier H, Lodewyckx JN, Willard-Gallo K, Sibille C, Bron D
Année : 2019
Journal : BMC Cancer
Volume : 19
Pages : 81

Providing both autologous and allogeneic hematopoietic stem cell transplants (HSCT) may have a stronger impact on the outcome of autologous HSCT in adult patients than activity levels or implementation of JACIE at Belgian transplant centres.

Auteurs : Poirel HA, Vanspauwen M, Macq G, De Geyndt A, Maertens J, Willems E, Selleslag D, Poiré X, Theunissen K, Graux C, Kerre T, Zachée P, Meuleman N, De Becker A, Verlinden A, Van Obbergh F, Schuermans C, de Wilde V, Jaspers A, Pranger D, Deeren D, van Riet I, Vaes E, Beguin Y
Année : 2019
Journal : Bone Marrow Transplant
Volume : 54
Pages : 1434-1442