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 Articles scientifiques

The impact of tumor cell metabolism on T cell-mediated immune responses and immuno-metabolic biomarkers in cancer.

Auteurs : Noël G, Langouo Fontsa M, Willard-Gallo K
Année : 2018
Journal : Semin Cancer Biol
Volume : 52
Pages : 66-74

Immune Infiltration in Invasive Lobular Breast Cancer.

Auteurs : Desmedt C, Salgado R, Fornili M, Pruneri G, Van den Eynden G, Zoppoli G, Rothé F, Buisseret L, Garaud S, Willard-Gallo K, Brown D, Bareche Y, Rouas G, Galant C, Bertucci F, Loi S, Viale G, Di Leo A, Green AR, Ellis IO, Rakha EA, Larsimont D, Biganzoli E, Sotiriou C
Année : 2018
Journal : J Natl Cancer Inst
Volume : 110(7)
Pages : 768-776

The Abscopal Effect in the Era of Cancer Immunotherapy: a Spontaneous Synergism Boosting Anti-tumor Immunity?

Auteurs : Hlavata Z, Solinas C, De Silva P, Porcu M, Saba L, Willard-Gallo K, Scartozzi M
Année : 2018
Journal : Target Oncol
Volume : 13(2)
Pages : 113-123

Immunity drives TET1 regulation in cancer through NF-?B.

Auteurs : Collignon E, Canale A, Al Wardi C, Bizet M, Calonne E, Dedeurwaerder S, Garaud S, Naveaux C, Barham W, Wilson A, Bouchat S, Hubert P, Van Lint C, Yull F, Sotiriou C, Willard-Gallo K, Noel A, Fuks F
Année : 2018
Journal : Sci Adv
Volume : 4
Pages : eaap7309

Radiological evaluation of response to immunotherapy in brain tumors: Where are we now and where are we going?

Auteurs : Porcu M, Solinas C, Garofalo P, de Azambuja E, Scartozzi M, Willard-Gallo K, Preusser M, Saba L
Année : 2018
Journal : Crit Rev Oncol Hematol
Volume : 126
Pages : 135-144

Inflammatory Stroma of Lymphoepithelioma-like Carcinoma of the Cervix: Immunohistochemical Study of 3 Cases and Review of the Literature.

Auteurs : Philippe A, Rassy M, Craciun L, Naveaux C, Willard-Gallo K, Larsimont D, Veys I
Année : 2018
Journal : Int J Gynecol Pathol
Volume : 37
Pages : 482-487

Antigen Specificity and Clinical Significance of IgG and IgA Autoantibodies Produced in situ by Tumor-Infiltrating B Cells in Breast Cancer.

Auteurs : Garaud S, Zayakin P, Buisseret L, Rulle U, Silina K, de Wind A, Van den Eyden G, Larsimont D, Willard-Gallo K
Année : 2018
Journal : Front Immunol
Volume : 9
Pages : 2660

Cancer immunotherapy-associated hypophysitis.

Auteurs : Solinas C, Porcu M, De Silva P, Musi M, Aspeslagh S, Scartozzi M, Willard-Gallo K, Mariotti S, Saba L
Année : 2018
Journal : Semin Oncol
Volume : 45
Pages : 181-186

Quantifying Tertiary Lymphoid Structure-Associated Genes in Formalin-Fixed Paraffin-Embedded Breast Cancer Tissues.

Auteurs : Gu-Trantien C, Garaud S, Migliori E, Solinas C, Lodewyckx JN, Willard-Gallo K
Année : 2018
Journal : Methods Mol Biol
Volume : 1845
Pages : 139-157

Critical features and challenges associated with imaging in patients undergoing cancer immunotherapy.

Auteurs : Solinas C, Porcu M, Hlavata Z, De Silva P, Puzzoni M, Willard-Gallo K, Scartozzi M, Saba L
Année : 2017
Journal : Crit Rev Oncol Hematol
Volume : 120
Pages : 13-21

Immune Checkpoint Molecules on Tumor-Infiltrating Lymphocytes and Their Association with Tertiary Lymphoid Structures in Human Breast Cancer.

Auteurs : Solinas C, Garaud S, De Silva P, Boisson A, Van den Eynden G, de Wind A, Risso P, Rodrigues Vitória J, Richard F, Migliori E, Noël G, Duvillier H, Craciun L, Veys I, Awada A, Detours V, Larsimont D, Piccart-Gebhart M, Willard-Gallo K
Année : 2017
Journal : Front Immunol
Volume : 8
Pages : 1412

PD-1 hi CXCR5- CD4 + T FH Cells Play Defense in Cancer and Offense in Arthritis.

Auteurs : Gu-Trantien C, Willard-Gallo K
Année : 2017
Journal : Trends Immunol
Volume : 38(12)
Pages : 875-878

