Articles scientifiques

Progression-free survival as surrogate endpoint for overall survival in clinical trials of HER2-targeted agents in HER2-positive metastatic breast cancer.

Auteurs : Michiels S, Pugliano L, Marguet S, Grun D, Barinoff J, Cameron D, Cobleigh M, Di Leo A, Johnston S, Gasparini G, Kaufman B, Marty M, Nekjudova V, Paluch-Shimon S, Penault-Llorca F, Slamon D, Vogel C, Von Minckwitz G, Buyse M, Piccart-Gebhart M
Année : 2016
Journal : Ann Oncol
Volume : 27(6)
Pages : 1029-34

The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.

Auteurs : Van Kempen LC, Redpath M, Elchebly M, Klein KO, Papadakis AI, Wilmott JS, Scolyer RA, Edqvist PH, Pontén F, Schadendorf D, van Rijk AF, Michiels S, Dumay A, Helbling-Leclerc A, Dessen P, Wouters J, Stass M, Greenwood CM, Ghanem G, van den Oord J, Feunteun J, Spatz A
Année : 2016
Journal : Sci Transl Med
Volume : 8
Pages : 369ra177

Improved Survival of Calreticulin-Mutated Patients Compared With Janus Kinase 2 in Primary Myelofibrosis: A Meta-Analysis.

Auteurs : Kourie HR, Ameye L, Paesmans M, Bron D
Année : 2016
Journal : Clin Lymphoma Myeloma Leuk
Volume : 16(5)
Pages : 264-8

Serum free light chains should be the target of response evaluation in light chain multiple myeloma rather than urines.

Auteurs : Dejoie T, Corre J, Caillon H, Hulin C, Perrot A, Caillot D, Boyle E, Chretien ML, Fontan J, Belhadj K, Brechignac S, Decaux O, Voillat L, Rodon P, Fitoussi O, Araujo C, Benboubker L, Fontan C, Tiab M, Godmer P, Luycx O, Allangba O, Pignon JM, Fuzibet JG, Legros L, Stoppa AM, Dib M, Pegourie B, Orsini-Piocelle F, Karlin L, Arnulf B, Roussel M, Garderet L, Mohty M, Meuleman N, Doyen C, Lenain P, Macro M, Leleu X, Facon T, Moreau P, Attal M, Avet-Loiseau H
Année : 2016
Journal : Blood
Volume : 128(25)
Pages : 2941-48

Mesenchymal stromal cells from the foreskin: Tissue isolation, cell characterization and immunobiological properties.

Auteurs : Najar M, Raicevic G, André T, Fayyad-Kazan H, Pieters K, Bron D, Toungouz M, Lagneaux L
Année : 2016
Journal : Cytotherapy
Volume : 18
Pages : 320-35

Somatic mutation, copy number and transcriptomic profiles of primary and matched metastatic estrogen receptor-positive breast cancers.

Auteurs : Fumagalli D, Wilson TR, Salgado R, Lu X, Yu J, OBrien C, Walter K, Huw LY, Criscitiello C, Laios I, Jose V, Brown DN, Rothé F, Maetens M, Zardavas D, Savas P, Larsimont D, Piccart-Gebhart M, Michiels S, Lackner MR, Sotiriou C, Loi S
Année : 2016
Journal : Ann Oncol
Volume : 27
Pages : 1860-6

The Immunomodulatory Potential of Mesenchymal Stromal Cells: A Story of a Regulatory Network.

Auteurs : Najar M, Raicevic G, Crompot E, Fayyad-Kazan H, Bron D, Toungouz M, Lagneaux L
Année : 2016
Journal : J Immunother
Volume : 39
Pages : 45-59

Prognostic value of CALR vs. JAK2V617F mutations on splenomegaly, leukemic transformation, thrombosis, and overall survival in patients with primary fibrosis: a meta-analysis.

Auteurs : Kourie HR, Ameye L, Paesmans M, Bron D
Année : 2016
Journal : Ann Hematol
Volume : 95(12)
Pages : 2105-2106

Mesenchymal stromal cells and immunomodulation: A gathering of regulatory immune cells.

Auteurs : Najar M, Raicevic G, Fayyad-Kazan H, Bron D, Toungouz M, Lagneaux L
Année : 2016
Journal : Cytotherapy
Volume : 18
Pages : 160-71

Feasibility Study of EndoTAG-1, a Tumor Endothelial Targeting Agent, in Combination with Paclitaxel followed by FEC as Induction Therapy in HER2-Negative Breast Cancer.

