Articles scientifiques

Imprint of parity and age at first pregnancy on the genomic landscape of subsequent breast cancer.

Auteurs : Nguyen B, Venet D, Lambertini M, Desmedt C, Salgado R, Horlings HM, Rothé F, Sotiriou C
Année : 2019
Journal : Breast Cancer Res
Volume : 21
Pages : 25

Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers.

Auteurs : Gruosso T, Gigoux M, Manem VSK, Bertos N, Zuo D, Perlitch I, Saleh SMI, Zhao H, Souleimanova M, Johnson RM, Monette A, Ramos VM, Hallett MT, Stagg J, Lapointe R, Omeroglu A, Meterissian S, Buisseret L, Van den Eynden G, Salgado R, Guiot MC, Haibe-Kains B, Park M
Année : 2019
Journal : J Clin Invest
Volume : 129
Pages : 1785-1800

Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients.

Auteurs : Chi VLD, Garaud S, De Silva P, Thibaud V, Stamatopoulos B, Berehad M, Gu-Trantien C, Krayem M, Duvillier H, Lodewyckx JN, Willard-Gallo K, Sibille C, Bron D
Année : 2019
Journal : BMC Cancer
Volume : 19
Pages : 81

The circular RNome of primary breast cancer.

Auteurs : Smid M, Wilting SM, Uhr K, Rodríguez-González FG, de Weerd V, Prager-Van der Smissen WJC, van der Vlugt-Daane M, van Galen A, Nik-Zainal S, Butler A, Martin S, Davies HR, Staaf J, Van de Vijver MJ, Richardson AL, Macgrogan G, Salgado R, Van den Eynden GGGM, Purdie CA, Thompson AM, Caldas C, Span PN, Sweep FCGJ, Simpson PT, Lakhani SR, Van Laere S, Desmedt C, Paradiso A, Eyfjord J, Broeks A, Vincent-Salomon A, Futreal AP, Knappskog S, King T, Viari A, Børresen-Dale AL, Stunnenberg HG, Stratton M, Foekens JA, Sieuwerts AM, Martens JWM
Année : 2019
Journal : Genome Res
Volume : 29
Pages : 356-366

Tumor-Infiltrating Lymphocytes and Prognosis: A Pooled Individual Patient Analysis of Early-Stage Triple-Negative Breast Cancers.

Auteurs : Loi S, Drubay D, Adams S, Pruneri G, Francis PA, Lacroix-Triki M, Joensuu H, Dieci MV, Badve S, Demaria S, Gray R, Munzone E, Lemonnier J, Sotiriou C, Piccart-Gebhart M, Kellokumpu-Lehtinen PL, Vingiani A, Gray K, Andre F, Denkert C, Salgado R, Michiels S
Année : 2019
Journal : J Clin Oncol
Volume : 37
Pages : 559-569

FOXP1 negatively regulates tumor infiltrating lymphocyte migration in human breast cancer.

Auteurs : De Silva P, Garaud S, Solinas C, de Wind A, Van den Eyden G, Jose V, Gu-Trantien C, Migliori E, Boisson A, Naveaux C, Duvillier H, Craciun L, Larsimont D, Piccart-Gebhart M, Willard-Gallo K
Année : 2019
Journal : EBioMedicine
Volume : 39
Pages : 226-238

Tumor-Infiltrating Lymphocytes in Patients Receiving Trastuzumab/Pertuzumab-Based Chemotherapy: A TRYPHAENA Substudy.

Auteurs : Ignatiadis M, Van den Eynden G, Roberto S, Fornili M, Bareche Y, Desmedt C, Rothé F, Maetens M, Venet D, Holgado E, McNally V, Kiermaier A, Savage HM, Wilson TR, Cortes J, Schneeweiss A, Willard-Gallo K, Biganzoli E, Sotiriou C
Année : 2019
Journal : J Natl Cancer Inst
Volume : 111
Pages : 69-77

Comprehensive evaluation of methods to assess overall and cell-specific immune infiltrates in breast cancer.

Auteurs : Nederlof I, De Bortoli D, Bareche Y, Nguyen B, de Maaker M, Hooijer GKJ, Buisseret L, Kok M, Smid M, Van den Eynden GGGM, Brinkman AB, Hudecek J, Koster J, Sotiriou C, Larsimont D, Martens JWM, Van de Vijver MJ, Horlings HM, Salgado R, Biganzoli E, Desmedt C
Année : 2019
Journal : Breast Cancer Res
Volume : 21
Pages : 151

Significance of TIM3 expression in cancer: From biology to the clinic.

Auteurs : Solinas C, De Silva P, Bron D, Willard-Gallo K, Sangiolo D
Année : 2019
Journal : Semin Oncol
Volume : 46
Pages : 372-379

Tumor Banks: A Quality Control Scheme Proposal.

