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The Institut Bordet Clinical Haematology Department specialises in determining and treating diseases of the blood.

The Institut Bordet is committed to the treatment of these diseases and to offering patients high-quality, individual treatment.

In addition to the traditional approach to blood diseases, the Institut is also engaged in the development of innovative and complex techniques and therapies.

The Institut’s mission covers three main university fields: clinical, research and teaching.

The multidisciplinary nature of the Department, in both its diagnostic and therapeutic approaches, forms an integral part of all decisions concerning the patient.

Research projects

Participation of the Hematology Department in research projects with the following laboratories :

EXPERIMENTAL HAEMATOLOGY LABORATORY (HEMEXP)
CLINICAL CELLULAR THERAPY RESEARCH LABORATORY (LTCC)

 

Project 1

The prognostic value of cognitive function, biomarkers of ageing and clinical factors in elderly patients with malignant haemopathy admitted for chemotherapy (Dominique Bron, MD, PhD)
  • Project leader : Dominique Bron
  • Collaborations : H. Wildiers, M. Delforge (KUL)
  • Funding : Télévie, FNRS, Fonds Yvonne Boël

Project 2

Interculturality and Transplantation  

Project 3

Role of radio-immunotherapy in myeloma

Project 4

Protocoles de recherche clinique académiques et pharmaceutiques
  • Project leaders : Dominique Bron and colleagues
  • Funding : Fonds Ariane, Pharma

Our team

Head of Department
Prof Dominique Bron - Haematological Medicine (rare lymphoma and chronic lymphoid leukaemia)

Heads of Clinic
- Prof Nathalie Meuleman - Haematological Medicine (multiple myeloma and plasmocytary disorders, autografts)
- Prof Philippe Lewalle - Haematological Medicine (myeloproliferative syndrome, chronic myeloid leukaemia and
allogeneic transplants)
- Prof Sebastian Wittnebel - Haematological Medicine (leukaemia, myelodysplasia, new drugs and
allogeneic transplants)
- Dr Marie Maerevoet - Haematological Medicine (lymphomas and lymphoproliferative disorders, new drugs,
autografts)
- Dr Cécile Springael -
Haematological Medicine (T lymphomas and rare lymphomas)

Consultant
- Dr Phuong Huynh
-
General practitioner (ability of autologous and allogeneic donors to be collected in stem cells and lymphocytes, haemovigilance)

Resident
- Dr Marie Vercruyssen - Haematological Medicine (multiple myeloma and plasmocytic disorders, autografts)
- Dr Chloé Spilleboudt
Haematological Medicine (leukemias, myelodysplasias and allogeneic transplantations)
- Dr
Adriano SalaroliHaematological Medicine (myeloproliferative syndromes, chronic myeloid leukemia, leukemia, myelodysplasia and allogeneic transplantation)

Head Nursing (Tel : +32 (0)2 541 33 55)
Patrick Crombez

Nursing «coordinator of allografts » (Tel : +32 (0)2 541 33 30)
- Marie-France Jaivenois

Nurses (health care coordinators) (Tel : +32 (0)2 541 73 94)
- Sophie Delaunois
- Zilfi Balci

Cytapheresis unit and Stem Cell Collection (Tel : +32 (0)2 541 32 11)
Philippe Lewalle - Responsible physician
- Adriano Salaroli - Resident
- Corine Mal - Nurse
- Walter Bellemans - Nurse
- Munteanu Nicoleta - Nurse
- Olivier Mugema - Nurse

Transplantation Coordination (Tel : +32 (0)2 541 32 12)
- Sandra Michiels - Coordinator
- Redouane Rouas - Suppleant

Data Managing Unit
- Anne De Meuter - Head Nurse (Tel : +32 (0)2 541 72 05)
- Dominique De Poorter - Nurse (Tel : +32 (0)2 541 35 98)
- Sabrina Costantini - Administrative (Tel : +32 (0)2 541 37 55)
- Delphine Leva - Administrative (Tel : +32 (0)2 541 33 57)
- Gregory Rios - Nurse (Tel : +32 (0)2 541 36 47)

Quality Cell
- Aurélie Timmermans (Tel +32 (0)2 541 72 25)
-
 Olivier Carabin (Tel +32 (0)2 541 37 26)

Secretariat 
- Sabine Ackermans (Administration) - Tel : +32 (0)2 541 37 28
- Jennifer Marinus (Consultation) - Tel : +32 (0)2 541 36 84
- Nancy Martin (Consultation) - Tel : +32 (0)2 541 38 78

 Scientific publications

A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial.

Authors : Facon T, Dimopoulos MA, Meuleman N, Belch A, Mohty M, Chen WM, Kim K, Zamagni E, Rodriguez-Otero P, Renwick W, Rose C, Tempescul A, Boyle E, Manier S, Attal M, Moreau P, Macro M, Leleu X, Lorraine Chretien M, Ludwig H, Guo S, Sturniolo M, Tinel A, Silvia Monzini M, Costa B, Houck V, Hulin C, Yves Mary J
Year : 2020
Journal : Leukemia
Volume : 34
Pages : 224-233

Reactive stroma and trastuzumab resistance in HER2-positive early breast cancer.

Authors : Sonnenblick A, Salmon-Divon M, Salgado R, Dvash E, Pondé N, Zahavi T, Salmon A, Loibl S, Denkert C, Joensuu H, Ameye L, Van den Eynden G, Kellokumpu-Lehtinen PL, Azaria A, Loi S, Michiels S, Richard F, Sotiriou C
Year : 2020
Journal : Int J Cancer

Allogeneic stem cell transplantation for acquired pure red cell aplasia.

Authors : Halkes C, de Wreede LC, Knol C, Simand C, Aljurf M, Tbakhi A, Vazquez L, Bloor A, Wagner-Drouet E, Vural F, Bodova I, Isaksson C, Diaz MÁ, Gruhn B, Snowden J, Arat M, Bazarbachi A, Spilleboudt C, Kulagin A, Marsh JC, Passweg J, Risitano AM, Peffault de Latour R, Dufour C
Year : 2019
Journal : Am J Hematol
Volume : 94
Pages : E294-E296

Oral Selinexor-Dexamethasone for Triple-Class Refractory Multiple Myeloma.

Authors : Chari A, Vogl DT, Gavriatopoulou M, Nooka AK, Yee AJ, Huff CA, Moreau P, Dingli D, Cole C, Lonial S, Dimopoulos M, Stewart AK, Richter J, Vij R, Tuchman S, Raab MS, Weisel KC, Delforge M, Cornell RF, Kaminetzky D, Hoffman JE, Costa LJ, Parker TL, Levy M, Schreder M, Meuleman N, Frenzel L, Mohty M, Choquet S, Schiller G, Comenzo RL, Engelhardt M, Illmer T, Vlummens P, Doyen C, Facon T, Karlin L, Perrot A, Podar K, Kauffman MG, Shacham S, Li L, Tang S, Picklesimer C, Saint-Martin JR, Crochiere M, Chang H, Parekh S, Landesman Y, Shah J, Richardson PG, Jagannath S
Year : 2019
Journal : N Engl J Med
Volume : 381
Pages : 727-738

Mesenchymal stromal cells and natural killer cells: a complex story of love and hate.

Authors : Najar M, Fayyad-Kazan M, Merimi M, Burny A, Bron D, Fayyad-Kazan H, Meuleman N, Lagneaux L
Year : 2019
Journal : Curr Stem Cell Res Ther
Volume : 14(1)
Pages : 14-21