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 Articles scientifiques

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group.

Auteurs : El Bairi K, Haynes HR, Blackley E, Fineberg S, Shear J, Turner S, de Freitas JR, Sur D, Amendola LC, Gharib M, Kallala A, Arun I, Azmoudeh-Ardalan F, Fujimoto L, Sua LF, Liu SW, Lien HC, Kirtani P, Balancin M, El Attar H, Guleria P, Yang W, Shash E, Chen IC, Bautista V, Do Prado Moura JF, Rapoport BL, Castaneda C, Spengler E, Acosta-Haab G, Frahm I, Sanchez J, Castillo M, Bouchmaa N, Md Zin RR, Shui R, Onyuma T, Husain Z, Willard-Gallo K, Coosemans A, Perez EA, Provenzano E, Ericsson PG, Richardet E, Mehrotra R, Sarancone S, Ehinger A, Rimm DL, Bartlett JMS, Viale G, Denkert C, Hida AI, Sotiriou C, Loibl S, Hewitt SM, Badve S, Symmans WF, Kim RS, Pruneri G, Goel S, Francis PA, Inurrigarro G, Yamaguchi R, Garcia-Rivello H, Horlings H, Afqir S, Salgado R, Adams S, Kok M, Dieci MV, Michiels S, Demaria S, Loi S
Année : 2021
Journal : NPJ Breast Cancer
Volume : 7
Pages : 150

Functional Th1-oriented T follicular helper cells that infiltrate human breast cancer promote effective adaptive immunity.

Auteurs : Noël G, Fontsa ML, Garaud S, De Silva P, de Wind A, Van den Eynden GG, Salgado R, Boisson A, Locy H, Thomas N, Solinas C, Migliori E, Naveaux C, Duvillier H, Lucas S, Craciun L, Thielemans K, Larsimont D, Willard-Gallo K
Année : 2021
Journal : J Clin Invest
Volume : 131

Persistent anti-tumor response in cancer patients experiencing pneumonitis related to immune checkpoint blockade.

Auteurs : Belcaid L, Garaud S, Kerger J, Spyridon S, Aspeslagh S
Année : 2021
Journal : Acta Clin Belg
Volume : 76
Pages : 144-148

RNA Based Approaches to Profile Oncogenic Pathways From Low Quantity Samples to Drive Precision Oncology Strategies.

Auteurs : van de Stolpe A, Verhaegh W, Blay JY, Ma CX, Pauwels P, Pegram M, Prenen H, De Ruysscher D, Saba NF, Slovin SF, Willard-Gallo K, Husain H
Année : 2021
Journal : Front Genet
Volume : 11
Pages : 598118

Targeting CTLA-4 in cancer: Is it the ideal companion for PD-1 blockade immunotherapy combinations?

Auteurs : De Silva P, Aiello M, Gu-Trantien C, Migliori E, Willard-Gallo K, Solinas C
Année : 2021
Journal : Int J Cancer
Volume : 149
Pages : 31-41

Luminal Breast Cancer: Risk of Recurrence and Tumor-Associated Immune Suppression.

Auteurs : Pellegrino B, Hlavata Z, Migali C, De Silva P, Aiello M, Willard-Gallo K, Musolino A, Solinas C
Année : 2021
Journal : Mol Diagn Ther
Volume : 25
Pages : 409-424

Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell Activation.

Auteurs : Prat M, Salon M, Allain T, Dubreuil O, Noël G, Preisser L, Jean B, Cassard L, Lemée F, Tabah-Fish I, Pipy B, Jeannin P, Prost JF, Barret JM, Coste A
Année : 2021
Journal : Cancers (Basel)
Volume : 13

Heparanase: a potential marker of worse prognosis in estrogen receptor-positive breast cancer.

Auteurs : Zahavi T, Salmon-Divon M, Salgado R, Elkin M, Hermano E, Rubinstein AM, Francis PA, Di Leo A, Viale G, de Azambuja E, Ameye L, Sotiriou C, Salmon A, Kravchenko-Balasha N, Sonnenblick A
Année : 2021
Journal : NPJ Breast Cancer
Volume : 7
Pages : 67

Neo-CheckRay: radiation therapy and adenosine pathway blockade to increase benefit of immuno-chemotherapy in early stage luminal B breast cancer, a randomized phase II trial.

Auteurs : De Caluwe A, Buisseret L, Poortmans P, Van Gestel D, Salgado R, Sotiriou C, Larsimont D, Paesmans M, Craciun L, Drisis S, Vandekerckhove C, Reyal F, Veys I, Eiger D, Piccart-Gebhart M, Romano E, Ignatiadis M
Année : 2021
Journal : BMC Cancer
Volume : 21
Pages : 899

Tumour-infiltrating lymphocytes in non-invasive breast cancer: A systematic review and meta-analysis.

Auteurs : Caparica R, Bruzzone M, Agostinetto E, Franzoi MA, Ceppi M, Radosevic-Robin N, Penault-Llorca F, Willard-Gallo K, Loi S, Salgado R, de Azambuja E
Année : 2021
Journal : Breast
Volume : 59
Pages : 183-192

Copy Number Aberration Analysis to Predict Response to Neoadjuvant Anti-HER2 Therapy: Results from the NeoALTTO Phase III Clinical Trial.

