NK cells and monocytes modulate primary HTLV-1 infection.

Authors : Moles R, Sarkis S, Galli V, Omsland M, Artesi M, Bissa M, McKinnon K, Brown S, Hahaut V, Washington-Parks R, Welsh J, Venzon DJ, Gutowska A, Doster MN, Breed MW, Killoran KE, Kramer J, Jones J, Moniuszko M, Van den Broeke A, Pise-Masison CA, Franchini G
Year : 2022
Journal : PLoS Pathog
Volume : 18
Pages : e1010416

Targeted deep sequencing reveals clonal and subclonal mutational signatures in Adult T-cell leukemia/lymphoma and defines an unfavorable indolent subtype. (THE 3 LAST AUTHORS CONTRIBUTED EQUALLY)

Authors : Marçais A, Lhermitte L, Artesi M, Laurent C, Durkin K, Hahaut V, Rosewick N, Suarez F, Sibon D, Cheminant M, Avettand-Fenoel V, Bruneau J, Georges M, Pique C, Asnafi V, Hermine O, Van den Broeke A
Year : 2021
Journal : Leukemia
Volume : 35
Pages : 764-776

The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape.

Authors : Vandermeulen C, OGrady T, Wayet J, Galvan B, Maseko S, Cherkaoui M, Desbuleux A, Coppin G, Olivet J, Ben Ameur L, Kataoka K, Ogawa S, Hermine O, Marcais A, Thiry M, Mortreux F, Calderwood MA, Van Weyenbergh J, Peloponese JM, Charloteaux B, Van den Broeke A, Hill DE, Vidal M, Dequiedt F, Twizere JC
Year : 2021
Journal : PLoS Pathog
Volume : 17
Pages : e1009919

PCIP-seq: simultaneous sequencing of integrated viral genomes and their insertion sites with long reads.

Authors : Artesi M, Hahaut V, Cole B, Lambrechts L, Ashrafi F, Marçais A, Hermine O, Griebel P, Arsic N, van der Meer F, Burny A, Bron D, Bianchi E, Delvenne P, Bours V, Charlier C, Georges M, Vandekerckhove L, Van den Broeke A, Durkin K
Year : 2021
Journal : Genome Biol
Volume : 22
Pages : 97

Colour-sidedness in Gloucester cattle is associated with a complex structural variant impacting regulatory elements downstream of KIT.

Authors : Artesi M, Tamma N, Deckers M, Karim L, Coppieters W, Van den Broeke A, Georges M, Charlier C, Durkin K
Year : 2020
Journal : Anim Genet
Volume : 51
Pages : 461-465

An Improved Sequencing-Based Bioinformatics Pipeline to Track the Distribution and Clonal Architecture of Proviral Integration Sites.

Authors : Rosewick N, Hahaut V, Durkin K, Artesi M, Karpe S, Wayet J, Griebel P, Arsic N, Marçais A, Hermine O, Burny A, Georges M, Van den Broeke A
Year : 2020
Journal : Front Microbiol
Volume : 11
Pages : 587306

Essential Role of Human T Cell Leukemia Virus Type 1 <i>orf-I</i> in Lethal Proliferation of CD4⁺ Cells in Humanized Mice.

Authors : Galli V, Nixon CC, Strbo N, Artesi M, de Castro-Amarante MF, McKinnon K, Fujikawa D, Omsland M, Washington-Parks R, Romero L, Caruso B, Durkin K, Brown S, Karim B, Vaccari M, Jacobson S, Zack JA, Van den Broeke A, Pise-Masison C, Franchini G
Year : 2019
Journal : J Virol
Volume : 93

Pooled CRISPR Inverse PCR sequencing (PCIP-seq): simultaneous sequencing of retroviral insertion points and the associated provirus in thousands of cells with long reads.

Authors : Artesi M, Hahaut V, Cole B, Lambrechts L, Ashrafi F, Marcais A, Hermine O, Griebel P, Arsic N, van der Meer L, Burny A, Bron D, Bianchi F, Delvenne P, Bours V, Charlier C, Georges M, Vandekerckhove L, Van den Broeke A, Durkin K
Year : 2019
Journal : bioRxiv
Volume : _
Pages : 558130

Adult T-cell leukaemia-lymphoma: Pathogeny and clinical recommendations.

