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Statut de l'essai
Trial Phase
Type d'essai
336 clinical trials grid list download
Body (indexed field) Identifiant (ID) Email
22672 >=65 years old or, 18 to 64 years old and have at least 1 of the following: 1) CIRS score >6 or
2) Creatinine clearance estimated <70 mL/min - At least one lymph node >1.5 cm by CT - Absence of del 17p or TP53 mutation
Dominique Bron LLC Janssen GLOW Trial closed for recruitment Randomized, Open-label, Phase 3 study of the Combination of Ibrutinib plus Venetoclax versus Chlorambucil plus Obinutuzumab for the First-line Treatment of Subjects with Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) dominique.bron@hubruxelles.be 3 3
22666 RECIST v1.1 Ahmad Hussein Awada Multiple Genoscience Pharma GNS561-CL-I-Q-0211 Trial closed for recruitment New Title: Phase 1/2a study to evaluate the safety, activity, and pharmacokinetics of escalating doses of GNS561 in patients with primary or secondary liver cancer.
(Old Title: Phase 1/2a study to evaluate the safety, activity, and pharmacokinetics of escalating doses of GNS561 in patients with primary liver cancer)
ahmad.awada@hubruxelles.be 1 1
22816 HER 2-/HR+ Ahmad Hussein Awada Breast Genentech GO 28509 Trial closed GO 28509 A phase II, randomized study of paclitaxel with GDC-0941 versus paclitaxel with placebo in patients with locally recurrent or metastatic breast cancer ahmad.awada@hubruxelles.be 2 2
22764 any line Ahmad Hussein Awada Multiple Genentech-Roche GO29674 Trial closed A Phase Ib, Open-Label, Dose-escalation Study of the safety and Pharmacokinetics of MOXR0916 and MPDL3280A in Patients with Locally Advanced or Metastatic Solid Tumors ahmad.awada@hubruxelles.be 1 1
28490 Thierry Berghmans Lung Roche GO41892 - (CONTACT-01) Trial closed for recruitment A phase III, multicenter, randomized, open-label, controlled study to evaluate the efficacy, safety, and pharmacokinetics of tezolizumab given in combination with cabozantinib versus docetaxel monotherapy in patients with metastatic non-small cell lung cancer previously treated with an anti-PD-L1/PD-1 antibody and platinum-containing chemotherapy 3 3
29413 blood and bone marrow exploration mandatory before steroids prephase /ALL B Phi negative, ALL B Phi positive, and ALL T eligible Sebastian Wittnebel Acute leukemia APHP GRAALL-2014 trial Trial closed Multicenter trial for the treatment of Acute Lymhoblastic Leukemia (ALL) in younger adults (18-59 years) (GRAALL-2014 trial) Sebastian.Wittnebel@hubruxelles.be 2/3 2
28537 Triple negative Ahmad Hussein Awada Breast Erytech GRASPA-TNBC-2018-02 Trial closed A Randomized Phase 2/3 Study of Eryaspase in Combination with Gemcitabine and Carboplatin Chemotherapy versus Chemotherapy Alone As First-Line Treatment in Patients with Metastatic or Locally Recurrent Triple-Negative Breast Cancer ahmad.awada@hubruxelles.be 2/3 2
28624 1. moderate or severe cGVHD per NIH Consensus Criteria
2. KPS score > 60%.
3. Evidence of myeloid and platelet engraftment, that is, ANC > 1.0 × 10e9/L and platelet
count > 50 × 10e9/L.
4. Has not received more than 3 days/72 hours of systemic corticoster
Sebastian Wittnebel NA Incyte Corporate GRAVITAS-309 Trial closed A Phase 2/3 Study of Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease (GRAVITAS-309) Sebastian.Wittnebel@hubruxelles.be 2/3 2
22646 no suitable HLA-matched sibling or unrelated donor / no prior allogeneic stem cell transplantation/ AML, ALL or MDS Philippe Lewalle Multiple Kiadis Pharma HATCY study Trial closed A Phase III, multicenter, randomized controlled study to compare safety and efficacy of a haploidentical HSCT and adjunctive treatment with ATIR101, a T-lymphocyte enriched leukocyte preparation depleted ex vivo of host alloreactive T-cells, versus a haploidentical HSCT with post-transplant cyclophosphamide in patients with a hematologic malignancy philippe.lewalle@hubruxelles.be 3 3
28578 Andrea Gombos Breast Seagen HER2CLIMB-02 Trial closed for recruitment Randomized, double-blind, Phase III Trial of tucatinib or Placebo in combination with ado-trastuzumab emtansine (T-DM1) for subjects with unresectable locally-advanced or metastatic HER2+ breast cancer (HER2CLIMB-02) accueil.oncologie@hubruxelles.be 3 3
28584 IDH1 or IDH2 +, fit for standard chemotherapy Sebastian Wittnebel Acute leukemia Hovon HOVON 150 AML/ AMLSG 29-18 Trial open for recruitment A phase 3, multicenter, double-blind, randomized, placebo-controlled study of ivosidenib or enasidenib in combination with induction therapy and consolidation therapy followed by maintenance therapy in patients with newly diagnosed acute myeloid leukemia or myelodysplastic syndrome with excess blasts-2, with an IDH1 or IDH2 mutation, respectively, eligible for intensive chemotherapy (HOVON 150 AML/ AMLSG 29-18) Sebastian.Wittnebel@hubruxelles.be 3 3
29135 Presence of the FLT3 mutation Adriano Salaroli Acute leukemia Hovon HOVON 156 AML / AMLSG 28-18 Trial closed for recruitment A phase 3, multicenter, open-label, randomized, study of gilteritinib versus midostaurin in combination with induction and consolidation therapy followed by one-year maintenance in patients with newly diagnosed Acute Myeloid Leukemia (AML) or Myelodysplastic syndromes with excess blasts-2 (MDS-EB2) with FLT3 mutations eligible for intensive chemotherapy adriano.salaroli@hubruxelles.be 3 3
29290 Angela Loizidou Bordet I-SPARC Trial closed Immune response in patients with cancer undergoing vaccination against SARS-CoV-2 (I-SPARC; IJB-COVID-001) angela.loizidou@hubruxelles.be 2 2
22754 Brain metastasis Ahmad Hussein Awada Multiple Lilly I3Y-MC-JPBO Trial closed A phase II study of Abemaciclib in patients with brain metastases secondary to hormone receptor positive breast cancer, non-small cell lung cancer, or melanoma ahmad.awada@hubruxelles.be 2 2