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 Wetenschapelijke artikelen

Predicting Anthracycline Benefit: TOP2A and CEP17-Not Only but Also.

Auteurs : Bartlett JM, McConkey CC, Munro AF, Desmedt C, Dunn JA, Larsimont D, O Malley FP, Cameron DA, Earl HM, Poole CJ, Shepherd LE, Cardoso F, Jensen MB, Caldas C, Twelves CJ, Rea DW, Ejlertsen B, Di Leo A, Pritchard KI
Jaar : 2015
Journal : J. Clin. Oncol.
Volume : 33(15)
Pagina's : 1680-7

Evolving paradigms in multifocal breast cancer.

Auteurs : Salgado R, Aftimos P, Sotiriou C, Desmedt C
Jaar : 2015
Journal : Semin. Cancer Biol.
Volume : 31C
Pagina's : 111-118

Informed consent, biobank research, and locality: perceptions of breast cancer patients in three European countries.

Auteurs : Petersen I, Desmedt C, Harris A, Buffa F, Kollek R
Jaar : 2014
Journal : J Empir Res Hum Res Ethics
Volume : 9(3)
Pagina's : 48-55

Transfer of clinically relevant gene expression signatures in breast cancer: from Affymetrix microarray to Illumina RNA-Sequencing technology.

Auteurs : Fumagalli D, Blanchet-Cohen A, Brown D, Desmedt C, Gacquer D, Michiels S, Rothé F, Majjaj S, Salgado R, Larsimont D, Ignatiadis M, Maetens M, Piccart-Gebhart M, Detours V, Sotiriou C, Haibe-Kains B
Jaar : 2014
Journal : BMC Genomics
Volume : 15(1)
Pagina's : 1008

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

Auteurs : Tubio JM, Li Y, Ju YS, Martincorena I, Cooke SL, Tojo M, Gundem G, Pipinikas CP, Zamora J, Raine K, Menzies A, Roman-Garcia P, Fullam A, Gerstung M, Shlien A, Tarpey PS, Papaemmanuil E, Knappskog S, Van Loo P, Ramakrishna M, Davies HR, Wedge DC, Teague JW, Butler AP, Nik-Zainal S, Alexandrov L, Behjati S, Yates LR, Bolli N, Mudie L, Hardy C, Martin S, McLaren S, + collaborators (among others :, Larsimont D, Desmedt C, Sotiriou C, Campbell PJ
Jaar : 2014
Journal : Science
Volume : 345(6196)
Pagina's : 1251343

Biology of breast cancer during pregnancy using genomic profiling.

Auteurs : Azim HA, Brohée S, Peccatori FA, Desmedt C, Loi S, Lambrechts D, Dell orto P, Majjaj S, Jose V, Rotmensz N, Ignatiadis M, Pruneri G, Piccart-Gebhart M, Viale G, Sotiriou C
Jaar : 2014
Journal : Endocr Relat Cancer
Volume : 21
Pagina's : 545-54

Impact of tumor sequencing on the use of anticancer drugs.

Auteurs : Thomas F, Desmedt C, Aftimos P, Awada A
Jaar : 2014
Journal : Curr Opin Oncol
Volume : 26(3)
Pagina's : 347-56

Tumor infiltrating lymphocytes is prognostic and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trial.

Auteurs : Loi S, Michiels S, Salgado R, Sirtaine N, Jose V, Fumagalli D, Kellokumpu-Lehtinen PL, Bono P, Kataja V, Desmedt C, Piccart-Gebhart M, Loibl S, Denkert C, Smyth MJ, Joensuu H, Sotiriou C
Jaar : 2014
Journal : Ann Oncol
Volume : 25(8)
Pagina's : 1544-50

Infrared imaging in breast cancer: automated tissue component recognition and spectral characterization of breast cancer cells as well as the tumor microenvironment.

Auteurs : Benard A, Desmedt C, Smolina M, Szternfeld P, Verdonck M, Rouas G, Kheddoumi N, Rothé F, Larsimont D, Sotiriou C, Goormaghtigh E
Jaar : 2014
Journal : Analyst
Volume : 139(5)
Pagina's : 1044-56

TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers.

Auteurs : Bottai G, Lehmann-Che J, Kéri G, Orfi L, Iwamoto T, Desmedt C, Bianchini G, Turner NC, de Thè H, André F, Sotiriou C, Hortobagyi GN, Di Leo A, Pusztai L, Santarpia L
Jaar : 2014
Journal : Mol oncol
Volume : 8(3)
Pagina's : 508-19

Genomic grade adds prognostic value in invasive lobular carcinoma.

Auteurs : Metzger-Filho O, Michiels S, Bertucci F, Catteau A, Salgado R, Galant C, Fumagalli D, Singhal SK, Desmedt C, Ignatiadis M, Haussy S, Finetti P, Birnbaum D, Saini KS, Berlière M, Veys I, de Azambuja E, Bozovic I, Peyro-Saint-Paul H, Larsimont D, Piccart-Gebhart M, Sotiriou C
Jaar : 2013
Journal : Ann Oncol
Volume : 24
Pagina's : 377-384

Genomic grade adds prognostic value in invasive lobular carcinoma.

