High stromal Foxp3-positive T cell number combined to tumor stage improved prognosis in head and neck squamous cell carcinoma.

Authors : Kindt N, Descamps G, Seminerio I, Bellier J, Lechien JR, Mat Q, Pottier C, Delvenne P, Journe F, Saussez S
Year : 2017
Journal : Oral Oncol
Volume : 67
Pages : 183-191

Role of macrophage migration inhibitory factor in head and neck cancer and novel therapeutic targets: A systematic review.

Authors : Lechien JR, Nassri A, Kindt N, Brown DN, Journe F, Saussez S
Year : 2017
Journal : Head Neck
Volume : 39(12)
Pages : 2573-2584

P53 and MITF/Bcl-2 identified as key pathways in the acquired resistance of NRAS-mutant melanoma to MEK inhibition.

Authors : Najem A, Krayem M, Sales F, Hussein N, Badran B, Robert C, Awada A, Journe F, Ghanem G
Year : 2017
Journal : Eur J Cancer
Volume : 83
Pages : 154-165

Breast cancer cells and bone marrow mesenchymal stromal cells: a regulated modulation of the breast tumor in the context of immune response.

Authors : Najar M, Fayyad-Kazan H, Faour WH, Badran B, Journe F, Lagneaux L
Year : 2017
Journal : Inflamm Res
Volume : 66(2)
Pages : 129-39

Langerhans cell number is a strong and independent prognostic factor for head and neck squamous cell carcinomas.

Authors : Kindt N, Descamps G, Seminerio I, Bellier J, Lechien JR, Pottier C, Larsimont D, Journe F, Delvenne P, Saussez S
Year : 2016
Journal : Oral Oncol
Volume : 62
Pages : 1-10

Classical risk factors, but not HPV status, predict survival after chemoradiotherapy in advanced head and neck cancer patients.

Authors : Descamps G, Karaca Y, R Lechien J, Kindt N, Decaestecker C, Remmelink M, Larsimont D, Andry G, Hassid S, Rodriguez A, Khalife M, Journe F, Saussez S
Year : 2016
Journal : J Cancer Res Clin Oncol
Volume : 142(10)
Pages : 2185-96

The impact of adjuvant chemotherapy in older breast cancer patients on clinical and biological aging parameters.

Authors : Brouwers B, Hatse S, Dal Lago L, Neven P, Vuylsteke P, Dalmasso B, Debrock G, Van den Bulck H, Smeets A, Bechter O, Kini Bailur J, Kenis C, Laenen A, Schöffski P, Pawelec G, Journe F, Ghanem G, Wildiers H
Year : 2016
Journal : Oncotarget
Volume : 7(21)
Pages : 29977-88

p53 Reactivation by PRIMA-1 Met (APR-246) sensitises V600E/K BRAF melanoma to vemurafenib.

Authors : Krayem M, Journe F, Wiedig M, Morandini R, Najem A, Sales F, Van Kempen LC, Sibille C, Awada A, Marine JC, Ghanem G
Year : 2016
Journal : Eur J Cancer
Volume : 55
Pages : 98-110

SNPs at miR-155 binding sites of TYRP1 explain discrepancy between mRNA and protein and refine TYRP1 prognostic value in melanoma.

Authors : El Hajj P, Gilot D, Migault M, Theunis A, Van Kempen LC, Sales F, Fayyad-Kazan H, Badran B, Larsimont D, Awada A, Bachelot L, Galibert MD, Ghanem G, Journe F
Year : 2015
Journal : Br J Cancer
Volume : 113(1)
Pages : 91-8

Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state.

Authors : Verfaillie A, Imrichova H, Atak ZK, Dewaele M, Rambow F, Hulselmans G, Christiaens V, Svetlichnyy D, Luciani F, Van den Mooter L, Claerhout S, Fiers M, Journe F, Ghanem G, Herrmann C, Halder G, Marine JC, Aerts S
Year : 2015
Journal : Nat Commun
Volume : 6(null)
Pages : 6683

Prominent role of cyclic adenosine monophosphate signalling pathway in the sensitivity of (WT)BRAF/(WT)NRAS melanoma cells to vemurafenib.

