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 Articles scientifiques

Targeted therapy for breast cancer in older patients.

Auteurs : Pondé N, Wildiers H, Awada A, de Azambuja E, Deliens C, Lago LD
Année : 2020
Journal : J Geriatr Oncol
Volume : 11
Pages : 380-388

Computed tomography-based analyses of baseline body composition parameters and changes in breast cancer patients under treatment with CDK 4/6 inhibitors.

Auteurs : Franzoi MA, Vandeputte C, Eiger D, Caparica R, Brandão M, de Angelis C, Hendlisz A, Awada A, Piccart M, de Azambuja E
Année : 2020
Journal : Breast Cancer Res Treat
Volume : 181
Pages : 199-209

Prognostic and Predictive Impact of Beta-2 Adrenergic Receptor Expression in HER2-Positive Breast Cancer.

Auteurs : Caparica R, Richard F, Brandão M, Awada A, Sotiriou C, de Azambuja E
Année : 2020
Journal : Clin Breast Cancer
Volume : 20
Pages : 262-273.e7

Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-label, phase 2 basket trial.

Auteurs : Trigo J, Subbiah V, Besse B, Moreno V, López R, Sala MA, Peters S, Ponce S, Fernández C, Alfaro V, Gómez J, Kahatt C, Zeaiter A, Zaman K, Boni V, Arrondeau J, Martínez M, Delord JP, Awada A, Kristeleit R, Olmedo ME, Wannesson L, Valdivia J, Rubio MJ, Anton A, Sarantopoulos J, Chawla SP, Mosquera-Martinez J, DArcangelo M, Santoro A, Villalobos VM, Sands J, Paz-Ares L
Année : 2020
Journal : Lancet Oncol
Volume : 21
Pages : 645-654

Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance Short Title: Sensitivity Prediction to MAPK Inhibitors in Melanoma.

Auteurs : Krayem M, Aftimos P, Najem A, van den Hooven T, van den Berg A, Hovestad-Bijl L, de Wijn R, Hilhorst R, Ruijtenbeek R, Sabbah M, Kerger J, Awada A, Journe F, Ghanem GE
Année : 2020
Journal : Cancers (Basel)
Volume : 12

On-Target Pharmacodynamic Activity of the PI3K Inhibitor Copanlisib in Paired Biopsies from Patients with Malignant Lymphoma and Advanced Solid Tumors.

Auteurs : Morschhauser F, Machiels JP, Salles G, Rottey S, Rule SAJ, Cunningham D, Peyrade F, Fruchart C, Arkenau HT, Genvresse I, Liu L, Köchert K, Shen K, Kneip C, Peña CE, Grevel J, Zhang J, Cisternas G, Reschke S, Granvil C, Awada A
Année : 2020
Journal : Mol Cancer Ther
Volume : 19
Pages : 468-478

Palbociclib safety and efficacy beyond Ribociclib-induced liver toxicity in metastatic hormone-receptors positive breast cancer patient.

Auteurs : Farhat F, Tarabaih M, Kanj A, Aoun M, Kattan J, Assi T, Awada A
Année : 2020
Journal : Anticancer Drugs
Volume : 31
Pages : 85-89

Feasibility and clinical impact of routine molecular testing of gastrointestinal cancers at a tertiary centre with a multi-gene, tumor-agnostic, next generation sequencing panel.

Auteurs : Bregni G, Sticca T, Camera S, Akin Telli T, Craciun L, Trevisi E, Pretta A, Kehagias P, Leduc S, Senti C, Deleporte A, Vandeputte C, Saad ED, Kerger J, Gil T, Piccart-Gebhart M, Awada A, Demetter P, Larsimont D, Hendlisz A, Aftimos P, Sclafani F
Année : 2020
Journal : 0
Pages : 1-9

Metronomic chemotherapy for patients with metastatic breast cancer: Review of effectiveness and potential use during pandemics.

Auteurs : Fares JE, El Tomb P, Khalil LE, Atwani RW, Moukadem HA, Awada A, El Saghir NS
Année : 2020
Journal : Cancer Treat Rev
Volume : 89
Pages : 102066

Clinical implications of body mass index in metastatic breast cancer patients treated with abemaciclib and endocrine therapy.

