Genomic aberrations in young and elderly  breast cancer patients.

Auteurs : Azim HA, Nguyen B, Brohée S, Zoppoli G, Sotiriou C
Année : 2015
Journal : BMC Med
Volume : 13
Pages : 266

Integrative proteomic and gene expression analysis identify potential biomarkers for adjuvant trastuzumab resistance: analysis from the Fin-her phase III randomized trial.

Auteurs : Sonnenblick A, Brohée S, Fumagalli D, Rothé F, Vincent D, Ignatiadis M, Desmedt C, Salgado R, Sirtaine N, Loi S, Neven P, Loibl S, Denkert C, Joensuu H, Piccart-Gebhart M, Sotiriou C
Année : 2015
Journal : Oncotarget
Volume : 6
Pages : 30306-16

Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome.

Auteurs : Fumagalli D, Gacquer D, Rothé F, Lefort A, Libert F, Brown D, Kheddoumi N, Shlien A, Konopka T, Salgado R, Larsimont D, Polyak K, Willard-Gallo K, Desmedt C, Piccart-Gebhart M, Abramowicz M, Campbell PJ, Sotiriou C, Detours V
Année : 2015
Journal : Cell Rep
Volume : 13
Pages : 277-89

St Gallen International Expert Consensus on the primary therapy of early breast cancer: an invaluable tool for physicians and scientists.

Auteurs : Ignatiadis M, Buyse M, Sotiriou C
Année : 2015
Journal : Ann Oncol
Volume : 26(8)
Pages : 1519-20

Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity.

Auteurs : Van Keymeulen A, Lee MY, Ousset M, Brohée S, Rorive S, Giraddi RR, Wuidart A, Bouvencourt G, Dubois C, Salmon I, Sotiriou C, Phillips WA, Blanpain C
Année : 2015
Journal : Nature
Volume : 525(7567
Pages : 119-23

CCR 20th Anniversary Commentary: Gene-Expression Signature in Breast Cancer-Where Did It Start and Where Are We Now?

Auteurs : Gingras I, Desmedt C, Ignatiadis M, Sotiriou C
Année : 2015
Journal : Clin Cancer Res
Volume : 21
Pages : 4743-6

Immunology and breast cancer: toward a new way of understanding breast cancer and developing novel therapeutic strategies.

Auteurs : Gingras I, Azim HA Jr, Ignatiadis M, Sotiriou C
Année : 2015
Journal : Clin Adv Hematol Oncol
Volume : 13
Pages : 372-82

Constitutive phosphorylated STAT3-associated gene signature is predictive for trastuzumab resistance in primary HER2-positive breast cancer.

Auteurs : Sonnenblick A, Brohée S, Fumagalli D, Vincent D, Venet D, Ignatiadis M, Salgado R, Van den Eynden G, Rothé F, Desmedt C, Neven P, Loibl S, Denkert C, Joensuu H, Loi S, Sirtaine N, Kellokumpu-Lehtinen PL, Piccart-Gebhart M, Sotiriou C
Année : 2015
Journal : BMC Med
Volume : 13(1)
Pages : 177

Evolving paradigms in multifocal breast cancer.

Auteurs : Salgado R, Aftimos P, Sotiriou C, Desmedt C
Année : 2015
Journal : Semin. Cancer Biol.
Volume : 31C
Pages : 111-118

Subclonal diversification of primary breast cancer revealed by multiregion sequencing.

Auteurs : Yates LR, Gerstung M, Knappskog S, Desmedt C, Gundem G, Van Loo P, Aas T, Alexandrov LB, Larsimont D, Davies H, Li Y, Ju YS, Ramakrishna M, Haugland HK, Lilleng PK, Nik-Zainal S, McLaren S, Butler A, Martin S, Glodzik D, Menzies A, Raine K, Hinton J, Jones D, Mudie LJ, Jiang B, Vincent D, Greene-Colozzi A, Adnet PY, Fatima A, Maetens M, Ignatiadis M, Stratton MR, Sotiriou C, Richardson AL, Lønning PE, Wedge DC, Campbell PJ
Année : 2015
Journal : Nat. Med.
Volume : 21(7)
Pages : 751-9

Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab: A Secondary Analysis of the NeoALTTO Trial.

Auteurs : Salgado R, Denkert C, Campbell C, Savas P, Nucifero P, Aura C, de Azambuja E, Eidtmann H, Ellis CE, Baselga J, Piccart-Gebhart M, Michiels S, Bradbury I, Sotiriou C, Loi S
Année : 2015
Journal : JAMA Oncol
Volume : 1(4)
Pages : 448-54

Uncovering the genomic heterogeneity of multifocal breast cancer.

