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 Articles scientifiques

CYAD-01, an autologous NKG2D-based CAR T-cell therapy, in relapsed or refractory acute myeloid leukaemia and myelodysplastic syndromes or multiple myeloma (THINK): haematological cohorts of the dose escalation segment of a phase 1 trial.

Auteurs : Sallman DA, Kerre T, Havelange V, Poiré X, Lewalle P, Wang ES, Brayer JB, Davila ML, Moors I, Machiels JP, Awada A, Alcantar-Orozco EM, Borissova R, Braun N, Dheur MS, Gilham DE, Lonez C, Lehmann FF, Flament A
Année : 2023
Journal : Lancet Haematol

Sequential administration of low dose 5-azacytidine (AZA) and donor lymphocyte infusion (DLI) for patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) in relapse after allogeneic stem cell transplantation (SCT): a prospective

Auteurs : Poiré X, Graux C, Ory A, Herman J, Baron F, Schoemans H, Lewalle P, De Becker A, Deeren D, Berneman Z, Kerre T, Zachée P, Selleslag D, Beguin Y
Année : 2022
Journal : Bone Marrow Transplant
Volume : 57
Pages : 116-118

New Perspectives in Treating Acute Myeloid Leukemia: Driving towards a Patient-Tailored Strategy.

Auteurs : Andreozzi F, Massaro F, Wittnebel S, Spilleboudt C, Lewalle P, Salaroli A
Année : 2022
Journal : Int J Mol Sci
Volume : 23

NK cells and monocytes modulate primary HTLV-1 infection.

Auteurs : Moles R, Sarkis S, Galli V, Omsland M, Artesi M, Bissa M, McKinnon K, Brown S, Hahaut V, Washington-Parks R, Welsh J, Venzon DJ, Gutowska A, Doster MN, Breed MW, Killoran KE, Kramer J, Jones J, Moniuszko M, Van den Broeke A, Pise-Masison CA, Franchini G
Année : 2022
Journal : PLoS Pathog
Volume : 18
Pages : e1010416

OncomiRs as noncoding RNAs having functions in cancer: Their role in immune suppression and clinical implications.

Auteurs : Otmani K, Rouas R, Lewalle P
Année : 2022
Journal : Front Immunol
Volume : 13
Pages : 913951

Fundamental and Applied Advances in Stem Cell Therapeutic Research.

Auteurs : Merimi M, Rahmani S, Afailal Tribak A, Bouhtit F, Fahmi H, Najar M
Année : 2022
Journal : Cells
Volume : 11

Outcomes after allogeneic hematopoietic stem cell transplantation for adults with primary mediastinal B cell lymphoma: a SFGM-TC and LYSA study.

Auteurs : Le Calvez B, Tessoullin B, Renaud L, Botella-Garcia C, Srour M, Le Gouill S, Guillerm G, Gressin R, Nguyen Quoc S, Furst S, Chauchet A, Sibon D, Lewalle P, Poiré X, Maillard N, Villate A, Loschi M, Paillassa J, Beguin Y, Dulery R, Tudesq JJ, Fayard A, Béné MC, Camus V, Chevallier P, Le Bourgeois A
Année : 2022
Journal : Acta Oncol
Volume : 61
Pages : 1332-1338

Bioscreening and pre-clinical evaluation of the impact of bioactive molecules from Ptychotis verticillata on the multilineage potential of mesenchymal stromal cells towards immune- and inflammation-mediated diseases.

Auteurs : Bouhtit F, Najar M, Rahmani S, Melki R, Najimi M, Sadki K, Boukhatem N, Twizere JC, Meuleman N, Lewalle P, Lagneaux L, Merimi M
Année : 2022
Journal : Inflamm Res
Volume : 71
Pages : 887-898

Mesenchymal Stem/Stromal Cells as a Therapeutic Tool in Cell-Based Therapy and Regenerative Medicine: An Introduction Expertise to the Topical Collection.

Auteurs : Merimi M, Fahmi H, De Kock J, Beguin C, Burny A, Moll G, Poggi A, Najar M
Année : 2022
Journal : Cells
Volume : 11

Donor-Derived Myeloid Heme Oxygenase-1 Controls the Development of Graft-Versus-Host Disease.

Auteurs : Spilleboudt C, de Wilde V, Lewalle P, Cabanne L, Leclerc M, Beckerich F, Bories D, Cardoso S, Soares MP, Vokaer B, Hougardy JM, Flamand V, Racapé J, Abramowicz M, Maury S, Le Moine A
Année : 2021
Journal : Front Immunol
Volume : 11
Pages : 579151

PCIP-seq: simultaneous sequencing of integrated viral genomes and their insertion sites with long reads.

