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Statut de l'essai
Trial Phase
Type d'essai
61 clinical trials grid list download
Body (indexed field) Identifiant (ID) Email
28624 1. moderate or severe cGVHD per NIH Consensus Criteria
2. KPS score > 60%.
3. Evidence of myeloid and platelet engraftment, that is, ANC > 1.0 × 10e9/L and platelet
count > 50 × 10e9/L.
4. Has not received more than 3 days/72 hours of systemic corticoster
Sebastian Wittnebel NA Incyte Corporate GRAVITAS-309 Trial closed A Phase 2/3 Study of Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease (GRAVITAS-309) Sebastian.Wittnebel@hubruxelles.be 2/3 2
22646 no suitable HLA-matched sibling or unrelated donor / no prior allogeneic stem cell transplantation/ AML, ALL or MDS Philippe Lewalle Multiple Kiadis Pharma HATCY study Trial closed A Phase III, multicenter, randomized controlled study to compare safety and efficacy of a haploidentical HSCT and adjunctive treatment with ATIR101, a T-lymphocyte enriched leukocyte preparation depleted ex vivo of host alloreactive T-cells, versus a haploidentical HSCT with post-transplant cyclophosphamide in patients with a hematologic malignancy philippe.lewalle@hubruxelles.be 3 3
28584 IDH1 or IDH2 +, fit for standard chemotherapy Sebastian Wittnebel Acute leukemia Hovon HOVON 150 AML/ AMLSG 29-18 Trial open for recruitment A phase 3, multicenter, double-blind, randomized, placebo-controlled study of ivosidenib or enasidenib in combination with induction therapy and consolidation therapy followed by maintenance therapy in patients with newly diagnosed acute myeloid leukemia or myelodysplastic syndrome with excess blasts-2, with an IDH1 or IDH2 mutation, respectively, eligible for intensive chemotherapy (HOVON 150 AML/ AMLSG 29-18) Sebastian.Wittnebel@hubruxelles.be 3 3
29135 Presence of the FLT3 mutation Adriano Salaroli Acute leukemia Hovon HOVON 156 AML / AMLSG 28-18 Trial closed for recruitment A phase 3, multicenter, open-label, randomized, study of gilteritinib versus midostaurin in combination with induction and consolidation therapy followed by one-year maintenance in patients with newly diagnosed Acute Myeloid Leukemia (AML) or Myelodysplastic syndromes with excess blasts-2 (MDS-EB2) with FLT3 mutations eligible for intensive chemotherapy adriano.salaroli@hubruxelles.be 3 3
22625 RECIST 1.1, after standard trerapy Ahmad Hussein Awada Multiple Lilly I7W-MC-JQBA Trial closed A Phase 1 Study of LY3127804 as Monotherapy and in Combination with Ramucirumab in Patients with Advanced Solid Tumors ahmad.awada@hubruxelles.be 1 1
22650 vaccine, diarrhea, clostridium Multiple Pfizer IJB_2672 Trial closed A Phase 3, Placebo-Controlled, Randomized, Observer-Blinded Study To Evaluate The Efficacy, Safety, And Tolerability Of A Clostridium Difficile Vaccine In Adults 50 Years Of Age And Older 3 3
22850 Metastatic, any tumors Solid tumors Institut Jules Bordet IJB_2728 Trial open for recruitment Improving emotion regulation for patients with metastatic cancer: A pilot study assessing the impact of a multi-component psychological group intervention
29771 RRMM: at least 2 prior lines of therapy with at least 2 consecutive cycles of a second or third generation immunomodulator (lenalidomide or pomalidomide), steroid (dexamethasone), proteasome inhibitor (bortezomib, carfilzoib, ixazomib) and anti-CD38 MoAb Multiple Sanofi-Aventis IJB_3627 Trial open for recruitment A First-in-human, open-label Phase 1/2 study to investigate safety and efficacy of SAR445514, an NK-cell engager (NKCE) targeting B-cell maturation antigen (BCMA) in monotherapy in participants with relapsed/refractory multiple myeloma (RRMM) and in relapsed/refractory light[1]chain amyloidosis (RRLCA) 1/2 1
29416 Documented diagnosis of MM with relapsed or refractory disease to at least two prior MM treatment regimens which should include exposure to IMiD (e.g., lenalidomide, pomalidomide) and PIs (e.g., bortezomib, carfilzomib, ixazomib) either alone or in combin Nathalie Meuleman Myeloma Celyad IMMUNICY-1 Trial closed An open-label phase I, multi-center study to determine the recommended dose of the chimeric antigen receptor T-cell treatment CYAD-211 after a non-myeloablative preconditioning chemotherapy in multiple myeloma patients with relapsed or refractory disease (IMMUNICY-1 - Immunotherapy for Multiple Myeloma with HLA-UNrestrIcted allogeneic CAR T-cell therapy CYAD-211) nathalie.meuleman@hubruxelles.be 1 1
22655 Any line Ahmad Hussein Awada Solid tumors Incyte Corporate INCB59872-101 Trial closed A Phase 1/2, Open-Label, Dose-Escalation / Dose-Expansion, Safety and Tolerability Study of INCB059872 in Subjects With Advanced Malignancies ahmad.awada@hubruxelles.be 1/2 1
22636 Under Iclusig regimen Philippe Lewalle Multiple Incyte Corporate Incyte-30006 Trial closed Prospective Registry of Iclusig(r) (Ponatinib) used in Clinical Practice for the Treatment of Patients with Chronic Myeloid Leukemia or Ph+ Acute Lymphoblastic Leukemia in Belgium philippe.lewalle@hubruxelles.be 4 4
22849 Be a parent or close relative of a child between the ages of 3 and 18 confronted with parental cancer, any tumors Solid tumors Intervention destinée aux parents Trial open for recruitment L'enfant face au cancer d'un parent: une étude randomisée évaluant l'efficacité d'une intervention psychologique destinée à soutenir la parentalité
22968 Christiane Jungels Multiple iTeos IO-002 Trial closed Phase I/IIa First-In_human Study of EOS884448 in Participants with Advanced Cancers christiane.jungels@hubruxelles.be 1/2 1
29650 Patients with RRMM who have received at least one prior line of therapy ; for whom the treating physician has made the decision to initiate isatuximab per routine practice and independently of the purpose of the study Nathalie Meuleman Myeloma Sanofi-Aventis IONA Trial open for recruitment A non-interventional, multinational, observational study with isatuximab in patients with relapsed and/or refractory multiple myeloma (RRMM)(OBS16577) IONA nathalie.meuleman@hubruxelles.be 4 4