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 Scientific publications

MicroRNA profiling and identification of let-7a as a target to prevent chemotherapy-induced primordial follicles apoptosis in mouse ovaries.

Authors : Alexandri C, Stamatopoulos B, Rothé F, Bareche Y, Devos M, Demeestere I
Year : 2019
Journal : Sci Rep
Volume : 9
Pages : 9636

Clinical significance of DNA methylation in chronic lymphocytic leukemia patients: results from 3 UK clinical trials.

Authors : Wojdacz TK, Amarasinghe HE, Kadalayil L, Beattie A, Forster J, Blakemore SJ, Parker H, Bryant D, Larrayoz M, Clifford R, Robbe P, Davis ZA, Else M, Howard DR, Stamatopoulos B, Steele AJ, Rosenquist R, Collins A, Pettitt AR, Hillmen P, Plass C, Schuh A, Catovsky D, Oscier DG, Rose-Zerilli MJJ, Oakes CC, Strefford JC
Year : 2019
Journal : Blood Adv
Volume : 3
Pages : 2474-2481

Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients.

Authors : Chi VLD, Garaud S, De Silva P, Thibaud V, Stamatopoulos B, Berehad M, Gu-Trantien C, Krayem M, Duvillier H, Lodewyckx JN, Willard-Gallo K, Sibille C, Bron D
Year : 2019
Journal : BMC Cancer
Volume : 19
Pages : 81

Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups.

Authors : Burns A, Alsolami R, Becq J, Stamatopoulos B, Timbs A, Bruce D, Robbe P, Vavoulis D, Clifford R, Cabes M, Dreau H, Taylor J, Knight SJL, Mansson R, Bentley D, Beekman R, Martín-Subero JI, Campo E, Houlston RS, Ridout KE, Schuh A
Year : 2018
Journal : Leukemia
Volume : 32
Pages : 332-342

The light chain IgLV3-21 defines a new poor prognostic subgroup in Chronic Lymphocytic Leukemia: results of a multicenter study.

Authors : Stamatopoulos B, Smith T, Crompot E, Pieters K, Clifford R, Mraz M, Robbe P, Burns A, Timbs A, Bruce DR, Hillmen P, Meuleman N, Mineur P, Firescu R, Maerevoet M, de Wilde V, Efira AA, Philippé J, Verhasselt B, Offner F, Sims D, Heger A, Dreau H, Schuh A
Year : 2018
Journal : Clin Cancer Res
Volume : 24(20)
Pages : 5048-5057

Targeted deep sequencing reveals clinically relevant subclonal IgHV rearrangements in chronic lymphocytic leukemia.

Authors : Stamatopoulos B, Timbs A, Bruce D, Smith T, Clifford R, Robbe P, Burns A, Vavoulis DV, Lopez L, Antoniou P, Mason J, Dreau H, Schuh A
Year : 2017
Journal : Leukemia
Volume : 31(4)
Pages : 837-45

Extracellular vesicles of bone marrow stromal cells rescue chronic lymphocytic leukemia B-cells from apoptosis, enhance their migration and induce gene expression modifications.

Authors : Crompot E, Van Damme M, Pieters K, Vermeersch M, Perez-Morga D, Mineur P, Maerevoet M, Meuleman N, Bron D, Lagneaux L, Stamatopoulos B
Year : 2017
Journal : Haematologica
Volume : 102(9)
Pages : 1594-1604

NCRI phase II study of CHOP in combination with ofatumumab in induction and maintenance in newly diagnosed Richter syndrome.

Authors : Eyre TA, Clifford R, Bloor A, Boyle L, Roberts C, Cabes M, Collins GP, Devereux S, Follows G, Fox CP, Gribben J, Hillmen P, Hatton CS, Littlewood TJ, McCarthy H, Murray J, Pettitt AR, Soilleux E, Stamatopoulos B, Love SB, Wotherspoon A, Schuh A
Year : 2016
Journal : Br J Haematol
Volume : 175(1)
Pages : 43-54

Characterization of TET and IDH gene expression in chronic lymphocytic leukemia: comparison with normal B cells and prognostic significance.

Authors : Van Damme M, Crompot E, Meuleman N, Maerevoet M, Mineur P, Bron D, Lagneaux L, Stamatopoulos B
Year : 2016
Journal : Clin Epigenetics
Volume : 8
Pages : 132

Immune impairments in multiple myeloma bone marrow mesenchymal stromal cells.