Auteurs : Metzger-Filho O, Michiels S, Bertucci F, Catteau A, Salgado R, Galant C, Fumagalli D, Singhal SK, Desmedt C, Ignatiadis M, Sandy H, Finetti P, Birnbaum D, Saini KS, Berlière M, Veys I, de Azambuja E, Bozovic I, Peyro-Saint-Paul H, Larsimont D, Piccart-Gebhart M, Sotiriou C
Jaar : 2013
Journal : Ann Oncol
Volume : 24(2)
Pagina's : 377-84

TOP2A protein by quantitative immunofluorescence as a predictor of response to epirubicin in the neoadjuvant treatment of breast cancer.

Auteurs : Moretti E, Desmedt C, Biagioni C, Regan MM, Oakman C, Larsimont D, Galardi F, Piccart-Gebhart M, Sotiriou C, Rimm DL, Di Leo A
Jaar : 2013
Journal : Future Oncol
Volume : 9(10)
Pagina's : 1477-87

CD4+ follicular helper T cell infiltration predicts breast cancer survival.

Auteurs : Gu-Trantien C, Loi S, Garaud S, Equeter C, Libin M, de Wind A, Ravoet M, Le Buanec H, Sibille C, Manfouo-Foutsop G, Veys I, Haibe-Kains B, Singhal SK, Michiels S, Rothé F, Salgado R, Duvillier H, Ignatiadis M, Desmedt C, Bron D, Larsimont D, Piccart-Gebhart M, Sotiriou C, Willard-Gallo K
Jaar : 2013
Journal : J Clin Invest
Volume : 123(7)
Pagina's : 2873-92

Association between SPARC mRNA Expression, Prognosis and Response to Neoadjuvant Chemotherapy in Early Breast Cancer: A Pooled in-silico Analysis.

Auteurs : Azim HA, Singhal S, Ignatiadis M, Desmedt C, Fumagalli D, Veys I, Larsimont D, Piccart-Gebhart M, Michiels S, Sotiriou C
Jaar : 2013
Journal : PLoS One
Volume : 8(4)
Pagina's : e62451

Change in the microenvironment of breast cancer studied by FTIR imaging.

Auteurs : Kumar S, Desmedt C, Larsimont D, Sotiriou C, Goormaghtigh E
Jaar : 2013
Journal : Analyst
Volume : 138(14)
Pagina's : 4058-65

Breast cancer and melanoma cell line identification by FTIR imaging after formalin-fixation and paraffin-embedding.

Auteurs : Verdonck M, Wald N, Janssis J, Yan P, Meyer C, Legat A, Speiser DE, Desmedt C, Larsimont D, Sotiriou C, Goormaghtigh E
Jaar : 2013
Journal : Analyst
Volume : 138(14)
Pagina's : 4083-91

Characterization and clinical evaluation of CD10+ stroma cells in the breast cancer microenvironment.

Auteurs : Desmedt C, Majjaj S, Kheddoumi N, Singhal SK, Haibe-Kains B, El Ouriaghli F, Chaboteaux C, Michiels S, Lallemand F, Journe F, Duvillier H, Loi S, Quackenbush J, Dekoninck S, Blanpain C, Lagneaux L, Houhou N, Delorenzi M, Larsimont D, Piccart-Gebhart M, Sotiriou C
Jaar : 2012
Journal : Clin Cancer Res
Volume : 18(4)
Pagina's : 1004-14

A three-gene model to robustly identify breast cancer molecular subtypes.

Auteurs : Haibe-Kains B, Desmedt C, Loi S, Culhane AC, Bontempi G, Quackenbush J, Sotiriou C
Jaar : 2012
Journal : J. Natl. Cancer Inst.
Volume : 104(4)
Pagina's : 311-25

The landscape of cancer genes and mutational processes in breast cancer.

Auteurs : Stephens PJ, Tarpey PS, Davies H, Van Loo P, Greenman C, Wedge DC, Nik-Zainal S, Martin S, Varela I, Bignell GR, Yates LR, Papaemmanuil E, Beare D, Butler A, Cheverton A, Gamble J, Hinton J, Jia M, Jayakumar A, Jones D, Latimer C, Lau KW, McLaren S, McBride DJ, Menzies A, Mudie L, Raine K, Rad R, Chapman MS, Teague J, Easton D, Langerød A, Lee MT, Shen CY, Tee BT, Huimin BW, Broeks A, Vargas AC, Turashvili G, Martens J, Fatima A, Miron P, Chin SF, Thomas G, Boyault S, Mariani O, Lakhani SR, van de Vijver M, + collaborators (among others :, Desmedt C, Sotiriou C, Stratton MR
Jaar : 2012
Journal : Nature
Volume : 486(7403)
Pagina's : 400-4