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Car

Auteurs : Hendry S, Salgado R, Gevaert T, Russell PA, John T, Thapa B, Christie M, Van de Vijver K, Estrada MV, Gonzalez-Ericsson PI, Sanders M, Solomon B, Solinas C, Van den Eynden GGGM, Allory Y, Preusser M, Hainfellner J, Pruneri G, Vingiani A, Demaria S, Symmans F, Nuciforo P, Comerma L, Thompson EA, Lakhani S, Kim SR, Schnitt S, Colpaert C, Sotiriou C, Scherer SJ, Ignatiadis M, Badve S, Pierce RH, Viale G, Sirtaine N, Penault-Llorca F, Sugie T, Fineberg S, Paik S, Srinivasan A, Richardson A, Wang Y, Chmielik E, Brock J, Johnson DB, Balko J, Wienert S, Bossuyt V, Michiels S, Ternes N, Burchardi N, Luen SJ, Savas P, Klauschen F, Watson PH, Nelson BH, Criscitiello C, OToole S, Larsimont D, de Wind R, Curigliano G, André F, Lacroix-Triki M, van de Vijver M, Rojo F, Floris G, Bedri S, Sparano J, Rimm D, Nielsen T, Kos Z, Hewitt S, Singh B, Farshid G, Loibl S, Allison KH, Tung N, Adams S, Willard-Gallo K, Horlings HM, Gandhi L, Moreira A, Hirsch F, Dieci MV, Urbanowicz M, Brcic I, Korski K, Gaire F, Koeppen H, Lo A, Giltnane J, Rebelatto MC, Steele KE, Zha J, Emancipator K, Juco JW, Denkert C, Reis-Filho J, Loi S, Fox SB
Année : 2017
Journal : Adv Anat Pathol
Volume : 24
Pages : 311-335

FOXP1 is a key regulator of quiescence in healthy human CD3+ CD4+ T Cells and is constitutively repressed in CD3- CD4+ T cells from patients with lymphoproliferative disorders.

Auteurs : Garaud S, Roufosse F, De Silva P, Gu-Trantien C, Lodewyckx JN, Duvillier H, Dedeurwaerder S, Bizet M, Defrance M, Fuks F, Bex F, Willard-Gallo K
Année : 2017
Journal : Eur J Immunol
Volume : 47(1)
Pages : 168-179

CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer.

Auteurs : Gu-Trantien C, Migliori E, Buisseret L, de Wind A, Brohée S, Garaud S, Noël G, Dang Chi VL, Lodewyckx JN, Naveaux C, Duvillier H, Goriely S, Larsimont D, Willard-Gallo K
Année : 2017
Journal : JCI Insight
Volume : 2

Tumor-infiltrating lymphocytes in patients with HER2-positive breast cancer treated with neoadjuvant chemotherapy plus trastuzumab, lapatinib or their combination: A meta-analysis of randomized controlled trials.

Auteurs : Solinas C, Ceppi M, Lambertini M, Scartozzi M, Buisseret L, Garaud S, Fumagalli D, de Azambuja E, Salgado R, Sotiriou C, Willard-Gallo K, Ignatiadis M
Année : 2017
Journal : Cancer Treat Rev
Volume : 57
Pages : 8-15

Reliability of tumor-infiltrating lymphocyte and tertiary lymphoid structure assessment in human breast cancer.

Auteurs : Buisseret L, Desmedt C, Garaud S, Fornili M, Wang X, Van den Eyden G, de Wind A, Duquenne S, Boisson A, Naveaux C, Rothé F, Rorive S, Decaestecker C, Larsimont D, Piccart-Gebhart M, Biganzoli E, Sotiriou C, Willard-Gallo K
Année : 2017
Journal : Mod Pathol
Volume : 30(9)
Pages : 1204-1212

Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in I

Auteurs : Hendry S, Salgado R, Gevaert T, Russell PA, John T, Thapa B, Christie M, Van de Vijver K, Estrada MV, Gonzalez-Ericsson PI, Sanders M, Solomon B, Solinas C, Van den Eynden GGGM, Allory Y, Preusser M, Hainfellner J, Pruneri G, Vingiani A, Demaria S, Symmans F, Nuciforo P, Comerma L, Thompson EA, Lakhani S, Kim SR, Schnitt S, Colpaert C, Sotiriou C, Scherer SJ, Ignatiadis M, Badve S, Pierce RH, Viale G, Sirtaine N, Penault-Llorca F, Sugie T, Fineberg S, Paik S, Srinivasan A, Richardson A, Wang Y, Chmielik E, Brock J, Johnson DB, Balko J, Wienert S, Bossuyt V, Michiels S, Ternes N, Burchardi N, Luen SJ, Savas P, Klauschen F, Watson PH, Nelson BH, Criscitiello C, OToole S, Larsimont D, de Wind R, Curigliano G, André F, Lacroix-Triki M, van de Vijver M, Rojo F, Floris G, Bedri S, Sparano J, Rimm D, Nielsen T, Kos Z, Hewitt S, Singh B, Farshid G, Loibl S, Allison KH, Tung N, Adams S, Willard-Gallo K, Horlings HM, Gandhi L, Moreira A, Hirsch F, Dieci MV, Urbanowicz M, Brcic I, Korski K, Gaire F, Koeppen H, Lo A, Giltnane J, Rebelatto MC, Steele KE, Zha J, Emancipator K, Juco JW, Denkert C, Reis-Filho J, Loi S, Fox SB
Année : 2017
Journal : Adv Anat Pathol
Volume : 24
Pages : 235-251

DNA methylation-based immune response signature improves patient diagnosis in multiple cancers.

Auteurs : Jeschke J, Bizet M, Desmedt C, Calonne E, Dedeurwaerder S, Garaud S, Koch A, Larsimont D, Salgado R, Van den Eynden G, Willard-Gallo K, Bontempi G, Defrance M, Sotiriou C, Fuks F
Année : 2017
Journal : J Clin Invest
Volume : 127(8)
Pages : 3090-3102

Immunology of Solid Tumors Beyond Tumor-Infiltrating Lymphocytes: The Role of Tertiary Lymphoid Structures

Auteurs : Van den Eyden G, Salgado R, Willard-Gallo K
Année : 2017
Journal : Springer nature
Volume : -
Pages : 259-280