Alle verbonden artikelen

Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity.

Auteurs : Van Keymeulen A, Lee MY, Ousset M, Brohée S, Rorive S, Giraddi RR, Wuidart A, Bouvencourt G, Dubois C, Salmon I, Sotiriou C, Phillips WA, Blanpain C
Jaar : 2015
Journal : Nature
Volume : 525(7567
Pagina's : 119-23

Constitutive phosphorylated STAT3-associated gene signature is predictive for trastuzumab resistance in primary HER2-positive breast cancer.

Auteurs : Sonnenblick A, Brohée S, Fumagalli D, Vincent D, Venet D, Ignatiadis M, Salgado R, Van den Eynden G, Rothé F, Desmedt C, Neven P, Loibl S, Denkert C, Joensuu H, Loi S, Sirtaine N, Kellokumpu-Lehtinen PL, Piccart-Gebhart M, Sotiriou C
Jaar : 2015
Journal : BMC Med
Volume : 13(1)
Pagina's : 177

Subclonal diversification of primary breast cancer revealed by multiregion sequencing.

Auteurs : Yates LR, Gerstung M, Knappskog S, Desmedt C, Gundem G, Van Loo P, Aas T, Alexandrov LB, Larsimont D, Davies H, Li Y, Ju YS, Ramakrishna M, Haugland HK, Lilleng PK, Nik-Zainal S, McLaren S, Butler A, Martin S, Glodzik D, Menzies A, Raine K, Hinton J, Jones D, Mudie LJ, Jiang B, Vincent D, Greene-Colozzi A, Adnet PY, Fatima A, Maetens M, Ignatiadis M, Stratton MR, Sotiriou C, Richardson AL, Lønning PE, Wedge DC, Campbell PJ
Jaar : 2015
Journal : Nat. Med.
Volume : 21(7)
Pagina's : 751-9

Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab: A Secondary Analysis of the NeoALTTO Trial.

Auteurs : Salgado R, Denkert C, Campbell C, Savas P, Nucifero P, Aura C, de Azambuja E, Eidtmann H, Ellis CE, Baselga J, Piccart-Gebhart M, Michiels S, Bradbury I, Sotiriou C, Loi S
Jaar : 2015
Journal : JAMA Oncol
Volume : 1(4)
Pagina's : 448-54

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells.

Auteurs : Ju YS, Tubio JM, Mifsud W, Fu B, Davies HR, Ramakrishna M, Li Y, Yates L, Gundem G, Tarpey PS, Behjati S, Papaemmanuil E, Martin S, Fullam A, Gerstung M, Nangalia J, Green AR, Caldas C, Borg Å, Tutt A, Lee MT, van t Veer LJ, Tan BK, Aparicio S, Span PN, Martens JW, Knappskog S, Vincent-Salomon A, Borresen-Dale AL, Eyfjord JE, Flanagan AM, Foster C, Neal DE, Cooper C, Eeles R, Lakhani SR, Desmedt C, Thomas G, Richardson AL, Purdie CA, Thompson AM, McDermott U, Yang F, Nik-Zainal S, Campbell PJ, Stratton MR
Jaar : 2015
Journal : Genome Res
Volume : 25(6)
Pagina's : 814-24

Uncovering the genomic heterogeneity of multifocal breast cancer.

Auteurs : Desmedt C, Fumagalli D, Pietri E, Zoppoli G, Brown D, Nik-Zainal S, Gundem G, Rothé F, Majjaj S, Garuti A, Carminati E, Loi S, Van Brussel T, Boeckx B, Maetens M, Mudie L, Vincent D, Kheddoumi N, Serra L, Massa I, Ballestrero A, Amadori D, Salgado R, de Wind A, Lambrechts D, Piccart-Gebhart M, Larsimont D, Campbell PJ, Sotiriou C
Jaar : 2015
Journal : J. Pathol.
Volume : 236(4)
Pagina's : 457-66

Predicting Anthracycline Benefit: TOP2A and CEP17-Not Only but Also.

Auteurs : Bartlett JM, McConkey CC, Munro AF, Desmedt C, Dunn JA, Larsimont D, O Malley FP, Cameron DA, Earl HM, Poole CJ, Shepherd LE, Cardoso F, Jensen MB, Caldas C, Twelves CJ, Rea DW, Ejlertsen B, Di Leo A, Pritchard KI
Jaar : 2015
Journal : J. Clin. Oncol.
Volume : 33(15)
Pagina's : 1680-7

New approaches for improving outcomes in breast cancer in Europe.

Auteurs : Di Leo A, Curigliano G, Diéras V, Malorni L, Sotiriou C, Swanton C, Thompson A, Tutt A, Piccart-Gebhart M
Jaar : 2015
Journal : Breast
Volume : 24(4)
Pagina's : 321-330

No significant viral transcription detected in whole breast cancer transcriptomes.

Auteurs : Fimereli D, Gacquer D, Fumagalli D, Salgado R, Rothé F, Larsimont D, Sotiriou C, Detours V
Jaar : 2015
Journal : BMC Cancer
Volume : 15(null)
Pagina's : 147

RANK-ligand (RANKL) expression in young breast cancer patients and during pregnancy.

Auteurs : Azim HA, Peccatori FA, Brohée S, Branstetter D, Loi S, Viale G, Piccart-Gebhart M, Dougall WC, Pruneri G, Sotiriou C
Jaar : 2015
Journal : Breast Cancer Res
Volume : 17
Pagina's : 24

PIK3CA Mutations Are Associated With Decreased Benefit to Neoadjuvant Human Epidermal Growth Factor Receptor 2-Targeted Therapies in Breast Cancer.