Auteurs : Artesi M, Hahaut V, Cole B, Lambrechts L, Ashrafi F, Marçais A, Hermine O, Griebel P, Arsic N, van der Meer F, Burny A, Bron D, Bianchi E, Delvenne P, Bours V, Charlier C, Georges M, Vandekerckhove L, Van den Broeke A, Durkin K
Année : 2021
Journal : Genome Biol
Volume : 22
Pages : 97

Mesenchymal Stem/Stromal Cell Therapeutic Features: The Bridge between the Bench and the Clinic.

Auteurs : Merimi M, Lewalle P, Meuleman N, Agha DM, El-Kehdy H, Bouhtit F, Ayoub S, Burny A, Fahmi H, Lagneaux L, Najar M
Année : 2021
Journal : J Clin Med
Volume : 10

Clinical outcomes in patients with Philadelphia chromosome-positive leukemia treated with ponatinib in routine clinical practice-data from a Belgian registry.

Auteurs : Devos T, Havelange V, Theunissen K, Meers S, Benghiat FS, Gadisseur A, Vanstraelen G, Vellemans H, Bailly B, Granacher N, Lewalle P, De Becker A, Van Eygen K, Janssen M, Triffet A, Vrelust I, Deeren D, Mazure D, Bekaert J, Beck M, Selleslag D
Année : 2021
Journal : Ann Hematol
Volume : 100
Pages : 1723-1732

Apoptotic and Non-Apoptotic Modalities of Thymoquinone-Induced Lymphoma Cell Death: Highlight of the Role of Cytosolic Calcium and Necroptosis.

Auteurs : Berehab M, Rouas R, Akl H, Duvillier H, Journe F, Fayyad-Kazan H, Ghanem G, Bron D, Lewalle P, Merimi M
Année : 2021
Journal : Cancers (Basel)
Volume : 13

Transcriptional Profile of Cytokines, Regulatory Mediators and TLR in Mesenchymal Stromal Cells after Inflammatory Signaling and Cell-Passaging.

Auteurs : Merimi M, Buyl K, Daassi D, Rodrigues RM, Melki R, Lewalle P, Vanhaecke T, Fahmi H, Rogiers V, Lagneaux L, De Kock J, Najar M
Année : 2021
Journal : Int J Mol Sci
Volume : 22

The Therapeutic Potential of Mesenchymal Stromal Cells for Regenerative Medicine: Current Knowledge and Future Understandings.

Auteurs : Merimi M, El-Majzoub R, Lagneaux L, Moussa Agha D, Bouhtit F, Meuleman N, Fahmi H, Lewalle P, Fayyad-Kazan M, Najar M
Année : 2021
Journal : Front Cell Dev Biol
Volume : 9
Pages : 661532

The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape.

Auteurs : Vandermeulen C, OGrady T, Wayet J, Galvan B, Maseko S, Cherkaoui M, Desbuleux A, Coppin G, Olivet J, Ben Ameur L, Kataoka K, Ogawa S, Hermine O, Marcais A, Thiry M, Mortreux F, Calderwood MA, Van Weyenbergh J, Peloponese JM, Charloteaux B, Van den Broeke A, Hill DE, Vidal M, Dequiedt F, Twizere JC
Année : 2021
Journal : PLoS Pathog
Volume : 17
Pages : e1009919

Fluorescent Multiplex Immunohistochemistry Coupled With Other State-Of-The-Art Techniques to Systematically Characterize the Tumor Immune Microenvironment.

Auteurs : Boisson A, Noël G, Saiselet M, Rodrigues-Vitória J, Thomas N, Fontsa ML, Sofronii D, Naveaux C, Duvillier H, Craciun L, Larsimont D, Awada A, Detours V, Willard-Gallo K, Garaud S
Année : 2021
Journal : Front Mol Biosci
Volume : 8
Pages : 673042

In Vitro Cellular and Molecular Interplay between Human Foreskin-Derived Mesenchymal Stromal/Stem Cells and the Th17 Cell Pathway.

Auteurs : Najar M, Merimi M, Faour WH, Lombard CA, Moussa Agha D, Ouhaddi Y, Sokal EM, Lagneaux L, Fahmi H
Année : 2021
Journal : Pharmaceutics
Volume : 13

Endoscopic duodenal mucosal resurfacing for nonalcoholic steatohepatitis (NASH): a pilot study.

Auteurs : Hadefi A, Verset L, Pezzullo M, Rosewick N, Degré D, Gustot T, Moreno C, Devière J, Trépo E
Année : 2021
Journal : Endosc Int Open
Volume : 9
Pages : E1792-E1800