Articles scientifiques

PIK3CA genotype and a PIK3CA mutation-related gene signature and response to everolimus and letrozole in estrogen receptor positive breast cancer.

Auteurs : Loi S, Michiels S, Baselga J, Bartlett JM, Singhal SK, Sabine VS, Sims AH, Sahmoud T, Dixon JM, Piccart-Gebhart M, Sotiriou C
Année : 2013
Journal : PLoS One
Volume : 8(1)
Pages : e53292

Circulating miR-150 and miR-342 in plasma are novel potential biomarkers for acute myeloid leukemia.

Auteurs : Fayyad-Kazan H, Bitar N, Najar M, Lewalle P, Fayyad-Kazan M, Badran R, Hamade E, Daher A, Hussein N, Eldirani R, Berri F, Vanhamme L, Burny A, Martiat P, Rouas R, Badran B
Année : 2013
Journal : J Transl Med
Volume : 11(1)
Pages : 31

Prognostic and Predictive Value of Tumor-Infiltrating Lymphocytes in a Phase III Randomized Adjuvant Breast Cancer Trial in Node-Positive Breast Cancer Comparing the Addition of Docetaxel to Doxorubicin With Doxorubicin-Based Chemotherapy: BIG 02-98.

Auteurs : Loi S, Sirtaine N, Piette F, Salgado R, Viale G, Van Eenoo F, Rouas G, Francis P, Crown JP, Hitre E, de Azambuja E, Quinaux E, Di Leo A, Michiels S, Piccart-Gebhart M, Sotiriou C
Année : 2013
Journal : J. Clin. Oncol.
Volume : 31(7)
Pages : 860-7

Relevance of a systematic geriatric screening and assessment in older patients with cancer: results of a prospective multicentric study.

Auteurs : Kenis C, Bron D, Libert Y, Decoster L, Van Puyvelde K, Scalliet P, Cornette P, Pepersack T, Luce S, Langenaeken C, Rasschaert M, Allepaerts S, Van Rijswijk R, Milisen K, Flamaing J, Lobelle JP, Wildiers H
Année : 2013
Journal : Ann Oncol
Volume : 24(5)
Pages : 1306-12

Erratum to: Immune-Related Antigens, Surface Molecules and Regulatory Factors in Human-Derived Mesenchymal Stromal Cells: The Expression and Impact of Inflammatory Priming.

Auteurs : Najar M, Raicevic G, Fayyad-Kazan H, De Bruyn C, Bron D, Toungouz M, Lagneaux L
Année : 2012
Journal : Stem Cell Rev
Volume : 8(4)
Pages : 1286

A common language in neoadjuvant breast cancer clinical trials: proposals for standard definitions and endpoints.

Auteurs : Fumagalli D, Bedard PL, Nahleh Z, Michiels S, Sotiriou C, Loi S, Sparano JA, Ellis M, Hylton N, Zujewski JA, Hudis C, Esserman L, Piccart-Gebhart M
Année : 2012
Journal : Lancet Oncol
Volume : 13(6)
Pages : e240-8

MicroRNA profile of circulating CD4-positive regulatory T cells in human adults and impact of differentially expressed microRNAs on expression of two genes essential to their function.

Auteurs : Fayyad-Kazan H, Rouas R, Fayyad-Kazan M, Badran R, El Zein N, Lewalle P, Najar M, Hamade E, Jebbawi F, Merimi M, Romero P, Burny A, Badran B, Martiat P
Année : 2012
Journal : J. Biol. Chem.
Volume : 287(13)
Pages : 9910-22

Elucidating prognosis and biology of breast cancer arising in young women using gene expression profiling.

Auteurs : Azim HA, Michiels S, Bedard PL, Singhal SK, Criscitiello C, Ignatiadis M, Haibe-Kains B, Piccart-Gebhart M, Sotiriou C, Loi S
Année : 2012
Journal : Clin Cancer Res
Volume : 18(5)
Pages : 1341-51

Characterization and clinical evaluation of CD10+ stroma cells in the breast cancer microenvironment.

Auteurs : Desmedt C, Majjaj S, Kheddoumi N, Singhal SK, Haibe-Kains B, El Ouriaghli F, Chaboteaux C, Michiels S, Lallemand F, Journe F, Duvillier H, Loi S, Quackenbush J, Dekoninck S, Blanpain C, Lagneaux L, Houhou N, Delorenzi M, Larsimont D, Piccart-Gebhart M, Sotiriou C
Année : 2012
Journal : Clin Cancer Res
Volume : 18(4)
Pages : 1004-14

Gene modules and response to neoadjuvant chemotherapy in breast cancer subtypes: a pooled analysis.