Auteurs : Ignatiadis M, Zardavas D, Lemort M, Wilke C, Vanderbeeken MC, Dhondt V, de Azambuja E, Gombos A, Lebrun F, Dal Lago L, Bustin F, Maetens M, Ameye L, Veys I, Michiels S, Paesmans M, Larsimont D, Sotiriou C, Nogaret JM, Piccart-Gebhart M, Awada A
Année : 2016
Journal : PLoS One
Volume : 11(7)
Pages : e0154009

Improved Treatment of Breast Cancer with Anti-HER2 Therapy Requires Interleukin-21 Signaling in CD8+ T Cells.

Auteurs : Mittal D, Caramia F, Michiels S, Joensuu H, Kellokumpu-Lehtinen PL, Sotiriou C, Loi S, Smyth MJ
Année : 2016
Journal : Cancer Res
Volume : 76
Pages : 264-74

Vulnerabilities in Older Patients when Cancer Treatment is Initiated: Does a Cognitive Impairment Impact the Two-Year Survival?

Auteurs : Libert Y, Dubruille S, Borghgraef C, Etienne AM, Merckaert I, Paesmans M, Reynaert C, Roos M, Slachmuylder JL, Vandenbossche S, Bron D, Razavi D
Année : 2016
Journal : PLoS One
Volume : 11
Pages : e0159734

Data on nitric oxide production by human bone marrow-derived mesenchymal stromal cells.

Auteurs : Najar M, Fayyad-Kazan M, Fayyad-Kazan H, Meuleman N, Bron D, Lagneaux L
Année : 2016
Journal : Data Brief
Volume : 8
Pages : 1111-4

Risk-adapted transplant strategies for high-risk Hodgkin lymphoma: are we there?

Auteurs : Lewalle P, Wittnebel S
Année : 2016
Journal : Curr Opin Oncol
Volume : 28
Pages : 390-7

A joint model for the dependence between clustered times to tumour progression and deaths: A meta-analysis of chemotherapy in head and neck cancer.

Auteurs : Rondeau V, Pignon JP, Michiels S
Année : 2015
Journal : Stat Methods Med Res
Volume : 24
Pages : 711-29

Identification of clinical parameters predictive of one-year survival using two geriatric tools in clinically fit older patients with hematological malignancies: Major impact of cognition.

Auteurs : Dubruille S, Libert Y, Roos M, Vandenbossche S, Collard A, Meuleman N, Maerevoet M, Etienne AM, Reynaert C, Razavi D, Bron D
Année : 2015
Journal : J Geriatr Oncol
Volume : 24(3)
Pages : 294-301

Implementation of geriatric assessment-based recommendations in older patients with cancer: A multicentre prospective study.

Auteurs : Baitar A, Kenis C, Moor R, Decoster L, Luce S, Bron D, Van Rijswijk R, Rasschaert M, Langenaeken C, Jerusalem G, Lobelle JP, Flamaing J, Milisen K, Wildiers H
Année : 2015
Journal : J Geriatr Oncol
Volume : 6(5)
Pages : 401-10

Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab: A Secondary Analysis of the NeoALTTO Trial.

Auteurs : Salgado R, Denkert C, Campbell C, Savas P, Nucifero P, Aura C, de Azambuja E, Eidtmann H, Ellis CE, Baselga J, Piccart-Gebhart M, Michiels S, Bradbury I, Sotiriou C, Loi S
Année : 2015
Journal : JAMA Oncol
Volume : 1(4)
Pages : 448-54

Isolation and Characterization of Human Mesenchymal Stromal Cell Subpopulations: Comparison of Bone Marrow and Adipose Tissue.

Auteurs : Busser H, Najar M, Raicevic G, Pieters K, Velez Pombo R, Philippart P, Meuleman N, Bron D, Lagneaux L
Année : 2015
Journal : Stem Cells Dev.
Volume : 24(18)
Pages : 2142-57

Avoiding false positive antigen detection by flow cytometry on blood cell derived microparticles: the importance of an appropriate negative control.

Auteurs : Crompot E, Van Damme M, Duvillier H, Pieters K, Vermeesch M, Perez-Morga D, Meuleman N, Mineur P, Bron D, Lagneaux L, Stamatopoulos B
Année : 2015
Journal : PLoS One
Volume : 10(5)
Pages : e0127209