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 Wetenschapelijke artikelen

Tumor-infiltrating lymphocyte composition, organization and PD-1/ PD-L1 expression are linked in breast cancer.

Auteurs : Buisseret L, Garaud S, de Wind A, Van den Eynden G, Boisson A, Solinas C, Gu-Trantien C, Naveaux C, Lodewyckx JN, Duvillier H, Craciun L, Veys I, Larsimont D, Piccart-Gebhart M, Stagg J, Sotiriou C, Willard-Gallo K
Jaar : 2016
Journal : Oncoimmunology
Volume : 6
Pagina's : e1257452

Langerhans cell number is a strong and independent prognostic factor for head and neck squamous cell carcinomas.

Auteurs : Kindt N, Descamps G, Seminerio I, Bellier J, Lechien JR, Pottier C, Larsimont D, Journe F, Delvenne P, Saussez S
Jaar : 2016
Journal : Oral Oncol
Volume : 62
Pagina's : 1-10

The Genomic Grade Assay Compared With Ki67 to Determine Risk of Distant Breast Cancer Recurrence.

Auteurs : Ignatiadis M, Azim HA Jr, Desmedt C, Veys I, Larsimont D, Salgado R, Lyng MB, Viale G, Leyland-Jones B, Giobbie-Hurder A, Kammler R, Dell orto P, Rothé F, Laïos I, Ditzel HJ, Regan MM, Piccart-Gebhart M, Michiels S, Sotiriou C
Jaar : 2016
Journal : JAMA Oncol
Volume : 2(2)
Pagina's : 217-24

Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome.

Auteurs : Fumagalli D, Gacquer D, Rothé F, Lefort A, Libert F, Brown D, Kheddoumi N, Shlien A, Konopka T, Salgado R, Larsimont D, Polyak K, Willard-Gallo K, Desmedt C, Piccart-Gebhart M, Abramowicz M, Campbell PJ, Sotiriou C, Detours V
Jaar : 2015
Journal : Cell Rep
Volume : 13
Pagina's : 277-89

Fluorescence imaging after intraoperative intravenous injection of indocyanine green for detection of lymph node metastases in colorectal cancer.

Auteurs : Liberale G, Vankerckhove S, Gomez Galdon M, Donckier V, Larsimont D, Bourgeois P
Jaar : 2015
Journal : Eur J Surg Oncol
Volume : 41(9)
Pagina's : 1256-60

Retrospective Rescreening of Negative Cervical Cytology Samples Preceding Histologically Proven CIN2-3 and Squamous Cell Carcinoma: An Educational Opportunity to Understand and Prevent Laboratory Errors.

Auteurs : Feoli F, Renard C, Abouyahia M, de Wind R, Larsimont D, Arbyn M
Jaar : 2015
Journal : Acta Cytol.
Volume : 59(3)
Pagina's : 265-72

SNPs at miR-155 binding sites of TYRP1 explain discrepancy between mRNA and protein and refine TYRP1 prognostic value in melanoma.

Auteurs : El Hajj P, Gilot D, Migault M, Theunis A, Van Kempen LC, Sales F, Fayyad-Kazan H, Badran B, Larsimont D, Awada A, Bachelot L, Galibert MD, Ghanem G, Journe F
Jaar : 2015
Journal : Br J Cancer
Volume : 113(1)
Pagina's : 91-8

Subclonal diversification of primary breast cancer revealed by multiregion sequencing.

Auteurs : Yates LR, Gerstung M, Knappskog S, Desmedt C, Gundem G, Van Loo P, Aas T, Alexandrov LB, Larsimont D, Davies H, Li Y, Ju YS, Ramakrishna M, Haugland HK, Lilleng PK, Nik-Zainal S, McLaren S, Butler A, Martin S, Glodzik D, Menzies A, Raine K, Hinton J, Jones D, Mudie LJ, Jiang B, Vincent D, Greene-Colozzi A, Adnet PY, Fatima A, Maetens M, Ignatiadis M, Stratton MR, Sotiriou C, Richardson AL, Lønning PE, Wedge DC, Campbell PJ
Jaar : 2015
Journal : Nat. Med.
Volume : 21(7)
Pagina's : 751-9

Revisiting the transcriptional analysis of primary tumours and associated nodal metastases with enhanced biological and statistical controls: application to thyroid cancer.

Auteurs : Tarabichi M, Saiselet M, Trésallet C, Hoang C, Larsimont D, Andry G, Maenhaut C, Detours V
Jaar : 2015
Journal : Br J Cancer
Volume : 112(10)
Pagina's : 1665-74

Uncovering the genomic heterogeneity of multifocal breast cancer.

Auteurs : Desmedt C, Fumagalli D, Pietri E, Zoppoli G, Brown D, Nik-Zainal S, Gundem G, Rothé F, Majjaj S, Garuti A, Carminati E, Loi S, Van Brussel T, Boeckx B, Maetens M, Mudie L, Vincent D, Kheddoumi N, Serra L, Massa I, Ballestrero A, Amadori D, Salgado R, de Wind A, Lambrechts D, Piccart-Gebhart M, Larsimont D, Campbell PJ, Sotiriou C
Jaar : 2015
Journal : J. Pathol.
Volume : 236(4)
Pagina's : 457-66

Predicting Anthracycline Benefit: TOP2A and CEP17-Not Only but Also.