Auteurs : Ignatiadis M, Singhal SK, Desmedt C, Haibe-Kains B, Criscitiello C, Andre F, Loi S, Piccart-Gebhart M, Michiels S, Sotiriou C
Année : 2012
Journal : J. Clin. Oncol.
Volume : 30(16)
Pages : 1996-2004

AMD3100 disrupts the cross-talk between chronic lymphocytic leukemia cells and a mesenchymal stromal or nurse-like cell -based microenvironment: preclinical evidence for its association with chronic lymphocytic leukemia treatments.

Auteurs : Stamatopoulos B, Meuleman N, De Bruyn C, Pieters K, Mineur P, Le Roy C, Saint-Georges S, Varin-Blank N, Cymbalista F, Bron D, Lagneaux L
Année : 2012
Journal : Haematologica
Volume : 97(4)
Pages : 608-615

MYC+ diffuse large B-cell lymphoma is not salvaged by classical R-ICE or R-DHAP followed by BEAM plus autologous stem cell transplantation.

Auteurs : Cuccuini W, Briere J, Mounier N, Voelker HU, Rosenwald A, Sundstrom C, Cogliatti S, Hirchaud E, Ysebaert L, Bron D, Soulier J, Gaulard P, Houlgatte R, Gisselbrecht C, Thieblemont C
Année : 2012
Journal : Blood
Volume : 119(20)
Pages : 4619-24

Inflammation and Toll-like receptor ligation differentially affect the osteogenic potential of human mesenchymal stromal cells depending on their tissue origin.

Auteurs : Raicevic G, Najar M, Pieters K, De Bruyn C, Meuleman N, Bron D, Toungouz M, Lagneaux L
Année : 2012
Journal : Tissue Eng Part A
Volume : 18(13-14)
Pages : 1410-8

Characterization and functionality of the CD200-CD200R system during mesenchymal stromal cell interactions with T-lymphocytes.

Auteurs : Najar M, Raicevic G, Jebbawi F, De Bruyn C, Meuleman N, Bron D, Toungouz M, Lagneaux L
Année : 2012
Journal : Immunol. Lett.
Volume : 146(1-2)
Pages : 50-6

Immune-Related Antigens, Surface Molecules and Regulatory Factors in Human-Derived Mesenchymal Stromal Cells: The Expression and Impact of Inflammatory Priming.

Auteurs : Najar M, Raicevic G, Kazan HF, De Bruyn C, Bron D, Toungouz M, Lagneaux L
Année : 2012
Journal : Stem Cell Rev
Volume : 8(4)
Pages : 1188-98

Therapeutic drug monitoring of posaconazole in patients with acute myeloid leukemia or myelodysplasic syndrome: a bicentric study.

Auteurs : Vaes M, Hites M, Cotton F, Bourguignon AM, Csergo M, Rasson C, Ameye L, Bron D, Jacobs F, Aoun M
Année : 2012
Journal : Antimicrob. Agents Chemother.
Volume : 56(12))
Pages : 6298-303

Mastocytosis: revisited with new cytogenetic data.

Auteurs : Vaes M, Vereecken P, de Wind R, Andry G, Li R, Bron D
Année : 2012
Journal : Rev Med Brux
Volume : 33(1)
Pages : 12-21

Safety and Efficacy of Radioimmunotherapy with 90Yttrium-rituximab in Patients with Relapsed CD20+ B cell Lymphoma: A Feasibility Study

Auteurs : Vaes M, Bron D, Vugts DJ, Paesmans M, Meuleman N, Ghanem G, Vanderlinden B, Thielemans K, van Dongen GA, Flamen P, Muylle K
Année : 2012
Journal : J Cancer Sci Ther
Volume : 4(12)
Pages : 394-400

Molecular subclasses of breast cancer: how do we define them? The IMPAKT 2012 Working Group Statement.

Auteurs : Guiu S, Michiels S, André F, Cortes J, Denkert C, Di Leo A, Hennessy BT, Sorlie T, Sotiriou C, Turner N, van de Vijver M, Viale G, Loi S, Reis-Filho JS
Année : 2012
Journal : Ann Oncol
Volume : 23
Pages : 2997-3006

Association between the nuclear to cytoplasmic ratio of p27 and the efficacy of adjuvant polychemotherapy in early breast cancer.

Auteurs : Andre F, Conforti R, Moeder CB, Mauguen A, Arnedos M, Berrada N, Delaloge S, Tomasic G, Spielmann M, Esteva FJ, Rimm DL, Michiels S
Année : 2012
Journal : Ann Oncol
Volume : 23
Pages : 2059-2064