Auteurs : Craciun L, Spinette SA, Rassy M, Salgado R, de Wind A, Demetter P, Verset L, Gomez Galdon M, Chintinne M, Sirtaine N, de St Aubain N, Laios I, Roy F, Larsimont D
Année : 2019
Journal : Front Med (Lausanne)
Volume : 6
Pages : 225

Tumor-Derived Thymic Stromal Lymphopoietin Expands Bone Marrow B-cell Precursors in Circulation to Support Metastasis.

Auteurs : Ragonnaud E, Moritoh K, Bodogai M, Gusev F, Garaud S, Chen C, Wang X, Baljinnyam T, Becker KG, Maul RW, Willard-Gallo K, Rogaev E, Biragyn A
Année : 2019
Journal : Cancer Res
Volume : 79
Pages : 5826-5838

Tumor infiltrating B-cells signal functional humoral immune responses in breast cancer.

Auteurs : Garaud S, Buisseret L, Solinas C, Gu-Trantien C, de Wind A, Van den Eynden G, Naveaux C, Lodewyckx JN, Boisson A, Duvillier H, Craciun L, Ameye L, Veys I, Paesmans M, Larsimont D, Piccart-Gebhart M, Willard-Gallo K
Année : 2019
Journal : JCI Insight
Volume : 5

LAG3: The Biological Processes That Motivate Targeting This Immune Checkpoint Molecule in Human Cancer.

Auteurs : Solinas C, Migliori E, De Silva P, Willard-Gallo K
Année : 2019
Journal : Cancers (Basel)
Volume : 11

Clinical significance of CD73 in triple-negative breast cancer: multiplex analysis of a phase III clinical trial.

Auteurs : Buisseret L, Pommey S, Allard B, Garaud S, Bergeron M, Cousineau I, Ameye L, Bareche Y, Paesmans M, Crown JPA, Di Leo A, Loi S, Piccart-Gebhart M, Willard-Gallo K, Sotiriou C, Stagg J
Année : 2018
Journal : Ann Oncol
Volume : 29(4)
Pages : 1056-62

p-STAT3 in luminal breast cancer: Integrated RNA-protein pooled analysis and results from the BIG 2-98 phase III trial.

Auteurs : Sonnenblick A, Salgado R, Brohée S, Zahavi T, Peretz T, Van den Eynden G, Rouas G, Salmon A, Francis PA, Di Leo A, Crown JPA, Viale G, Daly L, Javdan B, Fujisawa S, de Azambuja E, Ameye L, Piccart-Gebhart M, Bromberg JF, Sotiriou C
Année : 2018
Journal : Int J Oncol
Volume : 52(2)
Pages : 424-432

Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno-Oncology Biomarker Working Group o

Auteurs : Dieci MV, Radosevic-Robin N, Fineberg S, Van den Eynden G, Ternes N, Penault-Llorca F, Pruneri G, DAlfonso TM, Demaria S, Castaneda C, Sanchez J, Badve S, Michiels S, Bossuyt V, Rojo F, Singh B, Nielsen T, Viale G, Kim SR, Hewitt S, Wienert S, Loibl S, Rimm D, Symmans F, Denkert C, Adams S, Loi S, Salgado R
Année : 2018
Journal : Semin Cancer Biol
Volume : 52
Pages : 16-25

Inflammatory Stroma of Lymphoepithelioma-like Carcinoma of the Cervix: Immunohistochemical Study of 3 Cases and Review of the Literature.

Auteurs : Philippe A, Rassy M, Craciun L, Naveaux C, Willard-Gallo K, Larsimont D, Veys I
Année : 2018
Journal : Int J Gynecol Pathol
Volume : 37
Pages : 482-487

Antigen Specificity and Clinical Significance of IgG and IgA Autoantibodies Produced in situ by Tumor-Infiltrating B Cells in Breast Cancer.

Auteurs : Garaud S, Zayakin P, Buisseret L, Rulle U, Silina K, de Wind A, Van den Eyden G, Larsimont D, Willard-Gallo K
Année : 2018
Journal : Front Immunol
Volume : 9
Pages : 2660

Cancer immunotherapy-associated hypophysitis.

Auteurs : Solinas C, Porcu M, De Silva P, Musi M, Aspeslagh S, Scartozzi M, Willard-Gallo K, Mariotti S, Saba L
Année : 2018
Journal : Semin Oncol
Volume : 45
Pages : 181-186

Roadbook for the implementation of next-generation sequencing in clinical practice in oncology and hemato-oncology in Belgium.

Auteurs : Van Valckenborgh E, Hébrant A, Antoniou A, Van Hoof W, Van Bussel J, Pauwels P, Salgado R, Van Doren W, Waeytens A, Van den Bulcke M
Année : 2018
Journal : Arch Public Health
Volume : 76
Pages : 49