Auteurs : Desmedt C, Fumagalli D, Pietri E, Zoppoli G, Brown D, Nik-Zainal S, Gundem G, Rothé F, Majjaj S, Garuti A, Carminati E, Loi S, Van Brussel T, Boeckx B, Maetens M, Mudie L, Vincent D, Kheddoumi N, Serra L, Massa I, Ballestrero A, Amadori D, Salgado R, de Wind A, Lambrechts D, Piccart-Gebhart M, Larsimont D, Campbell PJ, Sotiriou C
Année : 2015
Journal : J. Pathol.
Volume : 236(4)
Pages : 457-66

New approaches for improving outcomes in breast cancer in Europe.

Auteurs : Di Leo A, Curigliano G, Diéras V, Malorni L, Sotiriou C, Swanton C, Thompson A, Tutt A, Piccart-Gebhart M
Année : 2015
Journal : Breast
Volume : 24(4)
Pages : 321-330

No significant viral transcription detected in whole breast cancer transcriptomes.

Auteurs : Fimereli D, Gacquer D, Fumagalli D, Salgado R, Rothé F, Larsimont D, Sotiriou C, Detours V
Année : 2015
Journal : BMC Cancer
Volume : 15(null)
Pages : 147

Harmonization of the evaluation of tumor infiltrating lymphocytes (TILs) in breast cancer: recommendations by an international TILs-working group 2014.

Auteurs : Salgado R, Denkert C, Demaria S, Sirtaine N, Klauschen F, Pruneri G, Wienert S, Van den Eynden G, Baehne FL, Penault-Llorca F, Perez EA, Thompson EA, Symmans WF, Richardson AL, Brock J, Criscitiello C, Bailey H, Ignatiadis M, Floris G, Sparano J, Kos Z, Nielsen T, Rimm DL, Allison KH, Reis-Filho JS, Loibl S, Sotiriou C, Viale G, Badve S, Adams S, Willard-Gallo K, Loi S
Année : 2015
Journal : Ann Oncol
Volume : 26(2)
Pages : 259-71

Optimising translational oncology in clinical practice: Strategies to accelerate progress in drug development.

Auteurs : Stahel R, Bogaerts J, Ciardiello F, De Ruysscher D, Dubsky P, Ducreux M, Finn S, Laurent-Puig P, Peters S, Piccart-Gebhart M, Smit E, Sotiriou C, Tejpar S, van Cutsem E, Tabernero J
Année : 2015
Journal : Cancer Treat Rev
Volume : 41(2)
Pages : 129-135

Tumor-Infiltrating Lymphocytes and Response to Neoadjuvant Chemotherapy With or Without Carboplatin in Human Epidermal Growth Factor Receptor 2-Positive and Triple-Negative Primary Breast Cancers.

Auteurs : Denkert C, Von Minckwitz G, Brase JC, Sinn BV, Gade S, Kronenwett R, Pfitzner BM, Salat C, Loi S, Schmitt WD, Schem C, Fisch K, Darb-Esfahani S, Mehta K, Sotiriou C, Wienert S, Klare P, André F, Klauschen F, Blohmer J, Krappmann K, Schmidt M, Tesch H, Kümmel S, Sinn P, Jackisch C, Dietel M, Reimer T, Untch M, Loibl S
Année : 2015
Journal : J. Clin. Oncol.
Volume : 33(9)
Pages : 983-91

Infrared imaging in breast cancer: automated tissue component recognition and spectral characterization of breast cancer cells as well as the tumor microenvironment.

Auteurs : Benard A, Desmedt C, Smolina M, Szternfeld P, Verdonck M, Rouas G, Kheddoumi N, Rothé F, Larsimont D, Sotiriou C, Goormaghtigh E
Année : 2014
Journal : Analyst
Volume : 139(5)
Pages : 1044-56

TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers.

Auteurs : Bottai G, Lehmann-Che J, Kéri G, Orfi L, Iwamoto T, Desmedt C, Bianchini G, Turner NC, de Thè H, André F, Sotiriou C, Hortobagyi GN, Di Leo A, Pusztai L, Santarpia L
Année : 2014
Journal : Mol oncol
Volume : 8(3)
Pages : 508-19

Regulation of DNA Methylation Patterns by CK2-Mediated Phosphorylation of Dnmt3a.

Auteurs : Deplus R, Blanchon L, Rajavelu A, Boukaba A, Defrance M, Luciani J, Rothé F, Dedeurwaerder S, Denis H, Brinkman AB, Simmer F, Müller F, Bertin B, Berdasco M, Putmans P, Calonne E, Litchfield DW, de Launoit Y, Jurkowski TP, Stunnenberg HG, Bock C, Sotiriou C, Fraga MF, Esteller M, Jeltsch A, Fuks F
Année : 2014
Journal : Cell Rep
Volume : 8(3)
Pages : 743-753