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Apheresis Unit (Hematology)

Apherisis is a procedure that makes it possible to separate the various elements of the blood, in particular: 

  • the plasma (therapeutic plasmapherisis),
  • the red corpuscles (therapeutic erythropheresis),
  • the white corpuscles (therapeutic leucapheresis),
  • the hematopoietic stem cells (cytapheresis), essential for both analogous transplants (using cells taken from the patient) and allogenic transplants (using the cells of another donor). 

Apheresis is a technique of extraction by centrifugation in an extracorporeal blood circuit (CEC). The components not collected are reinjected into the donor. 

The Apheresis Unit at the Jules Bordet Institute receives, for the ULB-IRIS network as a whole, patients likely to benefit from the collection of stem cells. The Unit works in close cooperation with the various autotransplant centres for adults and with the Children's Hospital (HUDERF). 

We have been practicing apheresis in our service since 1970, with a nursing and technical staff trained especially for the purpose. Two doctors and four nurses are available and ensure the continuity of the medical care, in cooperation with the hematology service as a whole. The Unit has an emergency service that operates 24 hours a day. 

The harvest, handling and conservation of the hematopoietic stem cells is in accordance with good practices. Since 2009 we have been accredited under the inspection programme (JACIE, the "Joint Accreditation Committee of the ISCT and EBMT" ) which makes it possible to improve quality within the various teams involved in carrying out the hematopoietic transplants.  

The Apheresis Unit at the Jules Bordet Institute also gives our patients access to treatment using photopheresis. This treatment is indicated for Graft Versus Host Disease that does not respond to the standard treatment and in certain cases of skin lymphomas. 


Research projects


Project 1

A Phase II study to assess the safety and the efficacy of extracorporeal photopheresis using the Theraflex ECP™ for patients with refractory chronic GVHD

Our team

  • Responsible Physician
  • Physicians
  • Nurse(s)
    • Maud Caudron, head
    • Carmen Ayquipa Casas
    • Clotilde Aubrun
    • Denise Duthoit
    • Nicoleta Munteanu
    • Walter Bellemans
  • Qualitician
    • Aurélie Timmermans, head
    • Sfia Bourdji, Coordinator
    • Celia Meurillon, Coordinator
  • Secretary
    • Maryline Horvath


 Scientific publications

Linking clinical and population-based data in older patients with cancer in Belgium: Feasibility and clinical outcomes.

Authors : Depoorter V, Vanschoenbeek K, Decoster L, De Schutter H, Debruyne PR, De Groof I, Bron D, Cornélis F, Luce S, Focan C, Verschaeve V, Debugne G, Langenaeken C, Van den Bulck H, Goeminne JC, Teurfs W, Jerusalem G, Schrijvers D, Petit B, Rasschaert M, Praet JP, Vandenborre K, Milisen K, Flamaing J, Kenis C, Verdoodt F, Wildiers H
Year : 2023
Journal : J Geriatr Oncol
Pages : 101428

Potential of Mesenchymal Stromal Cell-Derived Extracellular Vesicles as Natural Nanocarriers: Concise Review.

Authors : Draguet F, Bouland C, Dubois N, Bron D, Meuleman N, Stamatopoulos B, Lagneaux L
Year : 2023
Journal : Pharmaceutics
Volume : 15

HTLV-1-related adult T-cell leukemia/lymphoma: insights in early detection and management.

Authors : Wolf S, Vercruyssen M, Cook L
Year : 2022
Journal : Curr Opin Oncol
Volume : 34
Pages : 446-453

Effectiveness and Safety of Ibrutinib for Chronic Lymphocytic Leukemia in Routine Clinical Practice: 3-Year Follow-up of the Belgian Ibrutinib Real-World Data (BiRD) Study.

Authors : Janssens A, Berneman ZN, Offner F, Snauwaert S, Mineur P, Vanstraelen G, Meers S, Spoormans I, Bron D, Vande Broek I, Van Bogaert C, De Beleyr B, Smet A, Nielsen L, Wapenaar R, André M
Year : 2022
Journal : Clin Hematol Int
Volume : 4
Pages : 133-143

Mesenchymal Stem/Stromal Cells as a Therapeutic Tool in Cell-Based Therapy and Regenerative Medicine: An Introduction Expertise to the Topical Collection.

Authors : Merimi M, Fahmi H, De Kock J, Beguin C, Burny A, Moll G, Poggi A, Najar M
Year : 2022
Journal : Cells
Volume : 11