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Radiotherapy remains one of the 3 pillars of treatment for patients affected by cancer. Half of all patients will undergo radiotherapy at one time or another. Radiotherapy may be used to treat cancer, improve quality of life and even to alleviate certain types of pain.

Radiotherapy uses the properties of ionizing radiation. Recent technological advances and a better understanding of the interaction between radiation and tumours has led to increasingly more effective equipment, in terms of both medical imaging (CT scan, MRI and PET scan) and radiotherapy.

Research projects

  

Project 1

CHEckpoint inhibition in combination with an immunoboost of External body Radiotherapy in Solid tumors: CHEERS-trial

Project 2

PEACE V: A randomized phase II trial for the Salvage Treatment of OligoRecurrent nodal prostate cancer Metastases (STORM)

Project 3

Phase IIIb randomized trial comparing irradiation plus long term adjuvant androgen deprivation with GnRH antagonist versus GnRH agonist plus flare protection in patients with very high risk localized or locally advanced prostate cancer. A joint study of the EORTC ROG and GUCG PEGASUS

Project 4

Radiation versus observation following surgical resection of atypical meningioma: a randomized controlled trial (The ROAM trial) EORTC protocol 1308-ROG-BTG
  • Project leader : Philippe Martinive
  • Funding : EORTC Cancer Research Fund / National Health System (UK)
  • Collaboration : EORTC

 

Project 5

A phase III trial of marizomib in combination with standard temozolomide-based radiochemotherapy versus standard temozolomide-based radiochemotherapy alone in patients with newly diagnosed glioblastoma
  • Project leader : Prof. Lefranc (Erasme) – Philippe Martinive (IJB)
  • Funding : EORTC Cancer Research Fund
  • Collaboration : EORTC

Projet 6

A prospective randomized phase 2 study of dose and volume de-escalation in prophylactic nodal irradiation of contralateral neck by sentinel lymph nodes mapping in unilaterally node positive head and neck squamous cell carcinomas

Team

Head of Department
Prof Dirk Van Gestel : ENT tumours, skin tumours, non-malignant tumours, sarcomas, breast tumours.

Senior Registrars
Dr Sylvie Beauvois : ENT tumours
Prof. Philippe Martinive : neurological and pediatric tumors
Prof. Luigi Moretti : digestive and thoracic tumours
Dr Catherine Philippson : breast tumours, curietherapy
Dr Martine Roelandts : thoracic tumours, lymphomas, skin tumours
Prof. Honorary Paul Van Houtte : thoracic and non-malignant tumours, curietherapy

The Team
Dr Adèle Baize : gynaecological tumours and curietherapy
Dr Alex De Caluwé : breast tumours, gynaecological tumours, curietherapy
Dr Antoine Desmet : breast, skin tumors and curietherapy
Dr Tatiana Dragan : ENT tumours, sarcomas (tumours of the central nervous system)
Dr François-Xavier Otte : digestive tumours, urological tumours
Dr Robbe Van den Begin : oligometastatic, pelvic and digestive tumors

Secretariat
Mrs Carine Top
Mrs Carine Vandevelde

 Scientific publications

Evolution of self-perceived swallowing function, tongue strength and swallow-related quality of life during radiotherapy in head and neck cancer patients.

Authors : Van den Steen L, Van Gestel D, Vanderveken O, Vanderwegen J, Lazarus C, Daisne JF, Van Laer C, Specenier P, Van Rompaey D, Mariën S, Lawson G, Chantrain G, Gauthier D, Van den Weyngaert D, Cvilic S, Beauvois S, Allouche J, Delacroix L, Vermorken JB, Peeters M, Dragan T, Van de Heyning P, De Bodt M, Van Nuffelen G
Year : 2019
Journal : Head Neck

68Ga-PSMA PET/CT-based metastasis-directed radiotherapy for oligometastatic prostate cancer recurrence after radical prostatectomy.

Authors : Artigas C, Flamen P, Charlier F, Levillain H, Wimana Z, Diamand R, Albisinni S, Gil T, Velthoven Rv, Peltier A, Gestel DV, Roumeguere T, Otte FX
Year : 2019
Journal : World J Urol

Low-Dose vs. High-Dose Cisplatin: Lessons Learned From 59 Chemoradiotherapy Trials in Head and Neck Cancer.

Authors : Szturz P, Wouters K, Kiyota N, Tahara M, Prabhash K, Noronha V, Adelstein D, Van Gestel D, Vermorken JB
Year : 2019
Journal : Front Oncol
Volume : 9
Pages : 86

Ossifying Fibromyxoid Tumor with Spinal Cord Compression and Epiduritis.

Authors : De Wandeler T, Van Gestel D, Jissendi Tchofo P
Year : 2019
Journal : J Belg Soc Radiol
Volume : 103
Pages : 18

Prophylactic cranial irradiation in stage IV small cell lung cancer: Selection of patients amongst European IASLC and ESTRO experts.

Authors : Putora PM, Glatzer M, Belderbos J, Besse B, Blackhall F, Califano R, Cappuzzo F, de Marinis F, Dziadziuszko R, Felip E, Faivre-Finn C, Früh M, Garrido P, Le Pechoux C, McDonald F, Nestle U, Novello S, OBrien M, Paz Ares L, Peeters S, Pöttgen C, Ramella S, Reck M, Slotman B, Troost EGC, Van Houtte P, Westeel V, Widder J, Mornex F, De Ruysscher D
Year : 2019
Journal : Radiother Oncol
Volume : 133
Pages : 163-166

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