Auteurs : Majewski IJ, Nuciforo P, Mittempergher L, Bosma AJ, Eidtmann H, Holmes E, Sotiriou C, Fumagalli D, Jimenez J, Aura C, Prudkin L, Díaz-Delgado MC, de la Peña L, Loi S, Ellis C, Schultz N, de Azambuja E, Harbeck N, Piccart-Gebhart M, Bernards R, Baselga J
Jaar : 2015
Journal : J. Clin. Oncol.
Volume : 33(12)
Pagina's : 1334-9

Transfer of clinically relevant gene expression signatures in breast cancer: from Affymetrix microarray to Illumina RNA-Sequencing technology.

Auteurs : Fumagalli D, Blanchet-Cohen A, Brown D, Desmedt C, Gacquer D, Michiels S, Rothé F, Majjaj S, Salgado R, Larsimont D, Ignatiadis M, Maetens M, Piccart-Gebhart M, Detours V, Sotiriou C, Haibe-Kains B
Jaar : 2014
Journal : BMC Genomics
Volume : 15(1)
Pagina's : 1008

Deciphering clonality in aneuploid tumors using SNP array and sequencing data.

Auteurs : Lönnstedt IM, Caramia F, Li J, Fumagalli D, Salgado R, Rowan A, Salm M, Kanu N, Savas P, Horswell S, Gade S, Loibl S, Neven P, Sotiriou C, Swanton C, Loi S, Speed TP
Jaar : 2014
Journal : Genome Biol.
Volume : 15(9)
Pagina's : 470

Is the differentiation into molecular subtypes of breast cancer important for staging, local and systemic therapy, and follow up?

Auteurs : Sonnenblick A, Fumagalli D, Sotiriou C, Piccart-Gebhart M
Jaar : 2014
Journal : Cancer Treat Rev
Volume : 40(9)
Pagina's : 1089-95

PIK3CA mutations are associated with lower rates of pathologic complete response to anti-human epidermal growth factor receptor 2 (her2) therapy in primary HER2-overexpressing breast cancer.

Auteurs : Loibl S, Von Minckwitz G, Schneeweiss A, Paepke S, Lehmann A, Rezai M, Zahm DM, Sinn P, Khandan F, Eidtmann H, Dohnal K, Heinrichs C, Huober J, Pfitzner B, Fasching PA, Andre F, Lindner JL, Sotiriou C, Dykgers A, Guo S, Gade S, Nekljudova V, Loi S, Untch M, Denkert C
Jaar : 2014
Journal : J. Clin. Oncol.
Volume : 32(29)
Pagina's : 3212-20

New Strategies in Breast Cancer: The Significance of Molecular Subtypes in Systemic Adjuvant Treatment for Small T1a,bN0M0 Tumors.

Auteurs : Sonnenblick A, Fumagalli D, Azim HA, Sotiriou C, Piccart-Gebhart M
Jaar : 2014
Journal : Clin Cancer Res
Volume : 20(24)
Pagina's : 6242-6

The AURORA initiative for metastatic breast cancer.

Auteurs : Zardavas D, Maetens M, Irrthum A, Goulioti T, Engelen K, Fumagalli D, Salgado R, Aftimos P, Saini KS, Sotiriou C, Campbell P, Dinh P, Von Minckwitz G, Gelber Rd, Dowsett M, Di Leo A, Cameron D, Baselga J, Gnant M, Goldhirsch A, Norton L, Piccart-Gebhart M
Jaar : 2014
Journal : Br J Cancer
Volume : 111(10)
Pagina's : 1881-7

Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancer.

Auteurs : Rothé F, Laes JF, Lambrechts D, Smeets D, Vincent D, Maetens M, Fumagalli D, Michiels S, Drisis S, Moerman C, Detiffe JP, Larsimont D, Awada A, Piccart-Gebhart M, Sotiriou C, Ignatiadis M
Jaar : 2014
Journal : Ann Oncol
Volume : 25(10)
Pagina's : 1959-65

Regulation of DNA Methylation Patterns by CK2-Mediated Phosphorylation of Dnmt3a.

Auteurs : Deplus R, Blanchon L, Rajavelu A, Boukaba A, Defrance M, Luciani J, Rothé F, Dedeurwaerder S, Denis H, Brinkman AB, Simmer F, Müller F, Bertin B, Berdasco M, Putmans P, Calonne E, Litchfield DW, de Launoit Y, Jurkowski TP, Stunnenberg HG, Bock C, Sotiriou C, Fraga MF, Esteller M, Jeltsch A, Fuks F
Jaar : 2014
Journal : Cell Rep
Volume : 8(3)
Pagina's : 743-753

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

Auteurs : Tubio JM, Li Y, Ju YS, Martincorena I, Cooke SL, Tojo M, Gundem G, Pipinikas CP, Zamora J, Raine K, Menzies A, Roman-Garcia P, Fullam A, Gerstung M, Shlien A, Tarpey PS, Papaemmanuil E, Knappskog S, Van Loo P, Ramakrishna M, Davies HR, Wedge DC, Teague JW, Butler AP, Nik-Zainal S, Alexandrov L, Behjati S, Yates LR, Bolli N, Mudie L, Hardy C, Martin S, McLaren S, + collaborators (among others :, Larsimont D, Desmedt C, Sotiriou C, Campbell PJ
Jaar : 2014
Journal : Science
Volume : 345(6196)
Pagina's : 1251343