Authors : André T, Najar M, Stamatopoulos B, Pieters K, Pradier O, Bron D, Meuleman N, Lagneaux L
Year : 2015
Journal : Cancer Immunol. Immunother.
Volume : 64(2)
Pages : 213-24

Avoiding false positive antigen detection by flow cytometry on blood cell derived microparticles: the importance of an appropriate negative control.

Authors : Crompot E, Van Damme M, Duvillier H, Pieters K, Vermeesch M, Perez-Morga D, Meuleman N, Mineur P, Bron D, Lagneaux L, Stamatopoulos B
Year : 2015
Journal : PLoS ONE
Volume : 10(5)
Pages : e0127209

Opposite prognostic significance of cellular and serum circulating microRNA-150 in Chronic Lymphocytic Leukemia patients.

Authors : Stamatopoulos B, Van Damme M, Crompot E, Dessars B, El Housni H, Mineur P, Meuleman N, Bron D, Lagneaux L
Year : 2015
Journal : Mol. Med.
Volume : 21(1)
Pages : 123-33

Lipoprotein Lipase SNPs rs13702 and rs301 Correlate with Clinical Outcome in Chronic Lymphocytic Leukemia Patients.

Authors : Rombout A, Stamatopoulos B, Lagneaux L, Lust S, Offner F, Naessens E, Vanderstraeten H, Verhasselt B, Philippé J
Year : 2015
Journal : PLoS ONE
Volume : 10(3)
Pages : e0121526

Global histone deacetylase enzymatic activity is an independent prognostic marker associated with a shorter overall survival in chronic lymphocytic leukemia patients.

Authors : Van Damme M, Crompot E, Meuleman N, Mineur P, Dessars B, El Housni H, Bron D, Lagneaux L, Stamatopoulos B
Year : 2014
Journal : Epigenetics
Volume : 9(10)
Pages : 1374-81

In vivo production of mesenchymal stromal cells after injection of autologous platelet-rich plasma activated by recombinant human soluble tissue factor in the bone marrow of healthy volunteers.

Authors : Philippart P, Meuleman N, Stamatopoulos B, Najar M, Pieters K, De Bruyn C, Bron D, Lagneaux L
Year : 2014
Journal : Tissue Eng Part A
Volume : 20(1-2)
Pages : 160-70

Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells.

Authors : André T, Meuleman N, Stamatopoulos B, De Bruyn C, Pieters K, Bron D, Lagneaux L
Year : 2013
Journal : PLoS ONE
Volume : 8(3)
Pages : e59756

AMD3100 disrupts the cross-talk between chronic lymphocytic leukemia cells and a mesenchymal stromal or nurse-like cell -based microenvironment: preclinical evidence for its association with chronic lymphocytic leukemia treatments.

Authors : Stamatopoulos B, Meuleman N, De Bruyn C, Pieters K, Mineur P, Le Roy C, Saint-Georges S, Varin-Blank N, Cymbalista F, Bron D, Lagneaux L
Year : 2012
Journal : Haematologica
Volume : 97(4)
Pages : 608-615

HDAC isoenzyme expression is deregulated in chronic lymphocytic leukemia B-cells and has a complex prognostic significance.

Authors : Van Damme M, Crompot E, Meuleman N, Mineur P, Bron D, Lagneaux L, Stamatopoulos B
Year : 2012
Journal : Epigenetics
Volume : 7(12)
Pages : 1403-1412

A rapid, simple, and reproducible method for the isolation of mesenchymal stromal cells from Wharton's jelly without enzymatic treatment.

Authors : De Bruyn C, Najar M, Raicevic G, Meuleman N, Pieters K, Stamatopoulos B, Delforge A, Bron D, Lagneaux L
Year : 2011
Journal : Stem Cells Dev.
Volume : 20
Pages : 3

The source of human mesenchymal stromal cells influences their TLR profile as well as their functional properties.

Authors : Raicevic G, Najar M, Stamatopoulos B, De Bruyn C, Meuleman N, Bron D, Toungouz M, Lagneaux L
Year : 2011
Journal : Cell. Immunol.
Volume : 270(2)
Pages : 207-16