Auteurs : Bartlett JM, McConkey CC, Munro AF, Desmedt C, Dunn JA, Larsimont D, O Malley FP, Cameron DA, Earl HM, Poole CJ, Shepherd LE, Cardoso F, Jensen MB, Caldas C, Twelves CJ, Rea DW, Ejlertsen B, Di Leo A, Pritchard KI
Jaar : 2015
Journal : J. Clin. Oncol.
Volume : 33(15)
Pagina's : 1680-7

No significant viral transcription detected in whole breast cancer transcriptomes.

Auteurs : Fimereli D, Gacquer D, Fumagalli D, Salgado R, Rothé F, Larsimont D, Sotiriou C, Detours V
Jaar : 2015
Journal : BMC Cancer
Volume : 15(null)
Pagina's : 147

Intratumor heterogeneity and clonal evolution in an aggressive PTC and matched metastases.

Auteurs : Le Pennec S, Konopka T, Gacquer D, Fimereli D, Tarabichi M, Tomás G, Savagner F, Decaussin-Petrucci M, Trésallet C, Andry G, Larsimont D, Detours V, Maenhaut C
Jaar : 2015
Journal : Endocr Relat Cancer
Volume : 22(2)
Pagina's : 205-16

Transfer of clinically relevant gene expression signatures in breast cancer: from Affymetrix microarray to Illumina RNA-Sequencing technology.

Auteurs : Fumagalli D, Blanchet-Cohen A, Brown D, Desmedt C, Gacquer D, Michiels S, Rothé F, Majjaj S, Salgado R, Larsimont D, Ignatiadis M, Maetens M, Piccart-Gebhart M, Detours V, Sotiriou C, Haibe-Kains B
Jaar : 2014
Journal : BMC Genomics
Volume : 15(1)
Pagina's : 1008

Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancer.

Auteurs : Rothé F, Laes JF, Lambrechts D, Smeets D, Vincent D, Maetens M, Fumagalli D, Michiels S, Drisis S, Moerman C, Detiffe JP, Larsimont D, Awada A, Piccart-Gebhart M, Sotiriou C, Ignatiadis M
Jaar : 2014
Journal : Ann Oncol
Volume : 25(10)
Pagina's : 1959-65

Infrared imaging in breast cancer: automated tissue component recognition and spectral characterization of breast cancer cells as well as the tumor microenvironment.

Auteurs : Benard A, Desmedt C, Smolina M, Szternfeld P, Verdonck M, Rouas G, Kheddoumi N, Rothé F, Larsimont D, Sotiriou C, Goormaghtigh E
Jaar : 2014
Journal : Analyst
Volume : 139(5)
Pagina's : 1044-56

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

Auteurs : Tubio JM, Li Y, Ju YS, Martincorena I, Cooke SL, Tojo M, Gundem G, Pipinikas CP, Zamora J, Raine K, Menzies A, Roman-Garcia P, Fullam A, Gerstung M, Shlien A, Tarpey PS, Papaemmanuil E, Knappskog S, Van Loo P, Ramakrishna M, Davies HR, Wedge DC, Teague JW, Butler AP, Nik-Zainal S, Alexandrov L, Behjati S, Yates LR, Bolli N, Mudie L, Hardy C, Martin S, McLaren S, + collaborators (among others :, Larsimont D, Desmedt C, Sotiriou C, Campbell PJ
Jaar : 2014
Journal : Science
Volume : 345(6196)
Pagina's : 1251343

Early invasive cancer and partial intraoperative electron radiation therapy of the breast: experience of the jules bordet institute.

Auteurs : Philippson C, Simon S, Vandekerkhove C, Hertens D, Veys I, Noterman D, De Neubourg F, Larsimont D, Bourgeois P, Van Houtte P, Nogaret JM
Jaar : 2014
Journal : Int J Breast Cancer
Volume : 2014
Pagina's : 627352

Processed pseudogenes acquired somatically during cancer development.

Auteurs : Cooke SL, Shlien A, Marshall J, Pipinikas CP, Martincorena I, Tubio JM, Li Y, Menzies A, Mudie L, Ramakrishna M, Yates L, Davies H, Bolli N, Bignell GR, Tarpey PS, Behjati S, Nik-Zainal S, Papaemmanuil E, Teixeira VH, Raine K, + collaborators (among others :, Larsimont D, Campbell PJ
Jaar : 2014
Journal : Nat Commun
Volume : 5(null)
Pagina's : 3644

Prognostic, predictive abilities and concordance of BCL2 and TP53 protein expression in primary breast cancers and axillary lymph-nodes: A retrospective analysis of the Belgian three arm study evaluating anthracycline vs CMF adjuvant chemotherapy.

Auteurs : Bozovic-Spasojevic I, Ameye L, Paesmans M, Larsimont D, Di Leo A, Dolci S, Piccart-Gebhart M, de Azambuja E, Loi S
Jaar : 2014
Journal : Breast
Volume : 23(4)
Pagina's : 473-81