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 Articles scientifiques

CYAD-01, an autologous NKG2D-based CAR T-cell therapy, in relapsed or refractory acute myeloid leukaemia and myelodysplastic syndromes or multiple myeloma (THINK): haematological cohorts of the dose escalation segment of a phase 1 trial.

Auteurs : Sallman DA, Kerre T, Havelange V, Poiré X, Lewalle P, Wang ES, Brayer JB, Davila ML, Moors I, Machiels JP, Awada A, Alcantar-Orozco EM, Borissova R, Braun N, Dheur MS, Gilham DE, Lonez C, Lehmann FF, Flament A
Année : 2023
Journal : Lancet Haematol

OncomiRs as noncoding RNAs having functions in cancer: Their role in immune suppression and clinical implications.

Auteurs : Otmani K, Rouas R, Lewalle P
Année : 2022
Journal : Front Immunol
Volume : 13
Pages : 913951

Outcomes after allogeneic hematopoietic stem cell transplantation for adults with primary mediastinal B cell lymphoma: a SFGM-TC and LYSA study.

Auteurs : Le Calvez B, Tessoullin B, Renaud L, Botella-Garcia C, Srour M, Le Gouill S, Guillerm G, Gressin R, Nguyen Quoc S, Furst S, Chauchet A, Sibon D, Lewalle P, Poiré X, Maillard N, Villate A, Loschi M, Paillassa J, Beguin Y, Dulery R, Tudesq JJ, Fayard A, Béné MC, Camus V, Chevallier P, Le Bourgeois A
Année : 2022
Journal : Acta Oncol
Volume : 61
Pages : 1332-1338

Sequential administration of low dose 5-azacytidine (AZA) and donor lymphocyte infusion (DLI) for patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) in relapse after allogeneic stem cell transplantation (SCT): a prospective

Auteurs : Poiré X, Graux C, Ory A, Herman J, Baron F, Schoemans H, Lewalle P, De Becker A, Deeren D, Berneman Z, Kerre T, Zachée P, Selleslag D, Beguin Y
Année : 2022
Journal : Bone Marrow Transplant
Volume : 57
Pages : 116-118

New Perspectives in Treating Acute Myeloid Leukemia: Driving towards a Patient-Tailored Strategy.

Auteurs : Andreozzi F, Massaro F, Wittnebel S, Spilleboudt C, Lewalle P, Salaroli A
Année : 2022
Journal : Int J Mol Sci
Volume : 23

Bioscreening and pre-clinical evaluation of the impact of bioactive molecules from Ptychotis verticillata on the multilineage potential of mesenchymal stromal cells towards immune- and inflammation-mediated diseases.

Auteurs : Bouhtit F, Najar M, Rahmani S, Melki R, Najimi M, Sadki K, Boukhatem N, Twizere JC, Meuleman N, Lewalle P, Lagneaux L, Merimi M
Année : 2022
Journal : Inflamm Res
Volume : 71
Pages : 887-898

Use of chimerism analysis after allogeneic stem cell transplantation: Belgian guidelines and review of the current literature.

Auteurs : Delie A, Verlinden A, Beel K, Deeren D, Mazure D, Baron F, Breems D, De Becker A, Graux C, Lewalle P, Maertens J, Poire X, Schoemans H, Selleslag D, Van Obbergh F, Kerre T
Année : 2021
Journal : Acta Clin Belg
Volume : 76(6)
Pages : 500-508

Tumor Suppressor miRNA in Cancer Cells and the Tumor Microenvironment: Mechanism of Deregulation and Clinical Implications.

Auteurs : Otmani K, Lewalle P
Année : 2021
Journal : Front Oncol
Volume : 11
Pages : 708765

Acute Promyelocytic Leukaemia (Apl) In The Elderly Patient.

Auteurs : Salaroli A, Spilleboudt C, Lewalle P, Wittnebel S
Année : 2021
Journal : Belgian J Hematology
Volume : 12(8)
Pages : 332–7

Transcriptional Profile of Cytokines, Regulatory Mediators and TLR in Mesenchymal Stromal Cells after Inflammatory Signaling and Cell-Passaging.

Auteurs : Merimi M, Buyl K, Daassi D, Rodrigues RM, Melki R, Lewalle P, Vanhaecke T, Fahmi H, Rogiers V, Lagneaux L, De Kock J, Najar M
Année : 2021
Journal : Int J Mol Sci
Volume : 22

The Therapeutic Potential of Mesenchymal Stromal Cells for Regenerative Medicine: Current Knowledge and Future Understandings.

