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Radiotherapy remains one of the 3 pillars of treatment for patients affected by cancer. Half of all patients will undergo radiotherapy at one time or another. Radiotherapy may be used to treat cancer, improve quality of life and even to alleviate certain types of pain.

Radiotherapy uses the properties of ionizing radiation. Recent technological advances and a better understanding of the interaction between radiation and tumours has led to increasingly more effective equipment, in terms of both medical imaging (CT scan, MRI and PET scan) and radiotherapy.

Research projects


Project 1

CHEckpoint inhibition in combination with an immunoboost of External body Radiotherapy in Solid tumors: CHEERS-trial

Project 2

PEACE V: A randomized phase II trial for the Salvage Treatment of OligoRecurrent nodal prostate cancer Metastases (STORM)

Project 3

Phase IIIb randomized trial comparing irradiation plus long term adjuvant androgen deprivation with GnRH antagonist versus GnRH agonist plus flare protection in patients with very high risk localized or locally advanced prostate cancer. A joint study of the EORTC ROG and GUCG PEGASUS

Project 4

Radiation versus observation following surgical resection of atypical meningioma: a randomized controlled trial (The ROAM trial) EORTC protocol 1308-ROG-BTG
  • Project leader : Philippe Martinive
  • Funding : EORTC Cancer Research Fund / National Health System (UK)
  • Collaboration : EORTC


Project 5

A phase III trial of marizomib in combination with standard temozolomide-based radiochemotherapy versus standard temozolomide-based radiochemotherapy alone in patients with newly diagnosed glioblastoma
  • Project leader : Prof. Lefranc (Erasme) – Philippe Martinive (IJB)
  • Funding : EORTC Cancer Research Fund
  • Collaboration : EORTC

Projet 6

A prospective randomized phase 2 study of dose and volume de-escalation in prophylactic nodal irradiation of contralateral neck by sentinel lymph nodes mapping in unilaterally node positive head and neck squamous cell carcinomas


Head of Department
Prof Dirk Van Gestel : ENT tumours, skin tumours, non-malignant tumours, sarcomas, breast tumours.

Senior Registrars
Dr Sylvie Beauvois : ENT tumours
Prof. Philippe Martinive : neurological and pediatric tumors
Prof. Luigi Moretti : digestive and thoracic tumours
Dr Catherine Philippson : breast tumours, curietherapy
Dr Martine Roelandts : thoracic tumours, lymphomas, skin tumours
Prof. Honorary Paul Van Houtte : thoracic and non-malignant tumours, curietherapy

The Team
Dr Adèle Baize : gynaecological tumours and curietherapy
Dr Alex De Caluwé : breast tumours, gynaecological tumours, curietherapy
Dr Antoine Desmet : breast, skin tumors and curietherapy
Dr Tatiana Dragan : ENT tumours, sarcomas (tumours of the central nervous system)
Dr François-Xavier Otte : digestive tumours, urological tumours
Dr Robbe Van den Begin : oligometastatic, pelvic and digestive tumors

Mrs Carine Top
Mrs Carine Vandevelde

 Scientific publications

Paraganglioma of the head and neck region, treated with radiation therapy, a Rare Cancer Network study.

Authors : Lassen-Ramshad Y, Ozyar E, Alanyali S, Poortmans P, Van Houtte P, Sohawon S, Esassolak M, Krengli M, Villa S, Miller R, Demiroz C, Akyurek S, Aggerholm-Pedersen N, Thariat J
Year : 2019
Journal : Head Neck

Immune checkpoint blockade for organ transplant patients with advanced cancer: how far can we go?

Authors : De Bruyn P, Van Gestel D, Ost P, Kruse V, Brochez L, Van Vlierberghe H, Devresse A, Del Marmol V, Le Moine A, Aspeslagh S
Year : 2019
Journal : Curr Opin Oncol

Pelvic salvage (SBRT) radiotherapy based on <sup>68</sup>Ga-PSMA PET/CT: About a case.

Authors : Slaoui A, Desmet A, Regragui S, Mesfioui A, Ameur A, Peltier A
Year : 2019
Journal : Urol Case Rep
Volume : 23
Pages : 95-96

3D Monte Carlo dosimetry of intraoperative electron radiation therapy (IOERT).

Authors : Alhamada H, Simon S, Philippson C, Vandekerkhove C, Jourani Y, Pauly N, VanGestel D, Reynaert N
Year : 2019
Journal : Phys Med
Volume : 57
Pages : 207-214

Sterotactic body radiotherapy (sbrt) and oligometastatic bladder cancer : about a case and review of the literature

Authors : Mane M, Benkhaled S, Van Gestel D, Otte FX
Year : 2019
Journal : ejpmr
Volume : 6(1)
Pages : 78-83

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