Articles scientifiques

The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice.

Auteurs : Gonzalez-Ericsson PI, Stovgaard ES, Sua LF, Reisenbichler E, Kos Z, Carter JM, Michiels S, Le Quesne J, Nielsen TO, Lænkholm AV, Fox SB, Adam J, Bartlett JM, Rimm DL, Quinn C, Peeters D, Dieci MV, Vincent-Salomon A, Cree I, Hida AI, Balko JM, Haynes HR, Frahm I, Acosta-Haab G, Balancin M, Bellolio E, Yang W, Kirtani P, Sugie T, Ehinger A, Castaneda CA, Kok M, McArthur H, Siziopikou K, Badve S, Fineberg S, Gown A, Viale G, Schnitt SJ, Pruneri G, Penault-Llorca F, Hewitt S, Thompson EA, Allison KH, Symmans WF, Bellizzi AM, Brogi E, Moore DA, Larsimont D, Dillon DA, Lazar A, Lien H, Goetz MP, Broeckx G, El Bairi K, Harbeck N, Cimino-Mathews A, Sotiriou C, Adams S, Liu SW, Loibl S, Chen IC, Lakhani SR, Juco JW, Denkert C, Blackley EF, Demaria S, Leon-Ferre R, Gluz O, Zardavas D, Emancipator K, Ely S, Loi S, Salgado R, Sanders M
Année : 2020
Journal : J Pathol
Volume : 250
Pages : 667-684

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.

Auteurs : Bailey MH, Meyerson WU, Dursi LJ, Wang LB, Dong G, Liang WW, Weerasinghe A, Li S, Li Y, Kelso S, Saksena G, Ellrott K, Wendl MC, Wheeler DA, Getz G, Simpson JT, Gerstein MB, Ding L, + collaborators (among others :, Larsimont D
Année : 2020
Journal : Nat Commun
Volume : 11
Pages : 4748

Sex differences in oncogenic mutational processes.

Auteurs : Li CH, Prokopec SD, Sun RX, Yousif F, Schmitz N, Boutros PC, + collaborators (among others :, Larsimont D
Année : 2020
Journal : Nat Commun
Volume : 11
Pages : 4330

Long-term outcomes in patients with decompensated alcohol-related liver disease, steatohepatitis and Maddrey's discriminant function <32.

Auteurs : Degré D, Stauber RE, Englebert G, Sarocchi F, Verset L, Rainer F, Spindelboeck W, Njimi H, Trépo E, Gustot T, Lackner C, Deltenre P, Moreno C
Année : 2020
Journal : J Hepatol
Volume : 72
Pages : 636-642

Update on the pathology, genetics and somatic landscape of sebaceous tumours.

Auteurs : Ferreira I, Wiedemeyer K, Demetter P, Adams DJ, Arends MJ, Brenn T
Année : 2020
Journal : Histopathology
Volume : 76
Pages : 640-649

Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.

Auteurs : Bailey MH, Meyerson WU, Dursi LJ, Wang LB, Dong G, Liang WW, Weerasinghe A, Li S, Li Y, Kelso S, Saksena G, Ellrott K, Wendl MC, Wheeler DA, Getz G, Simpson JT, Gerstein MB, Ding L, + collaborators (among others :, Larsimont D
Année : 2020
Journal : Nat Commun
Volume : 11
Pages : 6232

A radical approach to achieve complete cytoreductive surgery improve survival of patients with advanced ovarian cancer.

Auteurs : Liberale G, Pop FC, Polastro L, Kerger J, Moreau M, Chintinne M, Larsimont D, Nogaret JM, Veys I
Année : 2020
Journal : J Visc Surg
Volume : 157
Pages : 79-86

Early prediction of neoadjuvant treatment outcome in locally advanced breast cancer using parametric response mapping and radial heterogeneity from breast MRI.

Auteurs : Drisis S, El Adoui M, Flamen P, Benjelloun M, de Wind R, Paesmans M, Ignatiadis M, Bali MA, Lemort M
Année : 2020
Journal : J Magn Reson Imaging
Volume : 51
Pages : 1403-1411

Unraveling Triple-Negative Breast Cancer Tumor Microenvironment Heterogeneity: Towards an Optimized Treatment Approach.