Auteurs : Merimi M, El-Majzoub R, Lagneaux L, Moussa Agha D, Bouhtit F, Meuleman N, Fahmi H, Lewalle P, Fayyad-Kazan M, Najar M
Année : 2021
Journal : Front Cell Dev Biol
Volume : 9
Pages : 661532

Therapeutic Mesenchymal Stem/Stromal Cells: Value, Challenges and Optimization.

Auteurs : Najar M, Melki R, Khalife F, Lagneaux L, Bouhtit F, Moussa Agha D, Fahmi H, Lewalle P, Fayyad-Kazan M, Merimi M
Année : 2021
Journal : Front Cell Dev Biol
Volume : 9
Pages : 716853

Apoptotic and Non-Apoptotic Modalities of Thymoquinone-Induced Lymphoma Cell Death: Highlight of the Role of Cytosolic Calcium and Necroptosis.

Auteurs : Berehab M, Rouas R, Akl H, Duvillier H, Journe F, Fayyad-Kazan H, Ghanem G, Bron D, Lewalle P, Merimi M
Année : 2021
Journal : Cancers (Basel)
Volume : 13

Mesenchymal Stem/Stromal Cell Therapeutic Features: The Bridge between the Bench and the Clinic.

Auteurs : Merimi M, Lewalle P, Meuleman N, Agha DM, El-Kehdy H, Bouhtit F, Ayoub S, Burny A, Fahmi H, Lagneaux L, Najar M
Année : 2021
Journal : J Clin Med
Volume : 10

Clinical outcomes in patients with Philadelphia chromosome-positive leukemia treated with ponatinib in routine clinical practice-data from a Belgian registry.

Auteurs : Devos T, Havelange V, Theunissen K, Meers S, Benghiat FS, Gadisseur A, Vanstraelen G, Vellemans H, Bailly B, Granacher N, Lewalle P, De Becker A, Van Eygen K, Janssen M, Triffet A, Vrelust I, Deeren D, Mazure D, Bekaert J, Beck M, Selleslag D
Année : 2021
Journal : Ann Hematol
Volume : 100
Pages : 1723-1732

Immuno-comparative screening of adult-derived human liver stem/progenitor cells for immune-inflammatory-associated molecules.

Auteurs : Merimi M, Lagneaux L, Lombard CA, Agha DM, Bron D, Lewalle P, Meuleman N, Najimi M, Sokal EM, Najar M
Année : 2021
Journal : Inflamm Res
Volume : 70
Pages : 229-239

New Anti-Leukemic Effect of Carvacrol and Thymol Combination through Synergistic Induction of Different Cell Death Pathways.

Auteurs : Bouhtit F, Najar M, Moussa Agha D, Melki R, Najimi M, Sadki K, Boukhatem N, Bron D, Meuleman N, Hamal A, Lagneaux L, Lewalle P, Merimi M
Année : 2021
Journal : Molecules
Volume : 26

Donor-Derived Myeloid Heme Oxygenase-1 Controls the Development of Graft-Versus-Host Disease.

Auteurs : Spilleboudt C, de Wilde V, Lewalle P, Cabanne L, Leclerc M, Beckerich F, Bories D, Cardoso S, Soares MP, Vokaer B, Hougardy JM, Flamand V, Racapé J, Abramowicz M, Maury S, Le Moine A
Année : 2021
Journal : Front Immunol
Volume : 11
Pages : 579151

Clinical applications of donor lymphocyte infusion from an HLA-haploidentical donor: consensus recommendations from the Acute Leukemia Working Party of the EBMT.

Auteurs : Dholaria B, Savani BN, Labopin M, Luznik L, Ruggeri A, Mielke S, Al Malki MM, Kongtim P, Fuchs E, Huang XJ, Locatelli F, Aversa F, Castagna L, Bacigalupo A, Martelli M, Blaise D, Ben Soussan P, Arnault Y, Handgretinger R, Roy DC, ODonnell P, Bashey A, Solomon S, Romee R, Lewalle P, Gayoso J, Maschan M, Lazarus HM, Ballen K, Giebel S, Baron F, Ciceri F, Esteve J, Gorin NC, Spyridonidis A, Schmid C, Ciurea SO, Nagler A, Mohty M
Année : 2020
Journal : Haematologica
Volume : 105
Pages : 47-58

Mesenchymal Stem/Stromal Cells in Immunity and Disease: A Better Understanding for an Improved Use.

Auteurs : Merimi M, Lagneaux L, Moussa Agha D, Lewalle P, Meuleman N, Burny A, Fahmi H, Najar M
Année : 2020
Journal : J Clin Med
Volume : 9