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 Scientific publications

Tumor biology reflected by histological growth pattern is more important than surgical margin for the prognosis of patients undergoing resection of colorectal liver metastases.

Authors : Bohlok A, Inchiostro L, Lucidi V, Vankerckhove S, Hendlisz A, Van Laethem JL, Craciun L, Demetter P, Larsimont D, Dirix L, Vermeulen P, Donckier V
Year : 2023
Journal : Eur J Surg Oncol
Volume : 49
Pages : 217-224

Ferroptosis Induction and YAP Inhibition as New Therapeutic Targets in Gastrointestinal Stromal Tumors (GISTs).

Authors : Delvaux M, Hagué P, Craciun L, Wozniak A, Demetter P, Schöffski P, Erneux C, Vanderwinden JM
Year : 2022
Journal : Cancers (Basel)
Volume : 14

Thyroid cancer under the scope of emerging technologies.

Authors : Tarabichi M, Demetter P, Craciun L, Maenhaut C, Detours V
Year : 2022
Journal : Mol Cell Endocrinol
Volume : 541
Pages : 111491

The Use of Pan-Tropomyosin Receptor Kinase Immunohistochemistry as a Screening Tool for the Detection of Neurotrophic Tropomyosin-Related Kinase Fusions: Real-World Data from a National Multicentric Retrospective Study.

Authors : Van Bockstal MR, Beniuga G, Craciun L, Creytens D, Dedeurwaerdere F, Delvenne P, Demetter P, De Wiest B, Dewinne K, Habran L, Pauwels P, Theate I, Vander Borght S, Van Der Steen K, Weynand B
Year : 2022
Journal : Pathobiology
Pages : 1-14

Transcriptional output, cell-type densities, and normalization in spatial transcriptomics.

Authors : Saiselet M, Rodrigues-Vitória J, Tourneur A, Craciun L, Spinette A, Larsimont D, Andry G, Lundeberg J, Maenhaut C, Detours V
Year : 2021
Journal : J Mol Cell Biol
Volume : 12
Pages : 906-908

Functional Th1-oriented T follicular helper cells that infiltrate human breast cancer promote effective adaptive immunity.

Authors : Noël G, Fontsa ML, Garaud S, De Silva P, de Wind A, Van den Eynden GG, Salgado R, Boisson A, Locy H, Thomas N, Solinas C, Migliori E, Naveaux C, Duvillier H, Lucas S, Craciun L, Thielemans K, Larsimont D, Willard-Gallo K
Year : 2021
Journal : J Clin Invest
Volume : 131

Neo-CheckRay: radiation therapy and adenosine pathway blockade to increase benefit of immuno-chemotherapy in early stage luminal B breast cancer, a randomized phase II trial.

Authors : De Caluwe A, Buisseret L, Poortmans P, Van Gestel D, Salgado R, Sotiriou C, Larsimont D, Paesmans M, Craciun L, Drisis S, Vandekerckhove C, Reyal F, Veys I, Eiger D, Piccart-Gebhart M, Romano E, Ignatiadis M
Year : 2021
Journal : BMC Cancer
Volume : 21
Pages : 899

Fluorescent Multiplex Immunohistochemistry Coupled With Other State-Of-The-Art Techniques to Systematically Characterize the Tumor Immune Microenvironment.

Authors : Boisson A, Noël G, Saiselet M, Rodrigues-Vitória J, Thomas N, Fontsa ML, Sofronii D, Naveaux C, Duvillier H, Craciun L, Larsimont D, Awada A, Detours V, Willard-Gallo K, Garaud S
Year : 2021
Journal : Front Mol Biosci
Volume : 8
Pages : 673042

Feasibility and clinical impact of routine molecular testing of gastrointestinal cancers at a tertiary centre with a multi-gene, tumor-agnostic, next generation sequencing panel.

Authors : Bregni G, Sticca T, Camera S, Akin Telli T, Craciun L, Trevisi E, Pretta A, Kehagias P, Leduc S, Senti C, Deleporte A, Vandeputte C, Saad ED, Kerger J, Gil T, Piccart-Gebhart M, Awada A, Demetter P, Larsimont D, Hendlisz A, Aftimos P, Sclafani F
Year : 2020
Journal : Acta oncol (Stockholm)
Volume : 59
Pages : 1438-1446

Infiltrative tumour growth pattern correlates with poor outcome in oesophageal cancer.

Authors : Anciaux M, Demetter P, de Wind R, Gomez Galdon M, Vande Velde S, Lens G, Craciun L, Deleruelle A, Larsimont D, Lenaerts T, Sclafani F, Deleporte A, Donckier V, Hendlisz A, Vandeputte C
Year : 2020
Journal : BMJ Open Gastroenterol
Volume : 7

Retrospective analysis of the immunogenic effects of intra-arterial locoregional therapies in hepatocellular carcinoma: a rationale for combining selective internal radiation therapy (SIRT) and immunotherapy.