Auteurs : Bareche Y, Buisseret L, Gruosso T, Girard E, Venet D, Dupont F, Desmedt C, Larsimont D, Park M, Rothé F, Stagg J, Sotiriou C
Année : 2020
Journal : J Natl Cancer Inst
Volume : 112
Pages : 708-719

Extended time interval between diagnosis and surgery does not improve the outcome in patients operated for resection or ablation of breast cancer liver metastases.

Auteurs : Lucidi V, Bohlok A, Liberale G, Bez M, Germanova D, Bouazza F, Demetter P, Larsimont D, Aftimos P, Smoll NR, Donckier V
Année : 2020
Journal : Eur J Surg Oncol
Volume : 46
Pages : 229-234

ACE2 Protein Landscape in the Head and Neck Region: The Conundrum of SARS-CoV-2 Infection.

Auteurs : Descamps G, Verset L, Trelcat A, Hopkins C, Lechien JR, Journe F, Saussez S
Année : 2020
Journal : Biology (Basel)
Volume : 9

Feasibility and clinical impact of routine molecular testing of gastrointestinal cancers at a tertiary centre with a multi-gene, tumor-agnostic, next generation sequencing panel.

Auteurs : Bregni G, Sticca T, Camera S, Akin Telli T, Craciun L, Trevisi E, Pretta A, Kehagias P, Leduc S, Senti C, Deleporte A, Vandeputte C, Saad ED, Kerger J, Gil T, Piccart-Gebhart M, Awada A, Demetter P, Larsimont D, Hendlisz A, Aftimos P, Sclafani F
Année : 2020
Journal : Acta oncol (Stockholm)
Volume : 59
Pages : 1438-1446

[Comparison of the mismatch repair deficiency of colorectal cancers between African and European cohorts].

Auteurs : Bienfait L, Doukoure B, Verset L, Demetter P
Année : 2020
Journal : Ann Pathol
Volume : 40
Pages : 12-18

Indications of next-generation sequencing in non-Hodgkin's lymphoma.

Auteurs : Heimann P, Dewispelaere L
Année : 2020
Journal : Curr Opin Oncol
Volume : 32
Pages : 391-397

Prognostic impact of glioblastoma stem cell markers OLIG2 and CCND2.

Auteurs : Bouchart C, Trépant AL, Hein M, Van Gestel D, Demetter P
Année : 2020
Journal : Cancer Med
Volume : 9
Pages : 1069-1078

Infiltrative tumour growth pattern correlates with poor outcome in oesophageal cancer.

Auteurs : Anciaux M, Demetter P, de Wind R, Gomez Galdon M, Vande Velde S, Lens G, Craciun L, Deleruelle A, Larsimont D, Lenaerts T, Sclafani F, Deleporte A, Donckier V, Hendlisz A, Vandeputte C
Année : 2020
Journal : BMJ Open Gastroenterol
Volume : 7

A rare presentation of small diaphragmatic epidermoid cyst with extremely elevated serum CA19-9 level.

Auteurs : El-Khoury M, Bohlok A, Sleiman YA, Loi P, Coppens E, Demetter P, El Nakadi I
Année : 2020
Journal : Ann R Coll Surg Engl
Volume : 102
Pages : e23-e25

Farnesoid X receptor as marker of osteotropism of breast cancers through its role in the osteomimetism of tumor cells.

Auteurs : Absil L, Journe F, Larsimont D, Body JJ, Tafforeau L, Nonclercq D
Année : 2020
Journal : BMC Cancer
Volume : 20
Pages : 640

Fat density is a novel prognostic marker in patients with esophageal cancer.

Auteurs : Anciaux M, Van Gossum A, Wenglinski C, Ameye L, Guiot T, Flamen P, Demetter P, Deleporte A, Sclafani F, Donckier V, Hendlisz A, Vandeputte C
Année : 2020
Journal : Clin Nutr ESPEN
Volume : 39
Pages : 124-130

Systemic Sentinel Lymph Node Detection Using Fluorescence Imaging After Indocyanine Green Intravenous Injection in Colorectal Cancer: Protocol for a Feasibility Study.

Auteurs : Liberale G, Vankerckhove S, Bouazza F, Gomez Galdon M, Larsimont D, Moreau M, Bourgeois P, Donckier V
Année : 2020
Journal : JMIR Res Protoc
Volume : 9
Pages : e17976