Authors : Krayem M, Journe F, Wiedig M, Morandini R, Sales F, Awada A, Ghanem G
Year : 2014
Journal : Eur. J. Cancer
Volume : 50(7)
Pages : 1310-20

HER4 and its cytoplasmic isoforms are associated with progression-free survival of malignant melanoma.

Authors : Nielsen TO, Poulsen SS, Journe F, Ghanem G, Sorensen BS
Year : 2014
Journal : Melanoma Res.
Volume : 24(1)
Pages : 88-91

Sequential use of protein kinase inhibitors potentiates their toxicity to melanoma cells: A rationale to combine targeted drugs based on protein expression inhibition profiles.

Authors : Aftimos P, Wiedig M, Langouo Fontsa M, Awada A, Ghanem G, Journe F
Year : 2013
Journal : Int J Oncol
Volume : 43(3)
Pages : 919-26

Pharmacological inhibition of macrophage migration inhibitory factor interferes with the proliferation and invasiveness of squamous carcinoma cells.

Authors : Kindt N, Laurent G, Nonclercq D, Journe F, Ghanem G, Duvillier H, Gabius HJ, Lechien J, Saussez S
Year : 2013
Journal : Int J Oncol
Volume : 43(1)
Pages : 185-93

Tyrosinase-related protein 1 mRNA expression in lymph node metastases predicts overall survival in high-risk melanoma patients.

Authors : El Hajj P, Journe F, Wiedig M, Laios I, Sales F, Galibert MD, Van Kempen LC, Spatz A, Badran B, Larsimont D, Awada A, Ghanem G
Year : 2013
Journal : Br J Cancer
Volume : 108(8)
Pages : 1641-7

Functional status and relationships of melanocortin 1 receptor signaling to the cAMP and extracellular signal-regulated protein kinases 1 and 2 pathways in human melanoma cells.

Authors : Herraiz C, Journe F, Ghanem G, Jiménez-Cervantes C, García-Borrón JC
Year : 2012
Journal : Int. J. Biochem. Cell Biol.
Volume : 44(12)
Pages : 2244-2252

Characterization and clinical evaluation of CD10+ stroma cells in the breast cancer microenvironment.

Authors : Desmedt C, Majjaj S, Kheddoumi N, Singhal SK, Haibe-Kains B, El Ouriaghli F, Chaboteaux C, Michiels S, Lallemand F, Journe F, Duvillier H, Loi S, Quackenbush J, Dekoninck S, Blanpain C, Lagneaux L, Houhou N, Delorenzi M, Larsimont D, Piccart-Gebhart M, Sotiriou C
Year : 2012
Journal : Clin Cancer Res
Volume : 18(4)
Pages : 1004-14

TYRP1 mRNA expression in melanoma metastases correlates with clinical outcome.

Authors : Journe F, Id Boufker H, Van Kempen L, Galibert MD, Wiedig M, Sales F, Theunis A, Nonclercq D, Frau A, Laurent G, Awada A, Ghanem G
Year : 2011
Journal : Br J Cancer
Volume : 105(11)
Pages : 1726-32

Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.

Authors : Herraiz C, Journe F, Abdel-Malek Z, Ghanem G, Jiménez-Cervantes C, García-Borrón JC
Year : 2011
Journal : Mol. Endocrinol.
Volume : 25(1)
Pages : 138-56

Role of farnesoid X receptor (FXR) in the process of differentiation of bone marrow stromal cells into osteoblasts.

Authors : Id Boufker H, Lagneaux L, Fayyad-Kazan H, Badran B, Najar M, Wiedig M, Ghanem G, Laurent G, Body JJ, Journe F
Year : 2011
Journal : Bone
Volume : 49(6)
Pages : 1219-31