Auteurs : Venet D, Rediti M, Maetens M, Fumagalli D, Brown DN, Majjaj S, Salgado R, Pusztai L, Harbeck N, El-Abed S, Wang Y, Saura C, Gomez H, Semiglazov VF, de Azambuja E, Huober J, Nuciforo P, Di Cosimo S, Piccart-Gebhart M, Loi S, Rothé F, Sotiriou C
Année : 2021
Journal : Clin Cancer Res
Volume : 27
Pages : 5607-5618

B cells and cancer.

Auteurs : Engelhard V, Conejo-Garcia JR, Ahmed R, Nelson BH, Willard-Gallo K, Bruno TC, Fridman WH
Année : 2021
Journal : Cancer Cell
Volume : 39
Pages : 1293-1296

Fluorescent Multiplex Immunohistochemistry Coupled With Other State-Of-The-Art Techniques to Systematically Characterize the Tumor Immune Microenvironment.

Auteurs : Boisson A, Noël G, Saiselet M, Rodrigues-Vitória J, Thomas N, Fontsa ML, Sofronii D, Naveaux C, Duvillier H, Craciun L, Larsimont D, Awada A, Detours V, Willard-Gallo K, Garaud S
Année : 2021
Journal : Front Mol Biosci
Volume : 8
Pages : 673042

A review of immune checkpoint blockade in breast cancer.

Auteurs : Pellegrino B, Tommasi C, Cursio OE, Musolino A, Migliori E, De Silva P, Senevirathne TH, Schena M, Scartozzi M, Farci D, Willard-Gallo K, Solinas C
Année : 2021
Journal : Semin Oncol
Volume : 48
Pages : 208-225

A Pathologist-Annotated Dataset for Validating Artificial Intelligence: A Project Description and Pilot Study.

Auteurs : Dudgeon SN, Wen S, Hanna MG, Gupta R, Amgad M, Sheth M, Marble H, Huang R, Herrmann MD, Szu CH, Tong D, Werness B, Szu E, Larsimont D, Madabhushi A, Hytopoulos E, Chen W, Singh R, Hart SN, Sharma A, Saltz J, Salgado R, Gallas BD
Année : 2021
Journal : J Pathol Inform
Volume : 12
Pages : 45

The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice.

Auteurs : Gonzalez-Ericsson PI, Stovgaard ES, Sua LF, Reisenbichler E, Kos Z, Carter JM, Michiels S, Le Quesne J, Nielsen TO, Lænkholm AV, Fox SB, Adam J, Bartlett JM, Rimm DL, Quinn C, Peeters D, Dieci MV, Vincent-Salomon A, Cree I, Hida AI, Balko JM, Haynes HR, Frahm I, Acosta-Haab G, Balancin M, Bellolio E, Yang W, Kirtani P, Sugie T, Ehinger A, Castaneda CA, Kok M, McArthur H, Siziopikou K, Badve S, Fineberg S, Gown A, Viale G, Schnitt SJ, Pruneri G, Penault-Llorca F, Hewitt S, Thompson EA, Allison KH, Symmans WF, Bellizzi AM, Brogi E, Moore DA, Larsimont D, Dillon DA, Lazar A, Lien H, Goetz MP, Broeckx G, El Bairi K, Harbeck N, Cimino-Mathews A, Sotiriou C, Adams S, Liu SW, Loibl S, Chen IC, Lakhani SR, Juco JW, Denkert C, Blackley EF, Demaria S, Leon-Ferre R, Gluz O, Zardavas D, Emancipator K, Ely S, Loi S, Salgado R, Sanders M
Année : 2020
Journal : J Pathol
Volume : 250
Pages : 667-684

The 2019 World Health Organization classification of tumours of the breast.

Auteurs : Tan PH, Ellis I, Allison K, Brogi E, Fox SB, Lakhani S, Lazar AJ, Morris EA, Sahin A, Salgado R, Sapino A, Sasano H, Schnitt S, Sotiriou C, van Diest P, White VA, Lokuhetty D, Cree IA
Année : 2020
Journal : Histopathology
Volume : 77
Pages : 181-185

Immune Checkpoint Inhibitor-Induced Pancreatic Injury: Imaging Findings and Literature Review.

Auteurs : Porcu M, Solinas C, Migali C, Battaglia A, Schena M, Mannelli L, Addeo A, Willard-Gallo K, Saba L
Année : 2020
Journal : Target Oncol
Volume : 15
Pages : 25-35

Breast cancer vaccines: Heeding the lessons of the past to guide a path forward.

Auteurs : Solinas C, Aiello M, Migliori E, Willard-Gallo K, Emens LA
Année : 2020
Journal : Cancer Treat Rev
Volume : 84
Pages : 101947

Reactive stroma and trastuzumab resistance in HER2-positive early breast cancer.

Auteurs : Sonnenblick A, Salmon-Divon M, Salgado R, Dvash E, Pondé N, Zahavi T, Salmon A, Loibl S, Denkert C, Joensuu H, Ameye L, Van den Eynden G, Kellokumpu-Lehtinen PL, Azaria A, Loi S, Michiels S, Richard F, Sotiriou C
Année : 2020
Journal : Int J Cancer
Volume : 147
Pages : 266-276