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 Articles scientifiques

Lesion-based detection of early chemosensitivity using serial static FDG PET/CT in metastatic colorectal cancer.

Auteurs : Buvat I, Necib H, Garcia C, Wagner A, Vanderlinden B, Emonts P, Hendlisz A, Flamen P
Année : 2012
Journal : Eur J Nucl Med Mol Imaging
Volume : 39(10)
Pages : 1628-34

Characterization and clinical evaluation of CD10+ stroma cells in the breast cancer microenvironment.

Auteurs : Desmedt C, Majjaj S, Kheddoumi N, Singhal SK, Haibe-Kains B, El Ouriaghli F, Chaboteaux C, Michiels S, Lallemand F, Journe F, Duvillier H, Loi S, Quackenbush J, Dekoninck S, Blanpain C, Lagneaux L, Houhou N, Delorenzi M, Larsimont D, Piccart-Gebhart M, Sotiriou C
Année : 2012
Journal : Clin Cancer Res
Volume : 18(4)
Pages : 1004-14

A three-gene model to robustly identify breast cancer molecular subtypes.

Auteurs : Haibe-Kains B, Desmedt C, Loi S, Culhane AC, Bontempi G, Quackenbush J, Sotiriou C
Année : 2012
Journal : J. Natl. Cancer Inst.
Volume : 104(4)
Pages : 311-25

The landscape of cancer genes and mutational processes in breast cancer.

Auteurs : Stephens PJ, Tarpey PS, Davies H, Van Loo P, Greenman C, Wedge DC, Nik-Zainal S, Martin S, Varela I, Bignell GR, Yates LR, Papaemmanuil E, Beare D, Butler A, Cheverton A, Gamble J, Hinton J, Jia M, Jayakumar A, Jones D, Latimer C, Lau KW, McLaren S, McBride DJ, Menzies A, Mudie L, Raine K, Rad R, Chapman MS, Teague J, Easton D, Langerød A, Lee MT, Shen CY, Tee BT, Huimin BW, Broeks A, Vargas AC, Turashvili G, Martens J, Fatima A, Miron P, Chin SF, Thomas G, Boyault S, Mariani O, Lakhani SR, van de Vijver M, + collaborators (among others :, Desmedt C, Sotiriou C, Stratton MR
Année : 2012
Journal : Nature
Volume : 486(7403)
Pages : 400-4

Gene modules and response to neoadjuvant chemotherapy in breast cancer subtypes: a pooled analysis.

Auteurs : Ignatiadis M, Singhal SK, Desmedt C, Haibe-Kains B, Criscitiello C, Andre F, Loi S, Piccart-Gebhart M, Michiels S, Sotiriou C
Année : 2012
Journal : J. Clin. Oncol.
Volume : 30(16)
Pages : 1996-2004

Molecular biology in breast cancer: Should molecular classifiers be assessed by conventional tools or by gene expression arrays?

Auteurs : Fumagalli D, Andre F, Piccart-Gebhart M, Sotiriou C, Desmedt C
Année : 2012
Journal : Crit Rev Oncol Hematol
Volume : 84 supl 1
Pages : e58-69

Next-generation sequencing in breast cancer: first take home messages.

Auteurs : Desmedt C, Voet T, Sotiriou C, Campbell PJ
Année : 2012
Journal : Curr Opin Oncol
Volume : 24(6)
Pages : 597-604

Treatment Options in Anthracycline and/or Taxane Pretreated Patients with Metastatic Breast Cancer.

Auteurs : Pugliano L, de Azambuja E
Année : 2012
Journal : Onkologie
Volume : 35(9)
Pages : 476-8

Bevacizumab and Breast Cancer: A Meta-Analysis of First-Line Phase III Studies and a Critical Reappraisal of Available Evidence.

Auteurs : Rossari JR, Metzger-Filho O, Paesmans M, Saini KS, Gennari A, de Azambuja E, Piccart-Gebhart M
Année : 2012
Journal : J Oncol
Volume : 2012
Pages : 417673

Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial.

