Articles scientifiques

Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer.

Auteurs : Hamm A, Prenen H, Van Delm W, Di Matteo M, Wenes M, Delamarre E, Schmidt T, Weitz J, Sarmiento R, Dezi A, Gasparini G, Rothé F, Schmitz R, Dhoore A, Iserentant H, Hendlisz A, Mazzone M
Année : 2016
Journal : Gut
Volume : 65(6)
Pages : 990-1000

Pharmacodynamics, pharmacokinetics and clinical efficacy of neratinib in HER2-positive breast cancer and breast cancer with HER2 mutations.

Auteurs : Kourie HR, Chaix M, Gombos A, Aftimos P, Awada A
Année : 2016
Journal : Expert Opin Drug Metab Toxicol
Volume : 12(8)
Pages : 947-57

Trastuzumab re-treatment following adjuvant trastuzumab and the importance of distant disease-free interval: the HERA trial experience.

Auteurs : Metzger-Filho O, de Azambuja E, Procter M, Krieguer M, Smith I, Baselga J, Cameron D, Untch M, Jackisch C, Bell R, Gianni L, Goldhirsch A, Piccart-Gebhart M, Gelber Rd
Année : 2016
Journal : Breast Cancer Res Treat
Volume : 155
Pages : 127-32

The prognostic performance of Adjuvant! Online and Nottingham Prognostic Index in young breast cancer patients.

Auteurs : Lambertini M, Pinto AC, Ameye L, Jongen L, Del Mastro L, Puglisi F, Poggio F, Bonotto M, Floris G, Van Asten K, Wildiers H, Neven P, de Azambuja E, Paesmans M, Azim HA Jr
Année : 2016
Journal : Br J Cancer
Volume : 115(12)
Pages : 1471-78

A European Organisation for Research and Treatment of Cancer randomized, double-blind, placebo-controlled, multicentre phase II trial of anastrozole in combination with gefitinib or placebo in hormone receptor-positive advanced breast cancer (NCT0006

Auteurs : Tryfonidis K, Basaran G, Bogaerts J, Debled M, Dirix L, Thery JC, Tjan-Heijnen VC, Van den Weyngaert D, Cufer T, Piccart-Gebhart M, Cameron D
Année : 2016
Journal : Eur J Cancer
Volume : 53
Pages : 144-54

Molecular imaging as a tool to investigate heterogeneity of advanced HER2-positive breast cancer and to predict patient outcome under trastuzumab emtansine (T-DM1): the ZEPHIR Trial.

Auteurs : Gebhart G, Lamberts LE, Wimana Z, Garcia C, Emonts P, Ameye L, Stroobants S, Huizing M, Aftimos P, Tol J, Oyen WJ, Vugts DJ, Hoekstra OS, Schröder CP, Menke-van der Houven van Oordt CW, Guiot T, Brouwers AH, Awada A, de Vries EG, Flamen P
Année : 2016
Journal : Ann Oncol
Volume : 27(4)
Pages : 619-24

Checkpoint inhibitors: outstanding efficacy but at what cost?

Auteurs : Klastersky J
Année : 2016
Journal : Curr Opin Oncol
Volume : 28
Pages : 253

Targeted adjuvant therapy in breast cancer.

Auteurs : Zardavas D, Tryfonidis K, Goulioti T, Piccart-Gebhart M
Année : 2016
Journal : Expert Rev Anticancer Ther
Volume : 16(12)
Pages : 1263-75

Why balls are not put inside the basket? A reflection on testicular cancer clinical trial design.

Auteurs : Kourie HR, Aoun F
Année : 2016
Journal : Invest New Drugs
Volume : 34(4)
Pages : 513-4

Will Testicular Germ Cell Tumors Remain Untargetable?

Auteurs : Aoun F, Kourie HR, Albisinni S, Roumeguère T
Année : 2016
Journal : Target Oncol
Volume : 11(6)
Pages : 711-21

Menopausal hormone therapy use in relation to breast cancer incidence in 11 European countries.

Auteurs : Antoine C, Ameye L, Paesmans M, de Azambuja E, Rozenberg S
Année : 2016
Journal : Maturitas
Volume : 84
Pages : 81-8

Salvage esophagectomy after failure of definitive radiochemotherapy for esophageal cancer.

Auteurs : Farinella E, Safar A, Nasser HA, Bouazza F, Liberale G, Paesmans M, Marechal R, Van Laethem JL, Hendlisz A, VanHoutte P, El Nakadi I
Année : 2016
Journal : J Surg Oncol
Volume : 114
Pages : 833-837

Breast cancer in 2015: Academic research sheds light on issues that matter to patients.

Auteurs : Piccart-Gebhart M, Gingras I
Année : 2016
Journal : Nat Rev Clin Oncol
Volume : 13
Pages : 67-8

Phase 2 Study of Trabectedin in Patients With Hormone Receptor-Positive, HER-2-Negative, Advanced Breast Carcinoma According to Expression of Xeroderma Pigmentosum G Gene.

Auteurs : Awada A, Cortés J, Martín M, Aftimos P, Oliveira M, López-Tarruella S, Espie M, Lardelli P, Extremera S, Fernández-García EM, Delaloge S
Année : 2016
Journal : Clin Breast Cancer
Volume : 16(5)
Pages : 364-71

Clinical relevance of host immunity in breast cancer: from TILs to the clinic.

Auteurs : Savas P, Salgado R, Denkert C, Sotiriou C, Darcy PK, Smyth MJ, Loi S
Année : 2016
Journal : Nat Rev Clin Oncol
Volume : 13(4)
Pages : 228-41

Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer.

Auteurs : Bense RD, Sotiriou C, Piccart-Gebhart M, Haanen JB, van Vugt MA, de Vries EG, Schröder CP, Fehrmann RS
Année : 2016
Journal : J Natl Cancer Inst
Volume : 109

Reply to the letter to the editor 'The ESMO Magnitude of Clinical Benefit Scaling Tool: from theory to practice' by Hartmann and the letter 'Comment on ESMO Magnitude of Clinical Benefit Scale' by Muhonen et al.

Auteurs : Cherny NI, Sullivan R, Dafni U, Kerst JM, Sobrero A, Zielinski C, de Vries EG, Piccart-Gebhart M
Année : 2016
Journal : Ann Oncol
Volume : 27
Pages : 203-5

Evaluation of targeted therapies in advanced breast cancer: the need for large-scale molecular screening and transformative clinical trial designs.

Auteurs : Fadoukhair Z, Zardavas D, Chad MA, Goulioti T, Aftimos P, Piccart-Gebhart M
Année : 2016
Journal : Oncogene
Volume : 35(14)
Pages : 1743-9

Soins Intensifs Oncologiques : revue des années 2013 et 2014

Auteurs : Sculier JP, Bucalau AM, Closset J, Compagnie M, Gorham J, Sideris S, Tkint de Roodenbeke D, Wang X, Berghmans T, Meert AP
Année : 2016
Journal : Rev Med Brux
Volume : 37(3
Pages : 159-67

PIK3CA mutations are associated with reduced pathological complete response rates in primary HER2-positive breast cancer: pooled analysis of 967 patients from five prospective trials investigating lapatinib and trastuzumab.

Auteurs : Loibl S, Majewski I, Guarneri V, Nekljudova V, Holmes E, Bria E, Denkert C, Schem C, Sotiriou C, Loi S, Untch M, Conte P, Bernards R, Piccart-Gebhart M, Von Minckwitz G, Baselga J
Année : 2016
Journal : Ann Oncol
Volume : 27(8)
Pages : 1519-25