The Institut Bordet Medical Oncology Clinic has a number of roles:
- diagnosis and therapeutic care of patients with solid tumours
- overseeing administration of cancer medication for in-patients and out-patients
- monitoring patients during and after their treatment.
The Clinic takes a multidisciplinary approach. Therapeutic decisions are made in consultation with other specialist doctors and healthcare professionals involved in the patient’s care.
The aim is that patients should be monitored in all respects, including psychologically.
The Medical Oncology Clinic forms an integral part of the Department of Medicine. It is also very active in clinical research (particularly in the development of new medication) and translational research. At the Clinic, research is integrated into the care provided, enabling patients to benefit from the latest diagnostic and therapeutic advances, well before these become part of clinical routine.
The Medical Oncology Clinic is divided into 12 sectors:
- thoracic oncology
- urogenital oncology
- breast oncology
- innovative treatments
- endocrine tumour oncology
- bone and soft tissue tumour oncology
- gynaecological oncology
- digestive oncology
- cervico-facial oncology
- skin tumour oncology
- central nervous system oncology.
The Medical Oncology Clinic works in close collaboration with the Institut Bordet Clinical Trials Conduct Unit (CTCU). This unit, which is responsible for the development of new drugs and innovative approaches to care, handles phase I, II and III clinical studies in tumours. The CTCU is made up of research nurses, clinical research associates and data managers who, with research doctors, closely monitor patients taking part in clinical trials.
The Institut’s different research laboratories are also closely linked to the Medical Oncology Clinic. Their principal aim is to identify predictive marker molecules (indicating probability of response to a given treatment) and/or prognosis (chances of a cure) as part of the development of breast cancer treatments.
Recently, the Oncodistinct research network was created. This network brings together numerous researchers who share a common vision of innovative clinical research. The aim of the network is to accelerate the personalisation of treatment and the development of innovative treatments while also promoting a multidisciplinary approach to research and care.
The Institut Bordet Medical Oncology Clinic plays an important role in education, both in Belgium and abroad. Within the hospital, the Clinic’s medical team supervises the training of young doctors and medical students specialising in oncology. Always keen to promote quality training, the Clinic also welcomes many doctors from abroad as part of its Fellowship Programme.
AURORA Programme aimed at understanding the molecular characteristics of recurrent and metastatic breast cancer early in the evolution of metastatic disease.
NeoRHEA Clinical Study
- Project holder : Michael Ignatiadis
- Collaboration(s) : Belgian Hospitals and Oncology Centres
- Funding (or) Support : Pfizer
Head of the Medical Oncology Clinic
Pr A. Awada
Dr L. Dal Lago
Dr Y. Lalami
Central Nervous System Oncology
Pr E. de Azambuja
Pr J. Klastersky (médecine interne/oncologie)
Dr A. Covas (gastroentérologie/oncologie digestive)
Dr Z. El Ali (oncologie médicale)
Dr S. Latifyan (oncologie médicale)
Dr D. Levacq (oncologie médicale)
Choice of chemotherapy regimen for early HER2-positive breast cancer in elderly patients.
Authors : Pondé N, de Azambuja E
Year : 2018
Journal : Chin Clin Oncol
Volume : 7(1)
Pages : 4
Efficacy of Anti-HER2 Agents in Combination With Adjuvant or Neoadjuvant Chemotherapy for Early and Locally Advanced HER2-Positive Breast Cancer Patients: A Network Meta-Analysis.
Authors : Debiasi M, Polanczyk CA, Ziegelmann P, Barrios C, Cao H, Dignam JJ, Goss P, Bychkovsky B, Finkelstein DM, Guindalini RS, Filho P, Albuquerque C, Reinert T, de Azambuja E, Olopade O
Year : 2018
Journal : Front Oncol
Volume : 8
Pages : 156
Postmastectomy Radiation Therapy in Women with T1-T2 Tumors and 1 to 3 Positive Lymph Nodes: Analysis of the Breast International Group 02-98 Trial.
Authors : Zeidan YH, Habib JG, Ameye L, Paesmans M, de Azambuja E, Gelber Rd, Campbell I, Nordenskjöld B, Gutiérez J, Anderson M, Lluch A, Gnant M, Goldhirsch A, Di Leo A, Joseph DJ, Crown J, Piccart-Gebhart M, Francis PA
Year : 2018
Journal : Int J Radiat Oncol Biol Phys
Volume : 101(2)
Pages : 316-324.
Trastuzumab versus observation for HER2 non amplified early breast cancer with Circulating Tumor Cells (EORTC 90091-10093, BIG 1-12, Treat CTC): A randomized phase 2 trial.
Authors : Ignatiadis M, Litière S, Rothe F, Riethdorf S, Proudhon C, Fehm T, Aalders K, Forstbauer H, Fasching P, Brain E, Vuylsteke P, Guardiola E, Lorenz R, Pantel K, Tryfonidis K, Janni W, Piccart M, Sotiriou C, Rack B, Pierga JY
Year : 2018
Journal : Ann Oncol
Association of p27 and cyclin D1 expression and benefit from adjuvant trastuzumab treatment in HER2-positive early breast cancer: a TransHERA study.
Authors : Filipits M, Dafni U, Gnant M, Polydoropoulou V, Hills M, Kiermaier A, de Azambuja E, Larsimont DP, Rojo F, Viale G, Toi M, Harbeck N, Pritchard KI, Gelber Rd, Dinh P, Zardavas D, Leyland-Jones B, Piccart-Gebhart M, Dowsett M
Year : 2018
Journal : Clin Cancer Res
Volume : 24(13)
Pages : 3079-3086