Auteurs : Baselga J, Bradbury I, Eidtmann H, Di Cosimo S, de Azambuja E, Aura C, Gómez H, Dinh P, Fauria K, van Dooren V, Aktan G, Goldhirsch A, Chang TW, Horváth Z, Coccia-Portugal M, Domont J, Tseng LM, Kunz G, Sohn JH, Semiglazov V, Lerzo G, Palacova M, Probachai V, Pusztai L, Untch M, Gelber Rd, Piccart-Gebhart M
Année : 2012
Journal : Lancet
Volume : 379(9816)
Pages : 633-40

Pregnancy occurring during or following adjuvant trastuzumab in patients enrolled in the HERA trial (BIG 01-01).

Auteurs : Azim HA, Metzger-Filho O, de Azambuja E, Loibl S, Focant F, Gresko E, Arfi M, Piccart-Gebhart M
Année : 2012
Journal : Breast Cancer Res. Treat.
Volume : 133(1)
Pages : 387-91

Dissecting the heterogeneity of triple-negative breast cancer.

Auteurs : Metzger-Filho O, Tutt A, de Azambuja E, Saini KS, Viale G, Loi S, Bradbury I, Bliss JM, Azim HA, Ellis P, Di Leo A, Baselga J, Sotiriou C, Piccart-Gebhart M
Année : 2012
Journal : J. Clin. Oncol.
Volume : 30(15)
Pages : 1879-87

Targeted therapies in breast cancer: are heart and vessels also being targeted?

Auteurs : Criscitiello C, Metzger-Filho O, Saini KS, de Castro G, Diaz M, La Gerche A, de Azambuja E, Piccart-Gebhart M
Année : 2012
Journal : Breast Cancer Res
Volume : 14(3)
Pages : 209

Dual human epidermal growth factor receptor 2 blockade: another step forward in treating patients with human epidermal growth factor receptor 2-positive breast cancer.

Auteurs : Zardavas D, Bozovic-Spasojevic I, de Azambuja E
Année : 2012
Journal : Curr Opin Oncol
Volume : 24(6)
Pages : 612-22

MYC+ diffuse large B-cell lymphoma is not salvaged by classical R-ICE or R-DHAP followed by BEAM plus autologous stem cell transplantation.

Auteurs : Cuccuini W, Briere J, Mounier N, Voelker HU, Rosenwald A, Sundstrom C, Cogliatti S, Hirchaud E, Ysebaert L, Bron D, Soulier J, Gaulard P, Houlgatte R, Gisselbrecht C, Thieblemont C
Année : 2012
Journal : Blood
Volume : 119(20)
Pages : 4619-24

Inflammation and Toll-like receptor ligation differentially affect the osteogenic potential of human mesenchymal stromal cells depending on their tissue origin.

Auteurs : Raicevic G, Najar M, Pieters K, De Bruyn C, Meuleman N, Bron D, Toungouz M, Lagneaux L
Année : 2012
Journal : Tissue Eng Part A
Volume : 18(13-14)
Pages : 1410-8

Characterization and functionality of the CD200-CD200R system during mesenchymal stromal cell interactions with T-lymphocytes.

Auteurs : Najar M, Raicevic G, Jebbawi F, De Bruyn C, Meuleman N, Bron D, Toungouz M, Lagneaux L
Année : 2012
Journal : Immunol. Lett.
Volume : 146(1-2)
Pages : 50-6

Immune-Related Antigens, Surface Molecules and Regulatory Factors in Human-Derived Mesenchymal Stromal Cells: The Expression and Impact of Inflammatory Priming.

Auteurs : Najar M, Raicevic G, Kazan HF, De Bruyn C, Bron D, Toungouz M, Lagneaux L
Année : 2012
Journal : Stem Cell Rev
Volume : 8(4)
Pages : 1188-98

Final results and pharmacoeconomic analysis of a trial comparing two neoadjuvant chemotherapy (CT) regimens followed by surgery in patients with resectable non-small cell lung cancer (NSCLC): A phase II randomised study by the European Lung Cancer Wo

Auteurs : Berghmans T, Lafitte JJ, Giner V, Berchier MC, Scherpereel A, Lewin D, Paesmans M, Meert AP, Bosschaerts T, Leclercq N, Sculier JP
Année : 2012
Journal : Lung Cancer
Volume : 77(3)
Pages : 605-610

Euthanasia: from ethical debate to clinical reality.

Auteurs : Berghmans T, Lossignol D
Année : 2012
Journal : Eur. Respir. J.
Volume : 40(4)
Pages : 804-5