Authors : Craciun L, de Wind R, Demetter P, Willard-Gallo K, Lucidi V, Bohlok A, Michiels S, Bouazza F, Vouche M, Tancredi I, Verset G, Garaud S, Naveaux C, Gomez Galdon M, Hendlisz A, Derijckere ID, Flamen P, Larsimont D, Donckier V
Year : 2020
Journal : BMC Cancer
Volume : 20
Pages : 135

Tumor Banks: A Quality Control Scheme Proposal.

Authors : Craciun L, Spinette SA, Rassy M, Salgado R, de Wind A, Demetter P, Verset L, Gomez Galdon M, Chintinne M, Sirtaine N, de St Aubain N, Laios I, Roy F, Larsimont D
Year : 2019
Journal : Front Med (Lausanne)
Volume : 6
Pages : 225

Tumor infiltrating B-cells signal functional humoral immune responses in breast cancer.

Authors : Garaud S, Buisseret L, Solinas C, Gu-Trantien C, de Wind A, Van den Eynden G, Naveaux C, Lodewyckx JN, Boisson A, Duvillier H, Craciun L, Ameye L, Veys I, Paesmans M, Larsimont D, Piccart-Gebhart M, Willard-Gallo K
Year : 2019
Journal : JCI Insight
Volume : 5

FOXP1 negatively regulates tumor infiltrating lymphocyte migration in human breast cancer.

Authors : De Silva P, Garaud S, Solinas C, de Wind A, Van den Eyden G, Jose V, Gu-Trantien C, Migliori E, Boisson A, Naveaux C, Duvillier H, Craciun L, Larsimont D, Piccart-Gebhart M, Willard-Gallo K
Year : 2019
Journal : EBioMedicine
Volume : 39
Pages : 226-238

Reprogramming of Energy Metabolism: Increased Expression and Roles of Pyruvate Carboxylase in Papillary Thyroid Cancer.

Authors : Strickaert A, Corbet C, Spinette SA, Craciun L, Dom G, Andry G, Larsimont D, Wattiez R, Dumont JE, Feron O, Maenhaut C
Year : 2019
Journal : Thyroid
Volume : 29
Pages : 845-857

BRCA gene mutations do not shape the extent and organization of tumor infiltrating lymphocytes in triple negative breast cancer.

Authors : Solinas C, Marcoux D, Garaud S, Vitória JR, Van den Eynden G, de Wind A, De Silva P, Boisson A, Craciun L, Larsimont D, Piccart-Gebhart M, Detours V, Tkint de Roodenbeke D, Willard-Gallo K
Year : 2019
Journal : Cancer Lett
Volume : 450
Pages : 88-97

Thyroid follicular adenomas and carcinomas: molecular profiling provides evidence for a continuous evolution.

Authors : Dom G, Frank S, Floor S, Kehagias P, Libert F, Hoang C, Andry G, Spinette A, Craciun L, de Saint-Aubain de Somerhausen N, Tresallet C, Tissier F, Savagner F, Majjaj S, Gutierrez-Roelens I, Marbaix E, Dumont JE, Maenhaut C
Year : 2018
Journal : Oncotarget
Volume : 9
Pages : 10343-10359

Inflammatory Stroma of Lymphoepithelioma-like Carcinoma of the Cervix: Immunohistochemical Study of 3 Cases and Review of the Literature.

Authors : Philippe A, Rassy M, Craciun L, Naveaux C, Willard-Gallo K, Larsimont D, Veys I
Year : 2018
Journal : Int J Gynecol Pathol
Volume : 37
Pages : 482-487

Distinctive desmoplastic 3D morphology associated with BRAFV600E in papillary thyroid cancers.

Authors : Tarabichi M, Antoniou A, Le Pennec S, Gacquer D, de Saint-Aubain de Somerhausen N, Craciun L, Cielen T, Laios I, Larsimont D, Andry G, Dumont JE, Maenhaut C, Detours V
Year : 2018
Journal : J Clin Endocrinol Metab
Volume : 103(3)
Pages : 1102-1111

Immune Checkpoint Molecules on Tumor-Infiltrating Lymphocytes and Their Association with Tertiary Lymphoid Structures in Human Breast Cancer.

Authors : Solinas C, Garaud S, De Silva P, Boisson A, Van den Eynden G, de Wind A, Risso P, Rodrigues Vitória J, Richard F, Migliori E, Noël G, Duvillier H, Craciun L, Veys I, Awada A, Detours V, Larsimont D, Piccart-Gebhart M, Willard-Gallo K
Year : 2017
Journal : Front Immunol
Volume : 8
Pages : 1412