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Mantle Cell Lymphoma

Health problems

Mantle cell lymphoma

Mantle cell lymphoma is a type of cancer that affects the B lymphocytes that are a form of white blood cell. The lymphoma takes its name from the “mantle zone” of the lymph nodes which is where these cells are normally found. 

A lymphoma of this type develops when the B lymphocytes undergo genetic modifications that causes them to divide uncontrollably. These abnormal cells then accumulate in the lymph nodes, bone marrow, spleen and sometimes in the blood. This disturbs the normal functioning of the immune system. 

The symptoms of mantle cell lymphoma can be very varied and often non-specific, making diagnosis difficult. Common symptoms include 

  • Swelling of lymph nodes: often painless, generally in the neck,      armpits and groin. 
  • Extreme fatigue: not linked to physical exertion.
  • Fever: without apparent cause.
  • Abundant night time sweating.
  • Inexplicable weight loss.
  • Abdominal pain and digestive problems: such as nausea or diarrhoea.