Auteurs : Franzoi MA, Eiger D, Ameye L, Ponde N, Caparica R, de Angelis C, Brandão M, Desmedt C, Di Cosimo S, Kotecki N, Lambertini M, Awada A, Piccart M, de Azambuja E
Année : 2020
Journal : J Natl Cancer Inst

Targeting molecular subtypes in solid cancers: successes and failures.

Auteurs : Assi R, Kotecki N, Awada A
Année : 2020
Journal : Curr Opin Oncol
Volume : 32
Pages : 488-493

A Phase 2 Study of Abemaciclib in Patients with Brain Metastases Secondary to Hormone Receptor Positive Breast Cancer.

Auteurs : Tolaney SM, Sahebjam S, Le Rhun E, Bachelot T, Kabos P, Awada A, Yardley D, Chan A, Conte P, Diéras V, Lin NU, Bear M, Chapman SC, Yang Z, Chen Y, Anders CK
Année : 2020
Journal : Clin Cancer Res

[Tolerablity of everolimus in clinical practice: a retrospective study].

Auteurs : Afani L, Belbaraka R, Awada A
Année : 2020
Journal : Pan Afr Med J
Volume : 36
Pages : 26

Bintrafusp alfa, a bifunctional fusion protein targeting TGF-ß and PD-L1, in advanced squamous cell carcinoma of the head and neck: results from a phase I cohort.

Auteurs : Cho BC, Daste A, Ravaud A, Salas S, Isambert N, McClay E, Awada A, Borel C, Ojalvo LS, Helwig C, Rolfe PA, Gulley JL, Penel N
Année : 2020
Journal : J Immunother Cancer
Volume : 8

MOMENTUM: A Phase I Trial Investigating 2 Schedules of Capecitabine With Aflibercept in Patients With Gastrointestinal and Breast Cancer.

Auteurs : Camera S, Deleporte A, Bregni G, Trevisi E, Pretta A, Telli TA, Polastro L, Gombos A, Kayumba A, Ameye L, Piccart-Gebhart M, Awada A, Sclafani F, Hendlisz A
Année : 2020
Journal : Clin Colorectal Cancer

Metastatic breast cancer and pseudocirrhosis: an unknown clinical entity.

Auteurs : Engelman D, Moreau M, Lepida A, Zaouak Y, Paesmans M, Awada A
Année : 2020
Journal : ESMO Open
Volume : 5

ESMO Clinical Research Observatory (ECRO): improving the efficiency of clinical research through rationalisation of bureaucracy.

Auteurs : Perez-Gracia JL, Awada A, Calvo E, Amaral T, Arkenau HT, Gruenwald V, Bodoky G, Lolkema MP, Di Nicola M, Penel N, Vera R, Sanmamed MF, Douillard JY
Année : 2020
Journal : ESMO Open
Volume : 5

Neutropenia management in patients receiving myelosuppressive polychemotherapy for early breast cancer in Belgium: BRONS study results.

Auteurs : Catala G, Mebis J, Jerusalem G, Verhoeven D, Awada A, Bols A, Somers L, Van Den Broeck A, Duhoux FP, Machiels JP
Année : 2020
Journal : Acta Clin Belg
Volume : 75
Pages : 128-135

A Randomized Placebo-Controlled Phase 2 Trial Evaluating Exemestane With or Without Enzalutamide in Patients With Hormone Receptor-positive Breast Cancer.

Auteurs : Krop I, Abramson VG, Colleoni M, Traina TA, Holmes FA, Garcia-Estevez L, Hart L, Awada A, Zamagni C, Morris PG, Schwartzberg LS, Chan SY, Gucalp A, Biganzoli L, Steinberg J, Sica L, Trudeau ME, Markova D, Tarazi JC, Zhu Z, OBrien T, Kelly C, Winer EP, Yardley D
Année : 2020
Journal : Clin Cancer Res

Reimagining Global Oncology Clinical Trials for the Postpandemic Era: A Call to Arms.

Auteurs : Saini KS, de Las Heras B, Plummer R, Moreno V, Romano M, de Castro J, Aftimos P, Fredriksson J, Bhattacharyya GS, Olivo MS, Schiavon G, Punie K, Garcia-Foncillas J, Rogata E, Pfeiffer R, Orbegoso C, Morrison K, Curigliano G, Chin L, Saini ML, Rekdal Ø, Anderson S, Cortes J, Leone M, Dancey J, Twelves C, Awada A
Année : 2020
Journal : JCO Glob Oncol
Volume : 6
Pages : 1357-1362