Authors : Vercruyssen M, Van den Broeke A, Salaroli A, Nguyen P, de Wind A, Meuleman N, Bron D
Year : 2019
Journal : Belgian J Hematology
Volume : 10
Pages : 277-284

PDZ domain-binding motif of Tax sustains T-cell proliferation in HTLV-1-infected humanized mice.

Authors : Pérès E, Blin J, Ricci EP, Artesi M, Hahaut V, Van den Broeke A, Corbin A, Gazzolo L, Ratner L, Jalinot P, Duc Dodon M
Year : 2018
Journal : PLoS Pathog
Volume : 14
Pages : e1006933

Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis.

Authors : Rosewick N, Durkin K, Artesi M, Marçais A, Hahaut V, Griebel P, Arsic N, Avettand-Fenoel V, Burny A, Charlier C, Hermine O, Georges M, Van den Broeke A
Year : 2017
Journal : Nat Commun
Volume : 8
Pages : 15264

Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality.

Authors : Artesi M, Marçais A, Durkin K, Rosewick N, Hahaut V, Suarez F, Trinquand A, Lhermitte L, Asnafi V, Avettand-Fenoel V, Burny A, Georges M, Hermine O, Van den Broeke A
Year : 2017
Journal : Leukemia
Volume : 31
Pages : 2532-35

HTLV-1-induced leukotriene B4 secretion by T cells promotes T cell recruitment and virus propagation.

Authors : Percher F, Curis C, Pérès E, Artesi M, Rosewick N, Jeannin P, Gessain A, Gout O, Mahieux R, Ceccaldi PE, Van den Broeke A, Duc Dodon M, Afonso PV
Year : 2017
Journal : Nat Commun
Volume : 8
Pages : 15890

Characterization of novel Bovine Leukemia Virus (BLV) antisense transcripts by deep sequencing reveals constitutive expression in tumors and transcriptional interaction with viral microRNAs.

Authors : Durkin K, Rosewick N, Artesi M, Hahaut V, Griebel P, Arsic N, Burny A, Georges M, Van den Broeke A
Year : 2016
Journal : Retrovirology
Volume : 13
Pages : 33

In vivo characterizatio of the BLV miRNA cluster

Authors : Rodari A, Van Driessche B, Delacourt N, Vanhulle C, Burny A, Van den Broeke A, Rohr O, Van Lint C
Year : 2015
Journal : Retrovirology
Volume : 12(1
Pages : 11

HTLV-1/BLV antisense-RNA dependent host gene perturbation in pre-leukemic and leukemic clones

Authors : Rosewick N, Durkin K, Marcais A, Artesi M, Hahaut V, Herminne O, Charlier C, Georges M, Van den Broeke A
Year : 2015
Journal : Retrovirology
Volume : 12(1)
Pages : 44

Improving the methodology for the detection of proviral integration sites in the host genome via high throughput sequencing

Authors : Durkin K, Rosewick N, Herminne O, Georges M, Van den Broeke A
Year : 2015
Journal : Retrovirology
Volume : 12(1)
Pages : 51

Deep sequencing reveals abundant noncanonical retroviral microRNAs in B-cell leukemia/lymphoma.

Authors : Rosewick N, Momont M, Durkin K, Takeda H, Caiment F, Cleuter Y, Vernin C, Mortreux F, Wattel E, Burny A, Georges M, Van den Broeke A
Year : 2013
Journal : Proc. Natl. Acad. Sci. U.S.A.
Volume : 110(6)
Pages : 2306-11

High-throughput sequencing reveals novel microRNAs in a retrovirus-induced ovine model of leukemia. (TEXTBOOK Keystone meeting MicroRNAs and non-coding RNAs in cancer, Banff, Canada, February 10-16, 2011)

Authors : Rosewick N, Dehouck C, Cleuter Y, Caiment F, Georges M, Martiat P, Burny A, Van den Broeke A
Year : 2011
Journal : Book
Volume : -
Pages : -

Chromatin disruption in the promoter of bovine leukemia virus during transcriptional activation.

Authors : Colin L, Dekoninck A, Reichert M, Calao M, Merimi M, Van den Broeke A, Vierendeel V, Cleuter Y, Burny A, Rohr O, Van Lint C
Year : 2011
Journal : Nucleic Acids Res.
Volume : 39(22)
Pages : 9559-73